Search Results - "Vargas‐Castillo, Ariana"
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Genistein Stimulation of White Adipose Tissue Thermogenesis Is Partially Dependent on GPR30 in Mice
Published in Molecular nutrition & food research (01-04-2022)“…Scope Genistein increases whole body energy expenditure by stimulating white adipose tissue (WAT) browning and thermogenesis. G‐Coupled receptor GPR30 can…”
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Antibiotic Treatment Reduces the Health Benefits of Soy Protein
Published in Molecular nutrition & food research (01-09-2020)“…Scope Soy protein is a high‐quality protein and its consumption has been associated with a reduction of serum cholesterol and triglycerides and an improvement…”
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Establishment of triple-negative breast cancer cells based on BMI: A novel model in the correlation between obesity and breast cancer
Published in Frontiers in oncology (14-12-2022)“…Obesity has been associated with an increased risk of biologically aggressive variants in breast cancer. Women with obesity often have tumors diagnosed at…”
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Understanding the Biology of Thermogenic Fat: Is Browning A New Approach to the Treatment of Obesity?
Published in Archives of medical research (01-07-2017)“…Obesity is characterized by an excess of white adipose tissue (WAT). Recent evidence has demonstrated that WAT can change its phenotype to a brown-like adipose…”
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Genistein‐mediated thermogenesis and white‐to‐beige adipocyte differentiation involve transcriptional activation of cAMP response elements in the Ucp1 promoter
Published in The FASEB journal (01-08-2023)“…Genistein is an isoflavone present in soybeans and is considered a bioactive compound due to its widely reported biological activity. We have previously shown…”
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Pharmacological inhibition of tumor anabolism and host catabolism as a cancer therapy
Published in Scientific reports (04-03-2021)“…The malignant energetic demands are satisfied through glycolysis, glutaminolysis and de novo synthesis of fatty acids, while the host curses with a state of…”
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Genistein stimulates insulin sensitivity through gut microbiota reshaping and skeletal muscle AMPK activation in obese subjects
Published in BMJ open diabetes research & care (01-03-2020)“…ObjectiveObesity is associated with metabolic abnormalities, including insulin resistance and dyslipidemias. Previous studies demonstrated that genistein…”
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Editorial: Precision treatments for patients with obesity
Published in Frontiers in medicine (29-05-2024)Get full text
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Dietary bioactive compounds as modulators of mitochondrial function
Published in The Journal of nutritional biochemistry (01-10-2021)“…•Respirometry analysis allows the evaluation of mitochondrial function in real time.•Several food bioactives improve health via modulation of mitochondrial…”
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Genistein increases the thermogenic program of subcutaneous WAT and increases energy expenditure in mice
Published in The Journal of nutritional biochemistry (01-06-2019)“…White adipose tissue (WAT) can differentiate into beige adipose tissue by the browning process. Some polyphenols, including isoflavones, particularly…”
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Development of a functional beige fat cell line uncovers independent subclasses of cells expressing UCP1 and the futile creatine cycle
Published in Cell metabolism (03-09-2024)“…Although uncoupling protein 1 (UCP1) is established as a major contributor to adipose thermogenesis, recent data have illustrated an important role for…”
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Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes
Published in Cell metabolism (03-09-2024)“…Adipose tissue can recruit catabolic adipocytes that utilize chemical energy to dissipate heat. This process occurs either by uncoupled respiration through…”
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Angiotensin-(1-7) induces beige fat thermogenesis through the Mas receptor
Published in Metabolism, clinical and experimental (01-02-2020)“…Angiotensin-(1-7) [Ang-(1-7)], a component of the renin angiotensin system, is a vasodilator that exerts its effects primarily through the Mas receptor. The…”
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PPARα/RXRα downregulates amino acid catabolism in the liver via interaction with HNF4α promoting its proteasomal degradation
Published in Metabolism, clinical and experimental (01-03-2021)“…The preservation of body proteins is essential to guarantee their functions in organisms. Therefore, the utilization of amino acids as energy substrates is…”
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Inhibition of Angiotensin Converting Enzyme Induces Beige Adipocytes through Angiotensin‐(1–7) in 3T1‐L1 Adipocytes and Obese Mice
Published in The FASEB journal (01-04-2016)“…Abstract only The renin angiotensin system (RAS) has recently been recognized as an important factor in the regulation of energy balance. Adipocytes express…”
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Hipótesis sobre las conexiones entre COVID-19 severo en niños y nutrición: una revisión narrativa
Published in Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral (10-06-2021)“…Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). Compared with adults, children with SARS-CoV-2…”
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Hypothesis regarding the connections between severe COVID-19 in children and nutrition: a narrative review
Published in Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral (2021)“…Abstract Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). Compared with adults, children with…”
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AMPK Phosphorylation Effect of Genistein Is Independent of GPR30
Published in Current developments in nutrition (01-06-2020)“…Genistein promotes fatty acid oxidation, improves glucose tolerance and increases energy expenditure. These effects are associated with AMPK phosphorylation in…”
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