Search Results - "Vargas, Maxemiliano V."

Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors by Vargas, Maxemiliano V, Dunlap, Lee E, Dong, Chunyang, Carter, Samuel J, Tombari, Robert J, Jami, Shekib A, Cameron, Lindsay P, Patel, Seona D, Hennessey, Joseph J, Saeger, Hannah N, McCorvy, John D, Gray, John A, Tian, Lin, Olson, David E

“…Decreased dendritic spine density in the cortex is a hallmark of several neuropsychiatric diseases, and the ability to promote cortical neuron growth has been…”
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Psychedelics and Other Psychoplastogens for Treating Mental Illness by Vargas, Maxemiliano V, Meyer, Retsina, Avanes, Arabo A, Rus, Mark, Olson, David E

“…Psychedelics have inspired new hope for treating brain disorders, as they seem to be unlike any treatments currently available. Not only do they produce…”
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The Therapeutic Landscape of Rheumatoid Arthritis: Current State and Future Directions by Shams, Shahin, Martinez, Joseph M, Dawson, John R D, Flores, Juan, Gabriel, Marina, Garcia, Gustavo, Guevara, Amanda, Murray, Kaitlin, Pacifici, Noah, Vargas, Maxemiliano V, Voelker, Taylor, Hell, Johannes W, Ashouri, Judith F

“…Rheumatoid arthritis (RA) is a debilitating autoimmune disease with grave physical, emotional and socioeconomic consequences. Despite advances in targeted…”
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Psychedelic-inspired drug discovery using an engineered biosensor by Dong, Chunyang, Ly, Calvin, Dunlap, Lee E., Vargas, Maxemiliano V., Sun, Junqing, Hwang, In-Wook, Azinfar, Arya, Oh, Won Chan, Wetsel, William C., Olson, David E., Tian, Lin

“…Ligands can induce G protein-coupled receptors (GPCRs) to adopt a myriad of conformations, many of which play critical roles in determining the activation of…”
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A non-hallucinogenic psychedelic analogue with therapeutic potential by Cameron, Lindsay P., Tombari, Robert J., Lu, Ju, Pell, Alexander J., Hurley, Zefan Q., Ehinger, Yann, Vargas, Maxemiliano V., McCarroll, Matthew N., Taylor, Jack C., Myers-Turnbull, Douglas, Liu, Taohui, Yaghoobi, Bianca, Laskowski, Lauren J., Anderson, Emilie I., Zhang, Guoliang, Viswanathan, Jayashri, Brown, Brandon M., Tjia, Michelle, Dunlap, Lee E., Rabow, Zachary T., Fiehn, Oliver, Wulff, Heike, McCorvy, John D., Lein, Pamela J., Kokel, David, Ron, Dorit, Peters, Jamie, Zuo, Yi, Olson, David E.

“…The psychedelic alkaloid ibogaine has anti-addictive properties in both humans and animals 1 . Unlike most medications for the treatment of substance use…”
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Disentangling the acute subjective effects of classic psychedelics from their enduring therapeutic properties by Atiq, Mazen A, Baker, Matthew R, Voort, Jennifer L Vande, Vargas, Maxemiliano V, Choi, Doo-Sup

“…Recent research with classic psychedelics suggests significant therapeutic potential, particularly for neuropsychiatric disorders. A mediating influence behind…”
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5‑HT2ARs Mediate Therapeutic Behavioral Effects of Psychedelic Tryptamines by Cameron, Lindsay P., Patel, Seona D., Vargas, Maxemiliano V., Barragan, Eden V., Saeger, Hannah N., Warren, Hunter T., Chow, Winston L., Gray, John A., Olson, David E.

“…Psychedelic compounds have displayed antidepressant potential in both humans and rodents. Despite their promise, psychedelics can induce undesired effects that…”
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Transient Stimulation with Psychoplastogens Is Sufficient to Initiate Neuronal Growth by Ly, Calvin, Greb, Alexandra C, Vargas, Maxemiliano V, Duim, Whitney C, Grodzki, Ana Cristina G, Lein, Pamela J, Olson, David E

“…Cortical neuron atrophy is a hallmark of depression and includes neurite retraction, dendritic spine loss, and decreased synaptic density. Psychoplastogens,…”
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Bryostatin 1 Promotes Synaptogenesis and Reduces Dendritic Spine Density in Cortical Cultures through a PKC-Dependent Mechanism by Ly, Calvin, Shimizu, Akira J, Vargas, Maxemiliano V, Duim, Whitney C, Wender, Paul A, Olson, David E

“…The marine natural product bryostatin 1 has demonstrated procognitive and antidepressant effects in animals and has been entered into human clinical trials for…”
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