Search Results - "Vasandani, Vivek"
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Post‐translational modification sites are present in hydrophilic cavities of alpha‐synuclein, tau, FUS, and TDP‐43 fibrils: A molecular dynamics study
Published in Proteins, structure, function, and bioinformatics (01-07-2024)“…Hydration plays a crucial role in the refolding of intrinsically disordered proteins into amyloid fibrils; however, the specific interactions between water and…”
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Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth
Published in ACS chemical neuroscience (07-09-2022)“…Recent high-resolution structures of alpha-synuclein (aSyn) fibrils offer promise for rational approaches to drug discovery for Parkinson’s disease and Lewy…”
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Journal Article