Search Results - "Vasan, Richa"

Unravelling transcriptomic complexity in breast cancer through modulation of DARPP-32 expression and signalling pathways by Saidy, Behnaz, Vasan, Richa, Durant, Rosie, Greener, Megan-Rose, Immanuel, Adelynn, Green, Andrew R., Rakha, Emad, Ellis, Ian, Ball, Graham, Martin, Stewart G., Storr, Sarah J.

“…DARPP-32 is a key regulator of protein-phosphatase-1 (PP-1) and protein kinase A (PKA), with its function dependent upon its phosphorylation state. We…”
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In silico profiling and structural insights of missense mutations in RET protein kinase domain by molecular dynamics and docking approach by George Priya Doss, C, Rajith, B, Chakraboty, Chiranjib, Balaji, V, Magesh, R, Gowthami, B, Menon, Sneha, Swati, M, Trivedi, Manjari, Paul, Jasmine, Vasan, Richa, Das, Maitreya

“…A major challenge remaining in drug design efforts towards protein kinase is due to the development of drug resistance initiated by the missense mutations in…”
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Shelterin Proteins and Cancer by Patel, Trupti NV, Vasan, Richa, Gupta, Divanshu, Patel, Jay, Trivedi, Manjari

“…The telomeric end structures of the DNA are known to contain tandem repeats of TTAGGG sequence bound with specialised protein complex called the "shelterin…”
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MBTPS2 acts as a regulator of lipogenesis and cholesterol synthesis through SREBP signalling in prostate cancer by Tibbo, Amy J., Hartley, Andrew, Vasan, Richa, Shaw, Robin, Galbraith, Laura, Mui, Ernest, Leung, Hing Y., Ahmad, Imran

“…Background Prostate cancer is the most common cancer in men in the developed world, with most deaths caused by advanced and metastatic disease which has no…”
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High BMP7 expression is associated with poor prognosis in ovarian cancer by Vasan, Richa, Yadav, Jahnavi, Aiyappa‐Maudsley, Radhika, Deen, Suha, Storr, Sarah J., Martin, Stewart G.

“…Abstract Bone Morphogenetic Protein 7 (BMP7) is an extracellular signalling protein that belongs to the transforming growth factor‐β (TGF‐ β) superfamily…”
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An evaluation in vitro of the efficacy of nutlin-3 and topotecan in combination with 177Lu-DOTATATE for the treatment of neuroblastoma by Tesson, Mathias, Vasan, Richa, Hock, Andreas, Nixon, Colin, Rae, Colin, Gaze, Mark, Mairs, Robert

“…Targeted radiotherapy of metastatic neuroblastoma using the somatostatin receptor (SSTR)-targeted octreotide analogue DOTATATE radiolabelled with lutetium-177…”
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A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma by Birch, Joanna L, Strathdee, Karen, Gilmour, Lesley, Vallatos, Antoine, McDonald, Laura, Kouzeli, Ariadni, Vasan, Richa, Qaisi, Abdulrahman Hussain, Croft, Daniel R, Crighton, Diane, Gill, Kathryn, Gray, Christopher H, Konczal, Jennifer, Mezna, Mokdad, McArthur, Duncan, Schüttelkopf, Alexander W, McConnell, Patricia, Sime, Mairi, Holmes, William M, Bower, Justin, McKinnon, Heather J, Drysdale, Martin, Olson, Michael F, Chalmers, Anthony J

“…Glioblastoma (GBM) is an aggressive and incurable primary brain tumor that causes severe neurologic, cognitive, and psychologic symptoms. Symptoms are caused…”
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Abstract LB009: Unveiling the significance of DARPP-32 and its partners, including GRB7 and DKK1, in breast cancer: Integrative insights from patient data and cell line transcriptomics by Saidy, Behnaz, Vasan, Richa, Greener, Megan-Rose, Durrant, Rosie, Immanuel, Adelynn, Green, Andrew, Rakha, Emad, Ellis, Ian, Ball, Graham, Martin, Stewart, Storr, Sarah J.

“…Abstract DARPP-32 plays a crucial role in regulating both protein-phosphatase-1 (PP-1) and protein kinase A (PKA), its function being reliant on its…”
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Shelterin Proteins and Cancer by Patel, Trupti NV, Vasan, Richa, Gupta, Divanshu, Patel, Jay, Trivedi, Manjari

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An evaluation in vitro of the efficacy of nutlin-3 and topotecan in combination with 177 Lu-DOTATATE for the treatment of neuroblastoma by Tesson, Mathias, Vasan, Richa, Hock, Andreas, Nixon, Colin, Rae, Colin, Gaze, Mark, Mairs, Robert

“…Targeted radiotherapy of metastatic neuroblastoma using the somatostatin receptor (SSTR)-targeted octreotide analogue DOTATATE radiolabelled with lutetium-177…”
Get full text

Shelterin proteins and cancer by Patel, Trupti Nv, Vasan, Richa, Gupta, Divanshu, Patel, Jay, Trivedi, Manjari

“…The telomeric end structures of the DNA are known to contain tandem repeats of TTAGGG sequence bound with specialised protein complex called the "shelterin…”
Get more information