Search Results - "Vasandani, Vivek"

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    Post‐translational modification sites are present in hydrophilic cavities of alpha‐synuclein, tau, FUS, and TDP‐43 fibrils: A molecular dynamics study by Kochen, Noah Nathan, Seaney, Darren, Vasandani, Vivek, Murray, Marguerite, Braun, Anthony R., Sachs, Jonathan N.

    “…Hydration plays a crucial role in the refolding of intrinsically disordered proteins into amyloid fibrils; however, the specific interactions between water and…”
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  2. 2

    Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth by Nathan Kochen, Noah, Vasandani, Vivek, Seaney, Darren, Pandey, Anil K., Walters, Michael A., Braun, Anthony R., Sachs, Jonathan N.

    Published in ACS chemical neuroscience (07-09-2022)
    “…Recent high-resolution structures of alpha-synuclein (aSyn) fibrils offer promise for rational approaches to drug discovery for Parkinson’s disease and Lewy…”
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    Journal Article