Search Results - "Vas, Jaya"
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Immunology of Mercury
Published in Annals of the New York Academy of Sciences (01-11-2008)“…The heavy metal mercury is ubiquitously distributed in the environment resulting in permanent low‐level exposure in human populations. Mercury can be…”
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Natural antibody to apoptotic cell membranes inhibits the proinflammatory properties of lupus autoantibody immune complexes
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-10-2012)“…Objective Naturally arising IgM antibodies (NAb) to apoptotic cell (AC) determinants are present from birth and can be further induced by AC challenge. In…”
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Protective autoantibodies in the rheumatic diseases: lessons for therapy
Published in Nature reviews. Rheumatology (01-05-2013)“…Pathogenic IgG autoantibodies have established roles in diseases including systemic lupus erythematosus and rheumatoid arthritis. Less familiar are the…”
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Lymphocyte Activation Gene-3 (LAG-3) negatively regulates environmentally-induced autoimmunity
Published in PloS one (14-08-2014)“…Environmental factors including drugs, mineral oils and heavy metals such as lead, gold and mercury are triggers of autoimmune diseases in animal models or…”
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MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses
Published in Proceedings of the National Academy of Sciences - PNAS (27-11-2012)“…Naturally arising IgM antibodies, which recognize neo-determinants on apoptotic cell (AC) membranes, are present from birth and can be further induced by AC…”
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Protective Roles of Natural IgM Antibodies
Published in Frontiers in immunology (01-01-2012)“…Antibodies are a vital part of the armamentarium of the adaptive immune system for the fine-tuning of the recognition and response to foreign threats. However,…”
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Regulation of Dendritic Cells and Macrophages by an Anti-Apoptotic Cell Natural Antibody that Suppresses TLR Responses and Inhibits Inflammatory Arthritis
Published in The Journal of immunology (1950) (15-07-2009)“…Although natural Abs (NAbs) are present from birth, little is known about what drives their selection and whether they have housekeeping functions. The…”
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Fundamental roles of the innate-like repertoire of natural antibodies in immune homeostasis
Published in Frontiers in immunology (2013)“…The composition of the early immune repertoire is biased with prominent expression of spontaneously arising B cell clones that produce IgM with recurrent and…”
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9
Lymphocyte Activation Gene-3
Published in PloS one (14-08-2014)“…Environmental factors including drugs, mineral oils and heavy metals such as lead, gold and mercury are triggers of autoimmune diseases in animal models or…”
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Safety and efficacy of sunitinib in patients from Latin America: subanalysis of an expanded access trial in metastatic renal cell carcinoma
Published in OncoTargets and therapy (01-01-2016)“…Sunitinib is an approved treatment for metastatic renal cell carcinoma (mRCC). The safety profile and efficacy of sunitinib were confirmed in a global expanded…”
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Regulatory Roles for NKT Cell Ligands in Environmentally Induced Autoimmunity
Published in The Journal of immunology (1950) (15-11-2008)“…The development of autoimmune diseases is frequently linked to exposure to environmental factors such as chemicals, drugs, or infections. In the experimental…”
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Regulatory Roles for NKT Cell Ligands in Environmentally Induced Autoimmunity1
Published in The Journal of immunology (1950) (15-11-2008)“…The development of autoimmune diseases is frequently linked to exposure to environmental factors such as chemicals, drugs, or infections. In the experimental…”
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Natural autoantibodies to apoptotic cell membranes regulate fundamental innate immune functions and suppress inflammation
Published in Discovery medicine (01-10-2009)“…The evolution of the immune system has provided a multilevel system that interconnects the innate and adaptive immune systems to serve at least three central…”
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Lymphocyte Activation Gene-3 (LAG-3) Negatively Regulates Environmentally-Induced Autoimmunity: e104484
Published in PloS one (01-08-2014)“…Environmental factors including drugs, mineral oils and heavy metals such as lead, gold and mercury are triggers of autoimmune diseases in animal models or…”
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Activation of NKT cells exacerbates environmentally induced autoimmunity (130.23)
Published in The Journal of immunology (1950) (01-04-2007)“…Administration of subtoxic doses of mercuric chloride to genetically susceptible mice induces an autoimmune syndrome with anti-nucleolar antibody production,…”
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Regulatory roles for natural killer T cells and Toll -like receptors in mercury-induced autoimmunity
Published 01-01-2008“…The development of autoimmune diseases is frequently linked to exposure to environmental factors such as chemicals, drugs or infections. In the experimental…”
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