Search Results - "Varnavski, A N"

Evaluation of toxicity from high-dose systemic administration of recombinant adenovirus vector in vector-naïve and pre-immunized mice by VARNAVSKI, A. N, CALCEDO, R, BOVE, M, GAO, G, WILSON, J. M

“…Toxicity associated with in vivo administration of adenovirus (Ad) vectors has been linked to activation of both innate and adaptive immune responses…”
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Coupling between Replication and Packaging of Flavivirus RNA: Evidence Derived from the Use of DNA-Based Full-Length cDNA Clones of Kunjin Virus by Khromykh, A A, Varnavski, A N, Sedlak, P L, Westaway, E G

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The influence of polyetherimide on gelation and phase separation in epoxy systems by Rodin, D. L., Varnavski, A. N., Stefanovich, S. Yu, Yablokova, M. Yu

“…In the process of curing under thermostatic conditions, the time dependence of active and reactive components of the dielectric permittivity of epoxy amine…”
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Activation of Innate Immunity in Nonhuman Primates Following Intraportal Administration of Adenoviral Vectors by Schnell, M A, Zhang, Y, Tazelaar, J, Gao, G P, Yu, Q C, Qian, R, Chen, S J, Varnavski, A N, LeClair, C, Raper, S E, Wilson, J M

“…The innate immune response to intraportally infused adenoviral vector was evaluated in rhesus monkeys. A first-generation adenovirus-expressing lacZ (Ad-lacZ)…”
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Stable High-Level Expression of Heterologous Genes In Vitro and In Vivo by Noncytopathic DNA-Based Kunjin Virus Replicon Vectors by Varnavski, A N, Young, P R, Khromykh, A A

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Encapsidation of the Flavivirus Kunjin Replicon RNA by Using a Complementation System Providing Kunjin Virus Structural Proteins in trans by Khromykh, A A, Varnavski, A N, Westaway, E G

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Noncytopathic Flavivirus Replicon RNA-Based System for Expression and Delivery of Heterologous Genes by Varnavski, Andrei N., Khromykh, Alexander A.

“…Noncytopathic replicons of the flavivirus Kunjin (KUN) were employed for expression and delivery of heterologous genes. Replicon vector C20DX2Arep, containing…”
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Preexisting Immunity to Adenovirus in Rhesus Monkeys Fails To Prevent Vector-Induced Toxicity by Varnavski, Andrei N, Zhang, Yi, Schnell, Michael, Tazelaar, John, Louboutin, Jean-Pierre, Yu, Qian-Chun, Bagg, Adam, Gao, Guang-ping, Wilson, James M

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Efficient transduction of human monocyte-derived dendritic cells by chimpanzee-derived adenoviral vector by Varnavski, Andrei N, Schlienger, Katia, Bergelson, Jeffrey M, Gao, Guang-Ping, Wilson, James M

“…Using recombinant adenoviruses (Ads) to target host dendritic cells (DCs) presents an attractive prospect for immunization. The efficacy of commonly used human…”
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