Search Results - "Varzari, Alexander"

Synergistic effect of genetic polymorphisms in TLR6 and TLR10 genes on the risk of pulmonary tuberculosis in a Moldavian population by Varzari, Alexander, Deyneko, Igor V., Tudor, Elena, Grallert, Harald, Illig, Thomas

“…Polymorphisms in genes that control immune function and regulation may influence susceptibility to pulmonary tuberculosis (TB). In this study, 14 polymorphisms…”
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Modeling and cleaning RNA-seq data significantly improve detection of differentially expressed genes by Deyneko, Igor V, Mustafaev, Orkhan N, Tyurin, Alexander Ð, Zhukova, Ksenya V, Varzari, Alexander, Goldenkova-Pavlova, Irina V

“…Abstract Background RNA-seq has become a standard technology to quantify mRNA. The measured values usually vary by several orders of magnitude, and while the…”
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Candidate genes and sequence variants for susceptibility to mycobacterial infection identified by whole-exome sequencing by Varzari, Alexander, Deyneko, Igor V., Bruun, Gitte Hoffmann, Dembic, Maja, Hofmann, Winfried, Cebotari, Victor M., Ginda, Sergei S., Andresen, Brage S., Illig, Thomas

“…Inborn errors of immunity are known to influence susceptibility to mycobacterial infections. The aim of this study was to characterize the genetic profile of…”
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Analysis of polymorphisms in RIG-I-like receptor genes in German multiple sclerosis patients by Varzari, Alexander, Bruch, Kathrin, Deyneko, Igor V, Chan, Andrew, Epplen, Joerg T, Hoffjan, Sabine

“…Abstract Variation in genes encoding retinoid acid-inducible gene I (RIG-I)-like receptors (RLRs) has been implicated in the pathogenesis of autoimmune…”
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Paleo-Balkan and Slavic contributions to the genetic pool of Moldavians: insights from the Y chromosome by Varzari, Alexander, Kharkov, Vladimir, Nikitin, Alexey G, Raicu, Florina, Simonova, Kseniya, Stephan, Wolfgang, Weiss, Elisabeth H, Stepanov, Vadim

“…Moldova has a rich historical and cultural heritage, which may be reflected in the current genetic makeup of its population. To date, no comprehensive studies…”
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Population history of the Dniester-Carpathians: evidence from Alu markers by Varzari, Alexander, Stephan, Wolfgang, Stepanov, Vadim, Raicu, Florina, Cojocaru, Radu, Roschin, Yuri, Glavce, Cristiana, Dergachev, Valentin, Spiridonova, Maria, Schmidt, Horst D, Weiss, Elisabeth

“…The area between the Dniester and the eastern Carpathian mountain range is at a geographical crossroads between eastern Europe and the Balkans. Little is known…”
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Association between STAT4 gene polymorphism and susceptibility to pulmonary tuberculosis in the Moldavian population by Varzari, Alexander, Tudor, Elena, Corloteanu, Andrei, Axentii, Ecaterina, Vladei, Iurie, Deyneko, Igor V.

“…Signal transducer and activator of transcription 4 (STAT4) plays a crucial role in the host immune response against Mycobacterium tuberculosis. This study…”
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Genetic variation in TLR pathway and the risk of pulmonary tuberculosis in a Moldavian population by Varzari, Alexander, Deyneko, Igor V., Vladei, Iuri, Grallert, Harald, Schieck, Maximilian, Tudor, Elena, Illig, Thomas

“…Toll-like receptors (TLRs) play a critical role in initiating an immune response to infections. In this study, we examined whether single nucleotide…”
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Synergistic effect of genetic polymorphisms in and genes on the risk of pulmonary tuberculosis in a Moldavian population by Alexander Varzari, Igor V. Deyneko, Elena Tudor, Harald Grallert, Thomas Illig

“…Polymorphisms in genes that control immune function and regulation may influence susceptibility to pulmonary tuberculosis (TB). In this study, 14 polymorphisms…”
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Staged Combined Endovascular and Open Surgical Approach in a Patient with Takayasu's Arteritis by Varzari, Alexander, Rathore, Animesh, Shah, Rasesh M., Panneton, Jean M.

“…Takayasu's arteritis (TA) is a systemic large vessel vasculitis that affects the aorta and its branches. Most patients with TA respond to medical therapy with…”
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Age-Specific Association of CCL5 Gene Polymorphism with Pulmonary Tuberculosis: A Case-Control Study by Varzari, Alexander, Tudor, Elena, Bodrug, Nina, Corloteanu, Andrei, Axentii, Ecaterina, Deyneko, Igor V

“…Chemokines play a key role in immune regulation and response, and have been implicated in the pathogenesis of tuberculosis (TB). In this study, we investigated…”
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Searching for the origin of Gagauzes: Inferences from Y-chromosome analysis by Varzari, Alexander, Kharkov, Vladimir, Stephan, Wolfgang, Dergachev, Valentin, Puzyrev, Valery, Weiss, Elisabeth H., Stepanov, Vadim

“…The Gagauzes are a small Turkish‐speaking ethnic group living mostly in southern Moldova and northeastern Bulgaria. The origin of the Gagauzes is obscure. They…”
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Polymorphisms of glutathione S-transferase and methylenetetrahydrofolate reductase genes in Moldavian patients with ulcerative colitis: Genotype-phenotype correlation by Varzari, Alexander, Deyneko, Igor V., Tudor, Elena, Turcan, Svetlana

“…Glutathione S-transferases (GSTM1, GSTT1, and GSTP1) and methylenetetrahydrofolate reductase (MTHFR) are important enzymes for protection against oxidative…”
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Staged Combined Endovascular and Open Surgical Approach in a Patient with Takayasu's Arteritis by Varzari, Alexander, Rathore, Animesh, Shah, Rasesh M, Panneton, Jean M

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