Search Results - "Varshavsky, Alexander D"

Hierarchical Modeling of Phenolic Ligand Binding to 2Zn−Insulin Hexamers by Birnbaum, Duane T, Dodd, Steven W, Saxberg, Bo E. H, Varshavsky, Alexander D, Beals, John M

“…Phenolic ligands, e.g., phenol and m-cresol, bind to 2Zn(II)−insulin hexamers and induce a conformational change at the N-terminus of the B-chain for each…”
Get full text

Global stochastic optimization in hierarchical modeling of ligand protein binding profiles by Varshavsky, Alexander D, Birnbaum, Duane T, Beals, John M, Saxberg, Bo E

“…We present a detailed explanation of a mathematical method and numerical technique applied to solve an irregular non-linear fitting problem that results from…”
Get full text

Serine 228 is essential for catalytic activities of 85-kDa cytosolic phospholipase A2 by Sharp, J D, Pickard, R T, Chiou, X G, Manetta, J V, Kovacevic, S, Miller, J R, Varshavsky, A D, Roberts, E F, Strifler, B A, Brems, D N

“…The Ca(2+)-sensitive cytosolic phospholipase A2 (cPLA2) displays both a phospholipase A2 and a lysophospholipase activity. Numerous hydrolases, including…”
Get full text

Visualization and comparison of molecular dynamics simulations of leukotriene C4, leukotriene D4, and leukotriene E4 by Herron, D K, Bollinger, N G, Chaney, M O, Varshavsky, A D, Yost, J B, Sherman, W R, Thingvold, J A

“…Molecular dynamics simulations of leukotriene C4 (LTC4), leukotriene D4 (LTD4), and leukotriene E4 (LTE4) were carried out, and the data were visualized in an…”
Get full text