Search Results - "Varkey, Aditi"
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Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity
Published in Nature communications (24-03-2023)“…During intracellular infection, T follicular helper (T FH ) and T helper 1 (T H 1) cells promote humoral and cell-mediated responses, respectively. Another…”
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2
Aiolos restrains acquisition of a cytotoxic program by CD4 +T cells
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract CD4 +cytotoxic T lymphocytes, or CD4-CTLs, comprise a CD4 +subset capable of performing functions normally observed in CD8 +T and Natural Killer…”
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3
Hypoxia promotes cytolytic activity of CD8 T cells and pathogenesis in cutaneous leishmaniasis
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract Leishmaniasis is a disease caused by protozoan parasites of the genus Leishmania and the most common form of the disease is cutaneous leishmaniasis…”
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4
Neutrophil-mediated hypoxia drives pathogenic [CD8.sup.+] T cell responses in cutaneous leishmaniasis
Published in The Journal of clinical investigation (15-07-2024)“…Cutaneous leishmaniasis caused by Leishmania parasites exhibits a wide range of clinical manifestations. Although parasites influence disease severity,…”
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5
Type 3 Innate Lymphoid Cells Protect Leukemic Blasts from Natural Killer Cell Cytotoxicity in Acute Myeloid Leukemia
Published in Blood (15-11-2022)Get full text
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6
Neutrophil-mediated hypoxia drives pathogenic CD8 T cell responses in cutaneous leishmaniasis
Published in The Journal of clinical investigation (15-07-2024)“…Cutaneous leishmaniasis caused by Leishmania parasites exhibits a wide range of clinical manifestations. Although parasites influence disease severity,…”
Get full text
Journal Article -
7
Aiolos represses CD4 + T cell cytotoxic programming via reciprocal regulation of T FH transcription factors and IL-2 sensitivity
Published in Nature communications (24-03-2023)“…During intracellular infection, T follicular helper (T ) and T helper 1 (T 1) cells promote humoral and cell-mediated responses, respectively. Another subset,…”
Get full text
Journal Article