Search Results - "Vasconcellos, Marne C."

Biological activities and cytotoxicity of diterpenes from Copaifera spp. Oleoresins by de S Vargas, Fabiano, D O de Almeida, Patrícia, Aranha, Elenn Suzany P, de A Boleti, Ana Paula, Newton, Peter, de Vasconcellos, Marne C, Junior, Valdir F Veiga, Lima, Emerson S

“…Copaifera spp. are Amazonian species widely studied and whose oleoresins are used by local people for various medicinal purposes. However, a detailed study of…”
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In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon by Lima, Renata B S, Rocha e Silva, Luiz F, Melo, Marcia R S, Costa, Jaqueline S, Picanço, Neila S, Lima, Emerson S, Vasconcellos, Marne C, Boleti, Ana Paula A, Santos, Jakeline M P, Amorim, Rodrigo C N, Chaves, Francisco C M, Coutinho, Julia P, Tadei, Wanderli P, Krettli, Antoniana U, Pohlit, Adrian M

“…The anti-malarials quinine and artemisinin were isolated from traditionally used plants (Cinchona spp. and Artemisia annua, respectively). The synthetic…”
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Antiplasmodial activity of synthetic ellipticine derivatives and an isolated analog by Montoia, Andreia, Rocha e Silva, Luiz F., Torres, Zelina E., Costa, David S., Henrique, Marycleuma C., Lima, Emerson S., Vasconcellos, Marne C., Souza, Rita C.Z., Costa, Monica R.F., Grafov, Andriy, Grafova, Iryna, Eberlin, Marcos N., Tadei, Wanderli P., Amorim, Rodrigo C.N., Pohlit, Adrian M.

“…Novel and known ellipticine derivatives exhibit important in vitro inhibition of human malaria parasites. Ellipticine has been shown previously to exhibit…”
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Synthesis of 1H-1,2,3-triazoles and study of their antifungal and cytotoxicity activities by da Silva, Iara F, Martins, Prisicila R C, da Silva, Emanuelly G, Ferreira, Sabrina B, Ferreira, Vitor F, da Costa, Karen Regina C, de Vasconcellos, Marne C, Lima, Emerson S, da Silva, Fernando de C

“…We report herein the results of antifungal activity of fifteen 1,2,3-triazoles against Candida albicans, Candida krusei, Candida parapsilosis, Candida kefyr,…”
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Dentin Cleaning Ability of an Amazon Bioactive: Evaluation by Scanning Electron Microscopy by Bandeira, Maria Fulgência C L, Lima, Geisy R, Lopes, Patrícia P, Toda, Carina, Venâncio, Gisely N, Lima, Greiciane A, de Vasconcellos, Marne C, Martins, Leandro M, Sampaio, Fâbio C, Conde, Nikeila C de Oliveira

“…The role of dentin cleaning is to remove debris that may impair adaptation and marginal sealing, quantitatively reducing microorganisms. The aim of this study…”
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A new synthetic antitumor naphthoquinone induces ROS-mediated apoptosis with activation of the JNK and p38 signaling pathways by de Almeida, Patricia D.O., dos Santos Barbosa Jobim, Gleyce, dos Santos Ferreira, Caio César, Rocha Bernardes, Lucas, Dias, Rosane B., Schlaepfer Sales, Caroline B., Valverde, Ludmila de F., Rocha, Clarissa A.G., Soares, Milena B.P., Bezerra, Daniel P., de Carvalho da Silva, Fernando, Cardoso, Mariana Filomena do Carmo, Ferreira, Vitor Francisco, Brito, Larissa F., Pires de Sousa, Lirlândia, de Vasconcellos, Marne C., Lima, Emerson S.

“…Quinones are plant-derived secondary metabolites that present diverse pharmacological properties, including antibacterial, antifungal, antiviral,…”
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Synthesis and antimalarial activity of quinones and structurally-related oxirane derivatives by Carneiro, Paula F., Pinto, Maria C.R.F., Marra, Roberta K.F., da Silva, Fernando de C., Resende, Jackson A.L.C., Rocha e Silva, Luiz F., Alves, Hilkem G., Barbosa, Gleyce S., de Vasconcellos, Marne C., Lima, Emerson S., Pohlit, Adrian M., Ferreira, Vitor F.

“…A series of eighteen quinones and structurally-related oxiranes were synthesized and evaluated for in vitro inhibitory activity against the…”
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Biflorin inhibits the proliferation of gastric cancer cells by decreasing MYC expression by Barbosa-Jobim, Gleyce S., Costa-Lira, Évelyn, Ralph, Ana Carolina L., Gregório, Luciana, Lemos, Telma L.G., Burbano, Rommel R., Calcagno, Danielle Q., Smith, Marília A.C., Montenegro, Raquel C., Vasconcellos, Marne C.

“…Gastric cancer is the third leading cause of cancer-related death worldwide. To evaluate the anticancer potential and molecular mechanism of biflorin, a…”
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In vitro and in vivo anti-malarial activity of limonoids isolated from the residual seed biomass from Carapa guianensis (andiroba) oil production by Pereira, Tiago B, Rocha E Silva, Luiz F, Amorim, Rodrigo C N, Melo, Márcia R S, Zacardi de Souza, Rita C, Eberlin, Marcos N, Lima, Emerson S, Vasconcellos, Marne C, Pohlit, Adrian M

“…Carapa guianensis is a cultivable tree used by traditional health practitioners in the Amazon region to treat several diseases and particularly symptoms…”
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Bioactivity of Biflorin, a Typical o-Naphthoquinone Isolated from Capraria biflora L by Vasconcellos, Marne C., Montenegro, Raquel C., Militão, Gardênia C. G., Fonseca, Aluísio M., Pessoa, Otília D. L., Lemos, Telma L. G., Pessoa, Cláudia, Moraes, Manoel O., Costa-Lotufo, Letícia V.

“…Capraria biflora L. (Scrophulariaceae) is a perennial shrub widely distributed in several countries of tropical America. The present work verified the…”
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HPLC-DAD profile of phenolic compounds, cytotoxicity, antioxidant and anti-inflammatory activities of the amazon fruit Caryocar villosum by Yamaguchi, Klenicy Kazumi de Lima, Lamarão, Carlos Victor, Aranha, Ellen, Souza, Rodrigo Otávio Silva, Oliveira, Patrícia Danielle, Vasconcellos, Marne, Lima, Emerson Silva, Veiga-Junior, Valdir Florêncio

“…Piquiá (Caryocar villosum - Caryocaraceae) is a native fruit from the Amazon region rich in bioactive substances. Fruit pulp extracts were analyzed by HPLC,…”
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Antioxidant activity and peroxidase inhibition of Amazonian plants extracts traditionally used as anti-inflammatory by de Vargas, Fabiano S, Almeida, Patricia D O, de Boleti, Ana Paula A, Pereira, Maria M, de Souza, Tatiane P, de Vasconcellos, Marne C, Nunez, Cecilia Veronica, Pohlit, Adrian M, Lima, Emerson S

“…The Amazon is the largest rainforest in the world and is home to a rich biodiversity of medicinal plants. Several of these plants are used by the local…”
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The in-vitro and in-vivo inhibitory activity of biflorin in melanoma by Vasconcellos, Marne C, Bezerra, Daniel P, Fonseca, Aluísio M, Araújo, Ana Jérsia, Pessoa, Cláudia, Lemos, Telma L G, Costa-Lotufo, Letícia V, de Moraes, Manoel Odorico, Montenegro, Raquel C

“…Biflorin, an ortho-naphthoquinone, is an active compound found in the roots of Capraria biflora L. It has been reported that biflorin presents anticancer…”
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Evaluation of the cytotoxic and antimutagenic effects of biflorin, an antitumor 1,4 o-naphthoquinone isolated from Capraria biflora L by Vasconcellos, Marne C, Moura, Dinara J, Rosa, Renato M, Machado, Miriana S, Guecheva, Temenouga N, Villela, Izabel, Immich, Bruna F, Montenegro, Raquel C, Fonseca, Aluísio M, Lemos, Telma L. G, Moraes, Maria Elisabete A, Saffi, Jenifer, Costa-Lotufo, Letícia V, Moraes, Manoel O, Henriques, João A. P

“…Biflorin is a natural quinone isolated from Capraria biflora L. Previous studies demonstrated that biflorin inhibits in vitro and in vivo tumor cell growth and…”
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Synthesis and biological evaluation of cytotoxic properties of stilbene-based resveratrol analogs by de Lima, Dênis Pires, Rotta, Rodrigo, Beatriz, Adilson, Marques, Maria Rita, Montenegro, Raquel C., Vasconcellos, Marne C., Pessoa, Cláudia, de Moraes, Manoel O., Costa-Lotufo, Letícia V., Frankland Sawaya, Alexandra Christine Helena, Eberlin, Marcos Nogueira

“…This work deals with the preparation of stilbene-based resveratrol analogs by employing the Perkin reaction, aiming at synthesizing potential antitumor lead…”
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Piplartine induces genotoxicity in eukaryotic but not in prokaryotic model systems by Bezerra, Daniel P., Vasconcellos, Marne C., Machado, Miriana S., Villela, Izabel V., Rosa, Renato M., Moura, Dinara J., Pessoa, Cláudia, Moraes, Manoel O., Silveira, Edilberto R., Lima, Mary Anne S., Aquino, Nayara C., Henriques, João Antonio P., Saffi, Jenifer, Costa-Lotufo, Letícia V.

“…Piplartine {5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone} is an alkamide present in Piper species that exhibits…”
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Genotoxicity of 15-deoxygoyazensolide in bacteria and yeast by Vasconcellos, Marne C., Rosa, Renato M., Machado, Miriana S., Villela, Izabel V., Crotti, Antônio Eduardo Miller, Lopes, João Luis Callegari, Pessoa, Cláudia, de Moraes, Manoel Odorico, Lopes, Norberto Peporine, Costa-Lotufo, Letícia V., Saffi, Jenifer, Henriques, João Antônio Pegas

“…Sesquiterpene lactones (SLs) present a wide range of pharmacological activities. The aim of our study was to investigate the genotoxicity of…”
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Erratum to: Antioxidant activity and peroxidase inhibition of Amazonian plants extracts traditionally used as anti-inflammatory by Vargas, Fabiano de S, Almeida, Patricia D O, de Boleti, Ana Paula A, Pereira, Maria M, de Souza, Tatiane P, de Vasconcellos, Marne C, Nunez, Cecilia Veronica, Pohlit, Adrian M, Lima, Emerson S

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CYP450 Metabolism of a Semisynthetic Naphthoquinone, an Anticancer Drug Candidate, by Human Liver Microsomes by Costa, Edna, Carrão, Daniel, Bucci, Jade, Oliveira, Anderson, Machado, Tallita, Ferreira, Vitor, Lima, Émerson, Vasconcellos, Marne, Magalhães, Igor

“…CNFD (6b,7-dihydro-5H-cyclopenta[b]naphtho[2,1-d]furan-5,6(9aH)-dione) is a semisynthetic naphthoquinone derived from lawsone that has cytotoxic action in…”
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Synthesis, molecular docking, and biological activity of thioether derived from juglone in preclinical models of chronic myeloid leukemia by de S. Portilho, Adrhyann J., B. S. M. R. Gomes, Carinne, Moreira, Caroline S., da S. M. Forezi, Luana, Cordeiro, Pâmella S., do Nascimento, Vanessa, Daniel, Julio P., Vasconcellos, Marne C., E. A. de Moraes, Maria, de F. A. Moreira-Nunes, Caroline, Ferreira, Vitor F., Montenegro, Raquel C., da Rocha, David R.

“…[Display omitted] In this work, 16 new thio-1,4-naphthoquinones were synthesized, and their antiproliferative effects against tumor cell lines SK-MEL-19,…”
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