Search Results - "Varvarigou, Alexandra D"

Synthesis and comparative assessment of a labeled RGD peptide bearing two different 99mTc-tricarbonyl chelators for potential use as targeted radiopharmaceutical by Psimadas, Dimitrios, Fani, Melpomeni, Gourni, Eleni, Loudos, George, Xanthopoulos, Stavros, Zikos, Christos, Bouziotis, Penelope, Varvarigou, Alexandra D.

“…During the past decade radiolabeled RGD-peptides have been extensively studied to develop site-directed targeting vectors for integrins. Integrins are…”
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(99m)Tc-labeled aminosilane-coated iron oxide nanoparticles for molecular imaging of ανβ3-mediated tumor expression and feasibility for hyperthermia treatment by Tsiapa, Irene, Efthimiadou, Eleni K, Fragogeorgi, Eirini, Loudos, George, Varvarigou, Alexandra D, Bouziotis, Penelope, Kordas, George C, Mihailidis, Dimitris, Nikiforidis, George C, Xanthopoulos, Stavros, Psimadas, Dimitrios, Paravatou-Petsotas, Maria, Palamaris, Lazaros, Hazle, John D, Kagadis, George C

“…Dual-modality imaging agents, such as radiolabeled iron oxide nanoparticles (IO-NPs), are promising candidates for cancer diagnosis and therapy. We developed…”
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Co-administration of succinylated gelatine with a (99m)Tc-bombesin analogue, effects on pharmacokinetics and tumor uptake by Liolios, Christos C, Xanthopoulos, Stavros, Loudos, George, Varvarigou, Alexandra D, Sivolapenko, Gregory B

“…The bombesin analogue, [(99m)Tc-GGC]-(Ornithine)3-BN(2-14), (99m)Tc-BN-O, targeting gastrin releasing peptide receptors (GRPrs) on the surface of tumors, was…”
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Polymeric micelles and vesicles: biological behavior evaluation using radiolabeling techniques by Psimadas, Dimitrios, Oliveira, Hugo, Thevenot, Julie, Lecommandoux, Sebastien, Bouziotis, Penelope, Varvarigou, Alexandra D., Georgoulias, Panagiotis, Loudos, George

“…Abstract The application of combined diagnosis and therapy through nanotechnology applications is attracting increasing attention worldwide. Polymeric…”
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Radiochemical and radiobiological assessment of a pyridyl-S-cysteine functionalized bombesin derivative labeled with the (99m)Tc(CO)3(+) core by Bouziotis, Penelope, Gourni, Eleni, Patsis, George, Psimadas, Dimitrios, Zikos, Christos, Fani, Melpomeni, Xanthopoulos, Stavros, Loudos, George, Paravatou-Petsotas, Maria, Livaniou, Evangelia, Varvarigou, Alexandra D, Pirmettis, Ioannis, Papadopoulos, Minas

“…Bombesin is a neuropeptide widely studied due to its ability to target various types of cancers. Technetium-99m on the other hand is ideal for diagnostic tumor…”
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Radiochemical and radiobiological assessment of a pyridyl-S-cysteine functionalized bombesin derivative labeled with the 99mTc(CO)3+ core by Bouziotis, Penelope, Gourni, Eleni, Patsis, George, Psimadas, Dimitrios, Zikos, Christos, Fani, Melpomeni, Xanthopoulos, Stavros, Loudos, George, Paravatou-Petsotas, Maria, Livaniou, Evangelia, Varvarigou, Alexandra D., Pirmettis, Ioannis, Papadopoulos, Minas

“…Bombesin is a neuropeptide widely studied due to its ability to target various types of cancers. Technetium-99m on the other hand is ideal for diagnostic tumor…”
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Structural Assessment and Biological Evaluation of Two N3S Bombesin Derivatives by Gourni, Eleni, Bouziotis, Penelope, Benaki, Dimitra, Loudos, George, Xanthopoulos, Stavros, Paravatou-Petsotas, Maria, Mavri-Vavagianni, Maria, Pelecanou, Maria, Archimandritis, Spyros C, Varvarigou, Alexandra D

“…The aim of the present study is the evaluation of the 99mTc complexes of two bombesin-like peptides: Gly1′-Gly2′-Cys3′-Aca-BN[2−14] (BN-1.1) and…”
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Structural modifications of 99mTc-labelled bombesin-like peptides for optimizing pharmacokinetics in prostate tumor targeting by Liolios, Christos C., Fragogeorgi, Eirini A., Zikos, Christos, Loudos, George, Xanthopoulos, Stavros, Bouziotis, Penelope, Paravatou-Petsotas, Maria, Livaniou, Evangelia, Varvarigou, Alexandra D., Sivolapenko, Gregory B.

“…The main goal of the present study was to investigate the importance of the addition of a positively charged aa in the naturally occurring Bombesin (BN)…”
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Evaluation of ανβ3-mediated tumor expression with a 99mTc-labeled ornithine-modified RGD derivative during glioblastoma growth in vivo by Tsiapa, Irene, Loudos, George, Fragogeorgi, Eirini A, Bouziotis, Penelope, Psimadas, Dimitrios, Xanthopoulos, Stavros, Paravatou-Petsotas, Maria, Palamaris, Lazaros, Varvarigou, Alexandra D, Karnabatidis, Dimitris, Kagadis, George C

“…In this study, a novel way of distinguishing the intrinsic relationship between ανβ3 integrin targeting and detection of tumor growth by using a radiolabeled…”
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Use of radiolabeled bombesin in humans by Scopinaro, Francesco, De Vincentis, Giuseppe, Varvarigou, Alexandra D

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Structural Study by NMR of an Oxorhenium−RGD Decapeptide Complex for Application in Radiotherapy by Costopoulos, Basil, Benaki, Dimitra, Pelecanou, Maria, Mikros, Emmanuel, Stassinopoulou, Chariklia I, Varvarigou, Alexandra D, Archimandritis, Spyridon C

“…The decapeptide Arg-Gly-Asp-Ser-Cys-Arg-Gly-Asp-Ser-Tyr, which contains two Arg-Gly-Asp (RGD) moieties in its sequence, has been successfully labeled with…”
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Comparative Evaluation of Linear and Cyclic 99mTc-RGD Peptides for Targeting of Integrins in Tumor Angiogenesis by FANI, Melpomeni, PSIMADAS, Dimitrios, ZIKOS, Christos, XANTHOPOULOS, Stavros, LOUDOS, George K, BOUZIOTIS, Penelope, VARVARIGOU, Alexandra D

“…Cell adhesion molecules, such as integrins, play a vital role in angiogenesis, a key pathway for tumor growth, invasion and metastasis. The integrin α v β 3…”
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Evaluation of a Series of New 99mTc-labeled Bombesin-like Peptides for Early Cancer Detection by GOURNI, Eleni, PARAVATOU, Maria, BOUZIOTIS, Penelope, ZIKOS, Christos, FANI, Melpomeni, XANTHOPOULOS, Stavros, ARCHIMANDRITIS, Spyridon C, LIVANIOU, Evagelia, VARVARIGOU, Alexandra D

“…Bombesin (BN) is a peptide exhibiting a high affinity for the gastrin-releasing peptide (GRP) receptor, which is overexpressed by a variety of tumors,…”
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99mTc-bombesin detects prostate cancer and invasion of pelvic lymph nodes by SCOPINARO, Francesco, DE VINCENTIS, Giuseppe, VARVARIGOU, Alexandra D, LAURENTI, Cesare, IORI, Francesco, REMEDIANI, Silvia, CHIARINI, Stella, STELLA, Salvatore

“…Biopsy is the standard method for the diagnosis of prostate cancer; however, it is inadequate for the assessment of lymph node invasion. Radionuclide imaging…”
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Tridentate ligands containing the SNS donor atom set as a novel backbone for the development of technetium brain-imaging agents by Mastrostamatis, Spiros G, Papadopoulos, Minas S, Pirmettis, Ioannis C, Paschali, Evagelia, Varvarigou, Alexandra D, Stassinopoulou, Chariklia I, Raptopoulou, Cathrine P, Terzis, Aris, Chiotellis, Efstratios

“…In developing 99mTc complexes as potential brain-imaging agents, we investigated the coordination chemistry of ligands containing sulfur and nitrogen donor…”
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Co-administration of succinylated gelatine with a 99m Tc-bombesin analogue, effects on pharmacokinetics and tumor uptake by Liolios, Christos C., Xanthopoulos, Stavros, Loudos, George, Varvarigou, Alexandra D., Sivolapenko, Gregory B.

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Co-administration of succinylated gelatine with a 99mTc-bombesin analogue, effects on pharmacokinetics and tumor uptake by Liolios, Christos C., Xanthopoulos, Stavros, Loudos, George, Varvarigou, Alexandra D., Sivolapenko, Gregory B.

“…The bombesin analogue, [99mTc-GGC]-(Ornithine)3-BN(2-14), 99mTc-BN-O, targeting gastrin releasing peptide receptors (GRPrs) on the surface of tumors, was…”
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Co-administration of succinylated gelatine with a99m Tc-bombesin analogue, effects on pharmacokinetics and tumor uptake by Liolios, Christos C, Xanthopoulos, Stavros, Loudos, George, Varvarigou, Alexandra D, Sivolapenko, Gregory B

“…Abstract The bombesin analogue, [99m Tc-GGC]-(Ornithine)3 -BN(2-14), 99m Tc-BN-O , targeting gastrin releasing peptide receptors (GRPrs) on the surface of…”
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Spacer Site Modifications for the Improvement of the in Vitro and in Vivo Binding Properties of 99mTc-N3S-X-Bombesin[2−14] Derivatives by Fragogeorgi, Eirini A, Zikos, Christos, Gourni, Eleni, Bouziotis, Penelope, Paravatou-Petsotas, Maria, Loudos, George, Mitsokapas, Nikolaos, Xanthopoulos, Stavros, Mavri-Vavayanni, Mary, Livaniou, Evangelia, Varvarigou, Alexandra D, Archimandritis, Spyridon C

“…It has been shown that gastrin releasing peptide receptors (GRPRs) are overexpressed in various types of cancer cells. Bombesin is an analogue of the mammalian…”
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99mTc-labeled aminosilane-coated iron oxide nanoparticles for molecular imaging of ανβ3-mediated tumor expression and feasibility for hyperthermia treatment by Tsiapa, Irene, Efthimiadou, Eleni K., Fragogeorgi, Eirini, Loudos, George, Varvarigou, Alexandra D., Bouziotis, Penelope, Kordas, George C., Mihailidis, Dimitris, Nikiforidis, George C., Xanthopoulos, Stavros, Psimadas, Dimitrios, Paravatou-Petsotas, Maria, Palamaris, Lazaros, Hazle, John D., Kagadis, George C.

“…[Display omitted] •Synthesis and characterization of RGD modified IO-NPs.•In vitro % cell viability evaluation by MTT assay.•In vivo biodistribution study…”
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