Search Results - "Vartika Tomar"
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A review on electrochemical detection of serotonin based on surface modified electrodes
Published in Biosensors & bioelectronics (01-06-2018)“…Serotonin is one of the important neurotransmitters of our body. It’s abnormal concentration is associated with multiple disorders and diseases. Sensitive and…”
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Base-Free Suzuki–Miyaura Coupling Reaction Using Palladium(II) Supported Catalyst in Water
Published in Catalysis letters (01-06-2019)“…The carbon–carbon bond formation via Suzuki–Miyaura reaction was performed in water as green solvent. Pd(OAc) 2 (PPh 3 ) 2 supported on magnesium hydroxide and…”
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Noscapine and its Analogs as Chemotherapeutic Agent: Current updates
Published in Current topics in medicinal chemistry (01-01-2017)“…Recently, noscapine was reported as anticancer drug. Unlike, colchicine and podophyllotoxin, noscapine did not depolymerize microtubules even at stoichiometric…”
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Cinnamon attenuates adiposity and affects the expression of metabolic genes in Diet-Induced obesity model of zebrafish
Published in Artificial cells, nanomedicine, and biotechnology (01-12-2019)“…The prevalence of obesity is increasing at an alarming rate worldwide with about 30% of the world population classified as obese. Obese body structure results…”
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Privileged Scaffold Chalcone: Synthesis, Characterization and Its Mechanistic Interaction Studies with BSA Employing Spectroscopic and Chemoinformatics Approaches
Published in ACS omega (11-02-2020)“…Chalcone, a privileged structure, is considered as an effective template in the field of medicinal chemistry for potent drug discovery. In the present study, a…”
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Deciphering the Binding Mechanism of Noscapine with Lysozyme: Biophysical and Chemoinformatic Approaches
Published in ACS omega (01-10-2019)“…Lysozyme is a well-characterized protein in terms of its structure, dynamics, and functions. It has thus emerged as a potential target to understand…”
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Implications of nanoscale based drug delivery systems in delivery and targeting tubulin binding agent, noscapine in cancer cells
Published in Current drug metabolism (01-12-2012)“…Noscapine, a tubulin binding anticancer agent undergoing Phase I/II clinical trials, inhibits tumor growth in nude mice bearing human xenografts of breast,…”
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Antibacterial and Pharmacological Evaluation of Fluoroquinolones: A Chemoinformatics Approach
Published in Genomics & informatics (01-09-2018)“…Fluoroquinolone (FQ) antibiotics are an important class of synthetic antibacterial agents. These are the most extensively used drugs for treating bacterial…”
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Hepatobiliary manganese homeostasis is dynamic in the setting of inflammation or infection in mice
Published in The FASEB journal (01-09-2023)“…Manganese is a diet‐derived micronutrient that is essential for critical cellular processes like redox homeostasis, protein glycosylation, and lipid and…”
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A new biocompatible ternary Layered Double Hydroxide Adsorbent for ultrafast removal of anionic organic dyes
Published in Scientific reports (07-11-2019)“…It would be of great significance to introduce a new biocompatible Layered Double Hydroxide (LDH) for the efficient remediation of wastewater. Herein, we…”
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Role of gold and silver nanoparticles in cancer nano-medicine
Published in Artificial cells, nanomedicine, and biotechnology (01-01-2018)“…Development of nanoparticles (NPs) as a part of cancer therapeutics has given rise to a new field of research - cancer nanomedicine. In comparison to…”
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Mechanistic Interaction Study of Bromo-Noscapine with Bovine Serum Albumin employing Spectroscopic and Chemoinformatics Approaches
Published in Scientific reports (16-11-2018)“…Bromo-Noscapine (BrNs) is a tubulin-binding cytotoxic agent with significant activity against breast and lung cancer. The mechanistic interaction insight into…”
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Interaction of noscapine with human serum albumin (HSA): A spectroscopic and molecular modelling approach
Published in Journal of photochemistry and photobiology. A, Chemistry. (01-03-2019)“…The interaction of anticancer Noscapine hydrochloride (Nos) with human serum albumin has been studied by spectroscopic techniques and molecular docking…”
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Short-Term Steroid Treatment of Rhesus Macaque Increases Transduction
Published in Human gene therapy (01-02-2022)“…Repeat dosing poses a major hurdle for the development of an adeno-associated virus (AAV)-based gene therapy for cystic fibrosis, in part because of the…”
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Biological Evaluation of Noscapine analogues as Potent and Microtubule-Targeted Anticancer Agents
Published in Scientific reports (20-12-2019)“…In present investigation, an attempt was undertaken to modify the C-9 position of noscapine (Nos), an opium alkaloid to yield 9 -hydroxy methyl and 9…”
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Base-Free Suzuki-Miyaura Coupling Reaction Using Palladium
Published in Catalysis letters (01-06-2019)“…The carbon-carbon bond formation via Suzuki-Miyaura reaction was performed in water as green solvent. Pd(OAc).sub.2(PPh.sub.3).sub.2 supported on magnesium…”
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The Mitochondrial Ca2+ import complex is altered in ADPKD
Published in Cell calcium (Edinburgh) (01-01-2022)“…•ADPKD is associated with altered mitochondrial calcium uptake which fuels cyst growth.•87 characters. Mutations in either of the polycystic kidney disease…”
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Synthesis and characterization of novel 1,3-benzodioxole tagged noscapine based ionic liquids with in silico and in vitro cytotoxicity analysis on HeLa cells
Published in Journal of molecular liquids (15-03-2020)“…Ionic liquids (ILs) have proven themselves as a new class of anticancer compounds among the scientific community in the 21st century. With proven efficiency of…”
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