Search Results - "Varma, Tushar"

The Toll-Like Receptor 4 Agonist Monophosphoryl Lipid A Augments Innate Host Resistance to Systemic Bacterial Infection by ROMERO, Christopher D, VARMA, Tushar K, HOBBS, Jason B, REYES, Aimee, DRIVER, Brandon, SHERWOOD, Edward R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Using Social Media for Peer-to-Peer Cancer Support: Interviews With Young Adults With Cancer by Lazard, Allison J, Collins, Meredith K Reffner, Hedrick, Ashley, Varma, Tushar, Love, Brad, Valle, Carmina G, Brooks, Erik, Benedict, Catherine

“…Background: Web-based social support can address social isolation and unmet support needs among young adults with cancer (aged 18-39 years). Given that 94% of…”
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Effects of aging on mortality, hypothermia, and cytokine induction in mice with endotoxemia or sepsis by Saito, Hiroshi, Sherwood, Edward R, Varma, Tushar K, Evers, B.Mark

“…Aging is accompanied by an altered stress response that underlies increased susceptibility of the elderly patients to physiological stress such as infection…”
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Improved bacterial clearance and decreased mortality can be induced by LPS tolerance and is not dependent upon IFN-gamma by Murphey, E D, Fang, Geping, Varma, Tushar K, Sherwood, Edward R

“…Endotoxin (LPS) tolerance is induced by exposure to sublethal doses of LPS, resulting in a suppressed proinflammatory response and an improved survival rate…”
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Endotoxin-induced gamma interferon production: contributing cell types and key regulatory factors by Varma, Tushar K, Lin, Cheng Y, Toliver-Kinsky, Tracy E, Sherwood, Edward R

“…Gamma interferon (IFN-gamma) is an important mediator of endotoxin (lipopolysaccharide [LPS])-induced immune responses. However, the specific cell types that…”
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Endotoxin Priming Improves Clearance of Pseudomonas aeruginosa in Wild-Type and Interleukin-10 Knockout Mice by Varma, Tushar K, Durham, Megan, Murphey, Erle D, Cui, Weihua, Huang, Zhiyu, Lin, Cheng Y, Toliver-Kinsky, Tracy, Sherwood, Edward R

“…Endotoxin (lipopolysaccharide [LPS]) tolerance is an altered state of immunity caused by prior exposure to LPS, in which production of many cytokines,…”
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β2 Microglobulin knockout mice are resistant to lethal intraabdominal sepsis by SHERWOOD, Edward R, LIN, Cheng Y, WEIKE TAO, HARTMANN, Christopher A, DUJON, Jay E, FRENCH, Andrew J, VARMA, Tushar K

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Cellular Mechanisms That Cause Suppressed Gamma Interferon Secretion in Endotoxin-Tolerant Mice by VARMA, Tushar K, TOLIVER-KINSKY, Tracy E, LIN, Cheng Y, KOUTROUVELIS, Aristides P, NICHOLS, Joan E, SHERWOOD, Edward R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Differential effect of imipenem treatment on wild-type and NK cell-deficient CD8 knockout mice during acute intra-abdominal injury by Enoh, Victor T, Fairchild, Chad D, Lin, Cheng Y, Varma, Tushar K, Sherwood, Edward R

“…CD8 knockout mice depleted of natural killer (NK) cells by treatment with anti-asialoGM1 (CD8KO/alphaAsGM1 mice) are resistant to injury caused by cecal…”
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Interferon-γ production is suppressed in thermally injured mice: Decreased production of regulatory cytokines and corresponding receptors by TOLIVER-KINSKY, Tracy E, VARMA, Tushar K, LIN, Cheng Y, HERNDON, David N, SHERWOOD, Edward R

“…Thermal injury to 40% or more of the total body surface area poses a significant risk for the development of opportunistic infections that increase…”
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Left ventricular diastolic filling characteristics are not impaired but systolic performance was augmented in the early hours of experimental endotoxemia in humans by MATHRU, Mali, POLLARD, Valerie, HE, Gy, VARMA, Tushar K, AHMAD, Masood, PROUGH, Donald S

“…This study was performed to determine whether endotoxemia causes diastolic cardiac dysfunction. Eleven healthy volunteers, 30 +/- 6 years of age, underwent…”
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Effect of transforming growth factor-β neutralization on survival and bacterial clearance in a murine model of Pseudomonas aeruginosa burn wound infection by ZHIYU HUANG, PEREIRA, Clifford, TOLIVER-KINSKY, Tracy, MURPHEY, Erle D, VARMA, Tushar K, LIN, Cheng Y, HERNDON, David N, SHERWOOD, Edward R

“…Transforming growth factor-beta (TGF-beta), a cytokine with anti-inflammatory properties, may contribute to postburn immunosuppression. This study was designed…”
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Protein kinase C-dependent phosphorylation and mitochondrial translocation of aldose reductase by Varma, Tushar, Liu, Si-Qi, West, Matthew, Thongboonkerd, Visith, Ruvolo, Peter P., May, W.Stratford, Bhatnagar, Aruni

“…Although aldose reductase (AR) is a critical participant in osmoregulation, and the metabolism of glucose and aldehydes derived from lipid peroxidation,…”
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Initiation and changes in use of social media for peer support among young adult cancer patients and survivors by Lazard, Allison J., Collins, Meredith K. Reffner, Hedrick, Ashley, Horrell, Lindsey N., Varma, Tushar, Love, Brad, Valle, Carmina G., Benedict, Catherine

“…Purpose Social isolation is a prominent challenge for many young adults with cancer. Despite desires for peer‐to‐peer connections through technology, little is…”
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Glucan phosphate potentiates endotoxin-induced interferon-gamma expression in immunocompetent mice, but attenuates induction of endotoxin tolerance by Sherwood, E R, Varma, T K, Fram, R Y, Lin, C Y, Koutrouvelis, A P, Toliver-Kinsky, T E

“…Glucan phosphate has been shown to enhance antimicrobial immunity in a variety of experimental models. However, the mechanisms by which glucans enhance…”
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A multimeric model for murine anti-apoptotic protein Bcl-2 and structural insights for its regulation by post-translational modification by Mathura, Venkatarajan S, Soman, Kizhake V, Varma, Tushar K, Braun, Werner

“…A monomeric model for murine antiapoptotic protein Bcl-2 was constructed by comparative modeling with the software suite MPACK (EXDIS/DIAMOD/FANTOM) using…”
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'It's Nothing Like Cancer': Young Adults with Cancer Reflect on Memorable Entertainment Narratives by Reffner Collins, Meredith K., Lazard, Allison J., Hedrick McKenzie, Ashley M., Varma, Tushar

“…A cancer diagnosis in young adulthood disrupts the achievement of developmental milestones, and young adults struggle to make sense of their cancer experience…”
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MICE DEPLETED OF αβ BUT NOT γδ T CELLS ARE RESISTANT TO MORTALITY CAUSED BY CECAL LIGATION AND PUNCTURE by Enoh, Victor T., Lin, Scott H., Lin, Cheng Y., Toliver-Kinsky, Tracy, Murphey, Erle D., Varma, Tushar K., Sherwood, Edward R.

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Differential effect of imipenem treatment on injury caused by cecal ligation and puncture in wild-type and NK cell-deficient beta(2)-microgloblin knockout mice by Enoh, Victor T, Lin, Cheng Y, Varma, Tushar K, Sherwood, Edward R

“…Our previous studies showed that beta(2)-microglobulin knockout mice treated with anti-asialoGM1 (beta2MKO/alphaAsGM1 mice) are resistant to injury caused by…”
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Mice depleted of alphabeta but not gammadelta T cells are resistant to mortality caused by cecal ligation and puncture by Enoh, Victor T, Lin, Scott H, Lin, Cheng Y, Toliver-Kinsky, Tracy, Murphey, Erle D, Varma, Tushar K, Sherwood, Edward R

“…The present study was undertaken to determine whether the mice depleted of alphabeta or gammadelta T cells show resistance to acute polymicrobial sepsis caused…”
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