Search Results - "Varghese, Z"

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    CD36 and lipid metabolism in the evolution of atherosclerosis by Zhao, Lei, Varghese, Z, Moorhead, J F, Chen, Yaxi, Ruan, Xiong Z

    Published in British medical bulletin (01-06-2018)
    “…Abstract Background CD36 is a multi-functional class B scavenger receptor, which acts as an important modulator of lipid homeostasis and immune responses…”
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    Journal Article
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    Inflammatory stress reduces the effectiveness of statins in the kidney by disrupting HMGCoA reductase feedback regulation by Chen, Yaxi, Zhao, Lei, Li, Qing, Wheeler, David C, Varghese, Zac, Moorhead, John F, Powis, Stephen H, Ruan, Xiong Z

    Published in Nephrology, dialysis, transplantation (01-10-2014)
    “…Patients with chronic kidney disease (CKD) are unlikely to gain the same benefit from conventional doses of statins as do patients with cardiovascular disease…”
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    Dysregulation of LDL receptor under the influence of inflammatory cytokines: A new pathway for foam cell formation by RUAN, Xiong Z, VARGHESE, Zac, POWIS, Stephen H, MOORHEAD, John F

    Published in Kidney international (01-11-2001)
    “…Lipid-mediated renal injury is an important component of glomerulosclerosis and its similarity to atherosclerosis is well described. This study focused on the…”
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    Does oral folic acid lower total homocysteine levels and improve endothelial function in children with chronic renal failure? by BENNETT-RICHARDS, K, KATTENHORN, M, DONALD, A, OAKLEY, G, VARGHESE, Z, REES, L, DEANFIELD, J. E

    Published in Circulation (New York, N.Y.) (16-04-2002)
    “…Accelerated vascular disease is common in chronic renal failure (CRF) and accounts for significant mortality and morbidity. Elevated homocysteine levels may…”
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    The PPARα ligand fenofibrate: meeting multiple targets in diabetic nephropathy by Varghese, Z., Moorhead, J.F., Ruan, X.Z.

    Published in Kidney international (01-05-2006)
    “…Fibrate peroxisome proliferator-activated receptor (PPAR)-α ligands are mainly used as hypolipidemic drugs. But this commentary highlights their potential in…”
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    Regulation of lipoprotein trafficking in the kidney: role of inflammatory mediators and transcription factors by Ruan, X Z, Moorhead, J F, Fernando, R, Wheeler, D C, Powis, S H, Varghese, Z

    Published in Biochemical Society transactions (01-02-2004)
    “…Inflammation and dyslipidaemia both play important roles in the development of glomerular atherosclerosis in renal diseases. We have demonstrated that…”
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    Acute transplant rejection induced by blood transfusion reaction to the Kidd blood group system by Holt, Stephen, Donaldson, Helen, Hazlehurst, Geoffrey, Varghese, Zac, Contreras, Marcela, Kingdon, Edward, Sweny, Paul, Burns, Aine

    Published in Nephrology, dialysis, transplantation (01-09-2004)
    “…Many renal transplant centres now try to avoid blood transfusion prior to renal transplantation, to avoid alloimmunization due to antibody production against…”
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    Nitric oxide production by human peritoneal mesothelial cells by Davenport, A, Fernando, R L, Robson, R, Varghese, Z

    Published in International journal of artificial organs (01-01-2004)
    “…Nitric oxide (NO) has multiple actions, ranging from immunomodulation to regulation of vascular tone and capillary flow. Thus NO generation within the…”
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    EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-γ–dependent mechanism by Li, Hang, Ruan, Xiong Z., Powis, Stephen H., Fernando, Ray, Mon, Wint Y., Wheeler, David C., Moorhead, John F., Varghese, Zac

    Published in Kidney international (01-03-2005)
    “…EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-γ–dependent mechanism. Recent studies have shown that fish oil,…”
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    Renal vasoconstriction induced by oxidized LDL is inhibited by scavengers of reactive oxygen species and L-arginine by Rahman, M M, Varghese, Z, Fuller, B J, Moorhead, J F

    Published in Clinical nephrology (01-02-1999)
    “…Low density lipoprotein (LDL) may be involved in the pathogenesis of glomerulosclerosis and progressive renal dysfunction associated with atherosclerotic renal…”
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    Lipoprotein(a) in patients with proteinuria by Thomas, M E, Freestone, A, Varghese, Z, Persaud, J W, Moorhead, J F

    “…Lipoprotein(a) (Lp(a)) has recently been recognized to be a risk factor for coronary heart disease. Lp(a) median values in the absence of renal disease are…”
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    Association of primary sclerosing cholangitis with HLA-B8 by Chapman, R W, Varghese, Z, Gaul, R, Patel, G, Kokinon, N, Sherlock, S

    Published in Gut (01-01-1983)
    “…The frequency of HLA antigens was studied in 25 patients with primary sclerosing cholangitis and compared with a control group of 562 kidney donors. Fourteen…”
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