Search Results - "Varma, MV"

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  1. 1
    Transporter‐Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug–Drug Interactions of Montelukast

    Transporter‐Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug–Drug Interactions of Montelukast by Varma, MV, Kimoto, E, Scialis, R, Bi, Y, Lin, J, Eng, H, Kalgutkar, AS, El‐Kattan, AF, Rodrigues, AD, Tremaine, LM

    Published in Clinical pharmacology and therapeutics (01-03-2017)
    “…Montelukast, a leukotriene receptor antagonist commonly prescribed for treatment of asthma, is primarily metabolized by cytochrome P450 (CYP)2C8, and has been…”
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  2. 2
    Extended Clearance Classification System (ECCS) informed approach for evaluating investigational drugs as substrates of drug transporters

    Extended Clearance Classification System (ECCS) informed approach for evaluating investigational drugs as substrates of drug transporters by Varma, MV, El‐Kattan, AF, Feng, B, Steyn, SJ, Maurer, TS, Scott, DO, Rodrigues, AD, Tremaine, LM

    Published in Clinical pharmacology and therapeutics (01-07-2017)
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  3. 3
    Quantitative Prediction of Drug–Drug Interactions Involving Inhibitory Metabolites in Drug Development: How Can Physiologically Based Pharmacokinetic Modeling Help?

    Quantitative Prediction of Drug–Drug Interactions Involving Inhibitory Metabolites in Drug Development: How Can Physiologically Based Pharmacokinetic Modeling Help? by Templeton, IE, Chen, Y, Mao, J, Lin, J, Yu, H, Peters, S, Shebley, M, Varma, MV

    “…This subteam under the Drug Metabolism Leadership Group (Innovation and Quality Consortium) investigated the quantitative role of circulating inhibitory…”
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  4. 4
    Response to “Quantitative Prediction of Drug‐Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is It Worth?”

    Response to “Quantitative Prediction of Drug‐Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is It Worth?” by Templeton, IE, Chen, Y, Mao, J, Lin, J, Yu, H, Peters, S, Shebley, M, Varma, MV

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  5. 5
    Functional Role of P-Glycoprotein in Limiting Intestinal Absorption of Drugs:  Contribution of Passive Permeability to P-Glycoprotein Mediated Efflux Transport

    Functional Role of P-Glycoprotein in Limiting Intestinal Absorption of Drugs:  Contribution of Passive Permeability to P-Glycoprotein Mediated Efflux Transport by Varma, Manthena V. S, Sateesh, Khandavilli, Panchagnula, Ramesh

    Published in Molecular pharmaceutics (01-01-2005)
    “…The aim of the present study is to evaluate the quantitative contribution of passive permeability to P-glycoprotein-mediated (P-gp-mediated) efflux and the…”
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  6. 6
    Smart Home Application for Challenged Along with Human Temperature Detector

    Smart Home Application for Challenged Along with Human Temperature Detector by Beena Bethel, G.N., Reddy, M. Sai Rohith, Kushaal Varma, M.V., Vamshi, D Sai, Stephen, P.

    “…A smart home is a component of the Internet of Things (IoT) technology implementations that help people with their daily activities. To link devices to the…”
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