Search Results - "Varshney, Avanish K"

A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia by Varshney, Avanish K, Kuzmicheva, Galina A, Lin, Jian, Sunley, Kevin M, Bowling, Jr, Rodney A, Kwan, Tzu-Yu, Mays, Heather R, Rambhadran, Anu, Zhang, Yanfeng, Martin, Rebecca L, Cavalier, Michael C, Simard, John, Shivaswamy, Sushma

“…Staphylococcus aureus can cause devastating and life-threatening infections. With the increase in multidrug resistant strains, novel therapies are needed…”
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Detection and measurement of staphylococcal enterotoxin-like K (SEl-K) secretion by Staphylococcus aureus clinical isolates by Aguilar, Jorge L, Varshney, Avanish K, Wang, Xiaobo, Stanford, Lindsay, Scharff, Matthew, Fries, Bettina C

“…Staphylococcal enterotoxin-like K (SEl-K) is a potent mitogen that elicits T-cell proliferation and cytokine production at very low concentrations. However,…”
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Diverse Enterotoxin Gene Profiles among Clonal Complexes of Staphylococcus aureus Isolates from the Bronx, New York by Varshney, Avanish K, Mediavilla, José R, Robiou, Natalie, Guh, Alice, Wang, Xiabo, Gialanella, Philip, Levi, Michael H, Kreiswirth, Barry N, Fries, Bettina C

“…Staphylococcal enterotoxins (SE) can cause toxin-mediated disease, and those that function as superantigens are implicated in the pathogenesis of allergic…”
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Isotype switching increases efficacy of antibody protection against staphylococcal enterotoxin B-induced lethal shock and Staphylococcus aureus sepsis in mice by Varshney, Avanish K, Wang, Xiaobo, Aguilar, Jorge L, Scharff, Matthew D, Fries, Bettina C

“…Staphylococcal enterotoxin B (SEB) is a potent toxin that is produced by Staphylococcus aureus strains and is classified as a category B select agent. We have…”
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Methamphetamine Alters the Antimicrobial Efficacy of Phagocytic Cells during Methicillin-Resistant Staphylococcus aureus Skin Infection by Mihu, Mircea Radu, Roman-Sosa, Jessica, Varshney, Avanish K, Eugenin, Eliseo A, Shah, Bhavikkumar P, Ham Lee, Hiu, Nguyen, Long N, Guimaraes, Allan J, Fries, Bettina C, Nosanchuk, Joshua D, Martinez, Luis R

“…Methamphetamine (METH) is a major drug of abuse in the United States and worldwide. Furthermore, Staphylococcus aureus infections and METH use are coemerging…”
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Augmented Production of Panton-Valentine Leukocidin Toxin in Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Is Associated with Worse Outcome in a Murine Skin Infection Model by Varshney, Avanish K., Martinez, Luis R., Hamilton, Stephanie M., Bryant, Amy E., Levi, Michael H., Gialanella, Philip, Stevens, Dennis L., Fries, Bettina C.

“…The role of Panton-Valentine leukocidin (PVL) in Staphylococcus aureus infections is controversial. We used a mouse model of skin infection to compare the…”
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Frequency of Panton-Valentine Leukocidin-Producing Methicillin-Sensitive Staphylococcus Strains in Patients with Complicated Skin and Soft Tissue Infection in Bronx, New York by KALTSAS, Anna, GUH, Alice, MEDIAVILLA, José R, VARSHNEY, Avanish K, ROBIOU, Natalie, GIALANELLIA, Philip, HENRY, Michael, LEVI, Michael H, FRIES, Bettina C

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mechanisms Mediating Enhanced Neutralization Efficacy of Staphylococcal Enterotoxin B by Combinations of Monoclonal Antibodies by Dutta, Kaushik, Varshney, Avanish K., Franklin, Matthew C., Goger, Michael, Wang, Xiaobo, Fries, Bettina C.

“…Staphylococcal enterotoxin B (SEB) is a superantigen that cross-links the major histocompatibility complex class II and specific V-β chains of the T-cell…”
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Monoclonal antibodies protect from Staphylococcal Enterotoxin K (SEK) induced toxic shock and sepsis by USA300 Staphylococcus aureus by Aguilar, Jorge L., Varshney, Avanish K., Pechuan, Ximo, Dutta, Kaushik, Nosanchuk, Joshua D., Fries, Bettina C.

“…Staphylococcus aureus is a leading infectious cause of life-threatening disease in humans, yet there is currently no vaccine to combat this bacterium. The…”
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Staphylococcal Enterotoxin B-Specific Monoclonal Antibody 20B1 Successfully Treats Diverse Staphylococcus aureus Infections by Varshney, Avanish K., Wang, Xiaobo, Scharff, Matthew D., MacIntyre, Jennifer, Zollner, Richard S., Kovalenko, Oleg V., Martinez, Luis R., Byrne, Fergus R., Fries, Bettina C.

“…Background. Methicillin-resistant Staphylococcus aureus (MRSA) has become a major health threat in the United States. Staphylococcal enterotoxin B (SEB) is a…”
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Humanized Staphylococcal Enterotoxin B (SEB)-Specific Monoclonal Antibodies Protect From SEB Intoxication and Staphylococcus aureus Infections Alone or as Adjunctive Therapy With Vancomycin by Varshney, Avanish K., Wang, Xiaobo, MacIntyre, Jennifer, Zollner, Richard S., Kelleher, Kerry, Kovalenko, Oleg V., Pechuan, Ximo, Byrne, Fergus R., Fries, Bettina C.

“…Background. Staphylococcal enterotoxin B (SEB), a potential biological warfare agent, is a potent superantigen that contributes to the virulence of…”
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An optimal antitumor response by a novel CEA/CD3 bispecific antibody for colorectal cancers by Wang, Ninghai, Patel, Harshal, Schneider, Irene C, Kai, Xin, Varshney, Avanish K, Zhou, Li

“…Abstract Background CD3-based bispecific T cell engagers (bsTCEs) are one of the most promising bispecific antibodies for effective cancer treatments. To…”
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Generation, Characterization, and Epitope Mapping of Neutralizing and Protective Monoclonal Antibodies against Staphylococcal Enterotoxin B-induced Lethal Shock by Varshney, Avanish K., Wang, Xiaobo, Cook, Emily, Dutta, Kaushik, Scharff, Matthew D., Goger, Michael J., Fries, Bettina C.

“…T-cell stimulating activity of Staphylococcal enterotoxin B (SEB) is an important factor in the pathogenesis of certain staphylococcal diseases including SEB…”
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ALL2, a Homologue of ALL1, Has a Distinct Role in Regulating pH Homeostasis in the Pathogen Cryptococcus neoformans by Jain, Neena, Bouklas, Tejas, Gupta, Anjali, Varshney, Avanish K, Orner, Erika P, Fries, Bettina C

“…Cryptococcus neoformans is a facultative intracellular fungal pathogen that has a polysaccharide capsule and causes life-threatening meningoencephalitis. Its…”
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Optimal irrigation and debridement of infected joint implants: an in vitro methicillin-resistant Staphylococcus aureus biofilm model by Schwechter, Evan M, Folk, David, Varshney, Avanish K, Fries, Bettina C, Kim, Sun Jin, Hirsh, David M

“…Acute postoperative and acute, late hematogenous prosthetic joint infections have been treated with 1-stage irrigation and debridement with polyethylene…”
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Optimization of experimental conditions for functional in vitro characterization of humanized antibodies specific for staphylococcal enterotoxin B by MacIntyre, Jennifer L., Varshney, Avanish K., Wang, Xiaobo, Gatto, Scott, Friedman, Clarence, Liu, Yan, Kerns, Kelvin, Kovalenko, Oleg, Adkins, Karissa, Zollner, Richard, Fries, Bettina C., Byrne, Fergus R.

“…Staphylococcus aureus is a common nosocomial infection and its resistance to penicillin and methicillin antibiotics is a growing clinical problem. We…”
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Optimal Irrigation and Debridement of Infected Joint Implants by Schwechter, Evan M., MD, Folk, David, BA, Varshney, Avanish K., PhD, Fries, Bettina C., MD, Kim, Sun Jin, MD, Hirsh, David M., MD

“…Abstract Acute postoperative and acute, late hematogenous prosthetic joint infections have been treated with 1-stage irrigation and debridement with…”
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Association of Mycoplasma pneumoniae and asthma among Indian children by Varshney, Avanish K., Chaudhry, Rama, Saharan, Sunil, Kumar Kabra, Sushil, Dhawan, Benu, Dar, Lalit, Malhotra, Pawan

“…Abstract The role of Mycoplasma pneumoniae infection as a trigger for asthma exacerbations is well supported in previous studies. This study was designed to…”
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Abstract 1864: An improved trispecific antibody (TsAb) platform for optimally engaging T cells for the treatment of solid tumor malignancies by Nair, Reshmi, Somasundaram, Veena, Goswami, Arvind, Bhatnagar, Jaya, Paul, Sourav, Dey, Chaitali, Vaidyanathan, Kalyanaraman, Paul, Rajkumar, Periasamy, Sankar, KG, Mary Helen, NV, Mahalakshmi, Sinha, Abhishek, Salazar, Rachel, Varshney, Avanish K.

“…Abstract T-cell recruiting bispecific antibodies have been shown to be clinically effective in treating hematological malignancies. However, their application…”
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Generation, characterization, and epitope mapping of neutralizing and protective monoclonal antibodies against Staphylococcal enterotoxin B-induced lethal shock by Varshney, Avanish K., Wang, Xiaobo, Cook, Emily, Dutta, Kaushik, Scharff, Matthew D., Goger, Michael J., Fries, Bettina C.

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