Search Results - "Varotsis, Constantinos"

Modifications of hemoglobin and myoglobin by Maillard reaction products (MRPs) by Ioannou, Aristos, Varotsis, Constantinos

“…High performance liquid chromatography (HPLC) coupled with a Fraction Collector was employed to isolate Maillard reaction products (MRPs) formed in model…”
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Nitric oxide activation by caa3 oxidoreductase from Thermus thermophilus by Ohta, Takehiro, Soulimane, Tewfik, Kitagawa, Teizo, Varotsis, Constantinos

“…Visible and UV-resonance Raman spectroscopy was employed to investigate the reaction of NO with cytochrome caa3 from Thermus thermophilus. We show the…”
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ns-μs Time-Resolved Step-Scan FTIR of ba₃ Oxidoreductase from Thermus thermophilus: Protonic Connectivity of w941-w946-w927 by Nicolaides, Antonis, Soulimane, Tewfik, Varotsis, Constantinos

“…Time-resolved step-scan FTIR spectroscopy has been employed to probe the dynamics of the ₃ oxidoreductase from in the ns-μs time range and in the pH/pD 6-9…”
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Nitric oxide activation and reduction by heme–copper oxidoreductases and nitric oxide reductase by Pinakoulaki, Eftychia, Varotsis, Constantinos

“…The understanding of the dynamics and conformational control involved in the interplay between structure and function of nitric oxide reductase (Nor) and…”
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Bacterial Colonization on the Surface of Copper Sulfide Minerals Probed by Fourier Transform Infrared Micro-Spectroscopy by Varotsis, Constantinos, Papageorgiou, Marios, Tselios, Charalampos, Yiannakkos, Konstantinos A., Adamou, Anastasia, Nicolaides, Antonis

“…Biofilm formation is a molecular assembly process occurring at interfaces, such as in bioleaching processes. The real time monitoring of the marker bands of…”
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The Structure of the Hyponitrite Species in a Heme FeCu Binuclear Center by Varotsis, Constantinos, Ohta, Takehiro, Kitagawa, Teizo, Soulimane, Tewfik, Pinakoulaki, Eftychia

“…NO laughing matter: The enzymatic production of laughing gas (N2O) from two molecules of NO requires the formation of the NN bond and the subsequent cleavage…”
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The Protein Effect in the Structure of Two Ferryl-Oxo Intermediates at the Same Oxidation Level in the Heme Copper Binuclear Center of Cytochrome c Oxidase by Pinakoulaki, Eftychia, Daskalakis, Vangelis, Ohta, Takehiro, Richter, Oliver-Matthias H., Budiman, Kerstin, Kitagawa, Teizo, Ludwig, Bernd, Varotsis, Constantinos

“…Identification of the intermediates and determination of their structures in the reduction of dioxygen to water by cytochrome c oxidase (CcO) are particularly…”
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Binding and Docking Interactions of NO, CO and O2 in Heme Proteins as Probed by Density Functional Theory by Daskalakis, Vangelis, Varotsis, Constantinos

“…Dynamics and reactivity in heme proteins include direct and indirect interactions of the ligands/substrates like CO, NO and O2 with the environment. Direct…”
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Resonance Raman Spectroscopy of Nitric Oxide Reductase and cbb3 Heme-Copper Oxidase by PINAKOULAKI, Eftychia, VAROTSIS, Constantinos

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The origin of the FeIV=O intermediates in cytochrome aa3 oxidase by Pinakoulaki, Eftychia, Daskalakis, Vangelis, Varotsis, Constantinos

“…The dioxygen reduction mechanism in cytochrome oxidases relies on proton control of the electron transfer events that drive the process. Proton delivery and…”
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Metal (Ag/Ti)-Containing Hydrogenated Amorphous Carbon Nanocomposite Films with Enhanced Nanoscratch Resistance: Hybrid PECVD/PVD System and Microstructural Characteristics by Constantinou, Marios, Nikolaou, Petros, Koutsokeras, Loukas, Avgeropoulos, Apostolos, Moschovas, Dimitrios, Varotsis, Constantinos, Patsalas, Panos, Kelires, Pantelis, Constantinides, Georgios

“…This study aimed to develop hydrogenated amorphous carbon thin films with embedded metallic nanoparticles (a-C:H:Me) of controlled size and concentration…”
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Assigning Vibrational Spectra of Ferryl-Oxo Intermediates of Cytochrome c Oxidase by Periodic Orbits and Molecular Dynamics by Daskalakis, Vangelis, Farantos, Stavros C, Varotsis, Constantinos

“…Complexity is inherent in biological molecules not only because of the large number of atoms but also because of their nonlinear interactions responsible for…”
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Probing the Q-proton pathway of ba3-cytochrome c oxidase by time-resolved Fourier transform infrared spectroscopy by Koutsoupakis, Constantinos, Soulimane, Tewfik, Varotsis, Constantinos

“…In cytochrome c oxidase, the terminal respiratory enzyme, electron transfers are strongly coupled to proton movements within the enzyme. Two proton pathways (K…”
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Two Ligand-Binding Sites in the O₂-Sensing Signal Transducer HemAT: Implications for Ligand Recognition/Discrimination and Signaling by Pinakoulaki, Eftychia, Yoshimura, Hideaki, Daskalakis, Vangelis, Yoshioka, Shiro, Aono, Shigetoshi, Varotsis, Constantinos

“…We have identified a ligand (CO) accommodation cavity in the signal transducer sensor protein HemAT (heme-based aerotactic transducer) that allows us to gain…”
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Vibrational Resonances and CuB Displacement Controlled by Proton Motion in Cytochrome c Oxidase by Daskalakis, Vangelis, Farantos, Stavros C, Guallar, Victor, Varotsis, Constantinos

“…Cytochrome c oxidase (CcO), found in the inner mitochondrial membranes or in many bacteria, catalyzes the four-electron reduction of molecular oxygen to water…”
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Ligand Binding in a Docking Site of Cytochrome c Oxidase:  A Time-Resolved Step-Scan Fourier Transform Infrared Study by Koutsoupakis, Constantinos, Soulimane, Tewfik, Varotsis, Constantinos

“…The description of reaction regulation in enzymes responsible for activating and catalyzing small molecules (O2, NO) requires identification of ligand movement…”
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The Role of the Cross-link His-Tyr in the Functional Properties of the Binuclear Center in Cytochrome c Oxidase by Pinakoulaki, Eftychia, Pfitzner, Ute, Ludwig, Bernd, Varotsis, Constantinos

“…Resonance Raman and Fourier transform infrared spectroscopies have been used to study theaa3-type cytochrome c oxidase and the Y280H mutant from Paracoccus…”
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Evidence for reversible light-dependent transitions in the photosynthetic pigments of diatoms by Tselios, Charalampos, Varotsis, Constantinos

“…Marine diatoms contribute to oxygenic photosynthesis and carbon fixation and handle large changes under variable light intensity on a regular basis. The unique…”
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Direct Detection of Fe(IV)=O Intermediates in the Cytochrome aa3 Oxidase from Paracoccus denitrificans/H2O2 Reaction by Pinakoulaki, Eftychia, Pfitzner, Ute, Ludwig, Bernd, Varotsis, Constantinos

“…We report the first evidence for the formation of the “607- and 580-nm forms” in the cytochrome oxidase aa3/H2O2 reaction without the involvement of tyrosine…”
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Docking Site Dynamics of ba3-Cytochrome c Oxidase from Thermus thermophilus by Koutsoupakis, Constantinos, Soulimane, Tewfik, Varotsis, Constantinos

“…Ligand trajectories trapped within a docking site or within an internal cavity near the active site of proteins are important issues toward the elucidation of…”
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