Search Results - "Varjosaari, Sami"

Chiral Brønsted Acid-Catalyzed Metal-Free Asymmetric Direct Reductive Amination Using 1‑Hydrosilatrane by Skrypai, Vladislav, Varjosaari, Sami E, Azam, Fawwaz, Gilbert, Thomas M, Adler, Marc J

“…The asymmetric direct reductive amination of prochiral ketones with aryl amines using 1-hydrosilatrane with a chiral Brønsted acid catalyst is reported. This…”
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Simple Metal‐Free Direct Reductive Amination Using Hydrosilatrane to Form Secondary and Tertiary Amines by Varjosaari, Sami E., Skrypai, Vladislav, Suating, Paolo, Hurley, Joseph J. M., Lio, Ashley M. De, Gilbert, Thomas M., Adler, Marc J.

“…This work describes the use of cheap, safe, and easy‐to‐handle hydrosilatrane as the reductant in direct reductive amination reactions. This efficient method…”
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1‐Hydrosilatrane: A Locomotive for Efficient Ketone Reductions by Varjosaari, Sami E., Skrypai, Vladislav, Suating, Paolo, Hurley, Joseph J. M., Gilbert, Thomas M., Adler, Marc J.

“…An efficient method for the reduction of ketones with 1‐hydrosilatrane is described. In the presence of a Lewis base activator, the resulting secondary…”
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Front Cover: 1‐Hydrosilatrane: A Locomotive for Efficient Ketone Reductions (Eur. J. Org. Chem. 2/2017) by Varjosaari, Sami E., Skrypai, Vladislav, Suating, Paolo, Hurley, Joseph J. M., Gilbert, Thomas M., Adler, Marc J.

“…The cover picture shows artist Jesse Mai's imagination of the reduction of ketones to alcohols by 1‐hydrosilatrane. The accompanying work describes this mild…”
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Stereoelectronics of silyloxybenzoic acids by Varjosaari, Sami E., Hess, Jeremy P., Suating, Paolo, Price, John M., Gilbert, Thomas M., Adler, Marc J.

“…[Display omitted] Synthetic organic chemists generally think of silyl ethers as easier-to-cleave alkyl ethers, frequently neglecting to consider both the…”
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One-Pot Reductive Acetylation of Aldehydes using 1-Hydrosilatrane in Acetic Acid by James, Reuben, Herlugson, Sharon, Varjosaari, Sami, Skrypai, Vladislav, Shakeel, Zainab, Gilbert, Thomas, Adler, Marc

“…A one-pot, direct reductive acetylation of aldehydes was achieved under mild conditions using 1-hydrosilatrane as a safe and easily accessible catalyst…”
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Computational investigation of the effect of alkoxy carbon substitution on the mechanism of carbonyl group reduction by 1-hydridosilatranes by Pixler, Alexander S., DeLio, Ashley M., Varjosaari, Sami E., Skrypai, Vladislav, Adler, Marc J., Gilbert, Thomas M.

“…•Computational studies of reduction of acetone by 1-hydridosilatranes show sizably exergonic formation of dialkoxides, in agreement with experiment.•Reductions…”
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Enantioselective metal-free reduction of ketones by a user-friendly silane with a reusable chiral additive by Varjosaari, Sami E., Skrypai, Vladislav, Herlugson, Sharon M., Gilbert, Thomas M., Adler, Marc J.

“…[Display omitted] •Asymmetric reduction of ketones using easy-to-handle and inexpensive silatrane.•Commercially available 1,2-aminoalcohols served to induce…”
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Reduction of Ketones to Alcohols and Tertiary Amines Using 1-Hydrosilatrane by Varjosaari, Sami Ensio

“…1-Hydrosilatrane is an easily synthesized, stable, solid silane which can be made into an efficient reducing agent in the presence of a Lewis base, by taking…”
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