Search Results - "Varghese, Nevin J."
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Chronic skin inflammation accelerates macrophage cholesterol crystal formation and atherosclerosis
Published in JCI insight (11-01-2018)“…Inflammation is critical to atherogenesis. Psoriasis is a chronic inflammatory skin disease that accelerates atherosclerosis in humans and provides a…”
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Chronic Stress-Related Neural Activity Associates With Subclinical Cardiovascular Disease in Psoriasis: A Prospective Cohort Study
Published in JACC. Cardiovascular imaging (01-02-2020)“…This study hypothesized that there is an association between chronic stress (as indexed by resting amygdalar activity [AmygA]), hematopoietic system activity…”
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Cells of Myeloid Origin Partly Mediate the Association between Psoriasis Severity and Coronary Plaque
Published in Journal of investigative dermatology (01-04-2020)Get full text
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Association Between Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 and Coronary Artery Disease in Psoriasis
Published in JAMA dermatology (Chicago, Ill.) (01-02-2020)“…Psoriasis, a chronic inflammatory skin disease associated with accelerated noncalcified coronary burden (NCB) by coronary computed tomography angiography…”
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Basal Spontaneous Firing of Rabbit Sinoatrial Node Cells Is Regulated by Dual Activation of PDEs (Phosphodiesterases) 3 and 4
Published in Circulation. Arrhythmia and electrophysiology (01-06-2018)“…BACKGROUND:Spontaneous firing of sinoatrial node cells (SANCs) is regulated by cAMP-mediated, PKA (protein kinase A)-dependent (cAMP/PKA) local subsarcolemmal…”
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6
Chronic Stress-Related Neural Activity Associates With Subclinical Cardiovascular Disease in Psoriasis
Published in JACC. Cardiovascular imaging (01-02-2020)“…This study hypothesized that there is an association between chronic stress (as indexed by resting amygdalar activity [AmygA]), hematopoietic system activity…”
Get full text
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Basal Spontaneous Firing of Rabbit Sinoatrial Node Cells is Regulated by Dual Phosphodiesterase 3 and 4 Activation
Published in Circulation. Arrhythmia and electrophysiology (01-06-2018)Get full text
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Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis
Published in JACC. Basic to translational science (01-02-2019)“…Visual Abstract…”
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Abstract 14905: Association of Neutrophils and Neutrophil Extracellular Traps With Aortic Vascular Inflammation in Psoriasis
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionCardiovascular disease (CVD) risk is increased in psoriasis, a chronic inflammatory disease that affects 2-3% of the population. Notably, psoriasis…”
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Abstract 12604: Low Density Granulocytes, Platelets and Non-Calcified Coronary Plaque Burden in Psoriasis
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionThe chronic inflammatory skin disease psoriasis affects 2-3% of the population and is associated with increased cardiovascular disease (CVD) risk…”
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Abstract 12596: Immunomodulatory Therapy Favorably Modifies Coronary Plaque Morphology in Psoriasis
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionEvidence suggests that inflammatory mediators are important in the pathogenesis of atherosclerosis and their inhibition not only reduces…”
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Abstract 12603: Increased Resting Amygdala Activity Relates to Increased Prevalence of High Risk Coronary Plaque in Psoriasis
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionIn individuals without chronic inflammatory conditions, chronic stress independently associates with cardiovascular disease (CVD) in part via a…”
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