Search Results - "Vasavi, C.S."

Exploring the drug resistance mechanism of active site, non-active site mutations and their cooperative effects in CRF01_AE HIV-1 protease: molecular dynamics simulations and free energy calculations by C.S., Vasavi, Tamizhselvi, Ramasamy, Munusami, Punnagai

“…Human immunodeficiency virus type 1 protease is essential for virus replication and maturation and has been considered as one of the important drug target for…”
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Evaluation of DNA/Protein interactions and cytotoxic studies of copper(II) complexes incorporated with N, N donor ligands and terpyridine ligand by Tummalapalli, Kiran, C.S, Vasavi, Munusami, Punnagai, Pathak, Madhvesh, M.M., Balamurali

“…[Display omitted] A series of four new heteroleptic derivatives of copper(II) synthesized and structurally characterized as a distorted square-pyramidal…”
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Design, synthesis and identification of novel coumaperine derivatives for inhibition of human 5-LOX: Antioxidant, pseudoperoxidase and docking studies by Muthuraman, Subramani, Sinha, Shweta, Vasavi, C.S., Waidha, Kamran Manzoor, Basu, Biswarup, Munussami, Punnagai, Balamurali, M.M., Doble, Mukesh, Saravana Kumar, Rajendran

“…Pepper based compounds developed as potent 5-LOX inhibitors. Coumaperine derivatives substituted with multiple methoxy and hydroxyl groups exhibited high 5-LOX…”
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Synthesis, spectroscopic characterization and in vitro studies of new heteroleptic copper (II) complexes derived from 2-hydroxy napthaldehyde Schiff’s bases and N, N donor ligands: Antimicrobial, DNA binding and cytotoxic investigations by Kiran, Tummalapalli, Prasanth, Vuppalapati Giri, Balamurali, M.M., Vasavi, C.S., Munusami, Punnagai, Sathiyanarayanan, Kulathu Iyer, Pathak, Madhvesh

“…Eight novel metallacyclic derivatives of copper (II) have been synthesized and structurally characterized as a pent-coordination around central metal…”
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2,3-Dihydroquinazolin-4(1H)-ones: Visible light mediated synthesis, solvatochromism and biological activity by Hemalatha, K., Madhumitha, G., Vasavi, C.S., Munusami, Punnagai

“…[Display omitted] •2,3-Dihydroquinazolin-4(1H)-ones synthesized under visible light.•Solvatochromism studies have been carried out.•In vitro anti-inflammatory…”
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Drug Resistance Mechanism of L10F, L10F/N88S and L90M mutations in CRF01_AE HIV-1 protease: Molecular dynamics simulations and binding free energy calculations by Vasavi, C.S., Tamizhselvi, Ramasamy, Munusami, Punnagai

“…[Display omitted] •The molecular basis of NFV resistance due to strongly linked L10F/N88S mutation and L90M mutation in AE-protease was analyzed.•Due to…”
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In Silico Molecular Docking and In Vitro Antidiabetic Studies of Dihydropyrimido[4,5-a]acridin-2-amines by Roopan, Selvaraj Mohana, Bharathi, A., Vasavi, C. S., Munusami, Punnagai, Gayathri, G. A., Gayathri, M.

“…An in vitro antidiabetic activity on α-amylase and α–glucosidase activity of novel…”
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Computational Modeling and Simulation of Biomolecular Motors by Shwetha, M., Suchitra, M., Vasavi, C.S., Radhagayathri, K.U., Krishnan, N.P.K., Gopakumar, D.

“…Molecular motors can be considered as biological molecular devices that are indispensable agents or machines for movement in living organisms. The most common…”
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