Search Results - "Vargas, M H"

Extracellular DNA traps in bronchoalveolar fluid from a murine eosinophilic pulmonary response by Cunha, A. A., Porto, B. N., Nuñez, N. K., Souza, R. G., Vargas, M. H. M., Silveira, J. S., Souza, T. T. R., Jaeger, N., Pitrez, P. M.

“…Asthma is associated with a loss of the structural integrity of airway epithelium and dysfunction of the physical barrier, which protects airways from external…”
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Detection of QTc interval prolongation using jacket telemetry in conscious non‐human primates: comparison with implanted telemetry by Derakhchan, K, Chui, R W, Stevens, D, Gu, W, Vargas, H M

“…Background and Purpose During repeat‐dose toxicity studies, ECGs are collected from chemically or physically‐restrained animals over a short timeframe. This is…”
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Inhibition of extracellular nucleotides hydrolysis intensifies the allergic bronchospasm. A novel protective role of ectonucleotidases by Chávez, J., Vargas, M. H., Rebollar‐Ayala, D. C., Díaz‐Hernández, V., Cruz‐Valderrama, J. E., Flores‐Soto, E., Flores‐García, M., Jiménez‐Vargas, N. N., Barajas‐López, C., Montaño, L. M.

“…Background Nucleotides released to the extracellular space stimulate purinergic receptors, and their effects are modulated by ectonucleotidases. The role of…”
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Role of 5-HT2A, 5-HT4 and 5-HT7 receptors in the antigen-induced airway hyperresponsiveness in guinea-pigs by Segura, P., Vargas, M. H., Córdoba-Rodríguez, G., Chávez, J., Arreola, J. L., Campos-Bedolla, P., Ruiz, V., García-Hernández, L. M., Méndez, C., Montaño, L. M.

“…Summary Background A possible role of 5‐hydroxytryptamine (5‐HT) in the origin of antigen‐induced airway hyperresponsiveness (AI‐AHR) has been scarcely…”
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Atypical radiological images of pulmonary tuberculosis in 192 diabetic patients: a comparative study by Pérez-Guzman, C, Torres-Cruz, A, Villarreal-Velarde, H, Salazar-Lezama, M A, Vargas, M H

“…SETTING: Comparative studies of pulmonary tuberculosis images in diabetics have yielded conflicting results.OBJECTIVE: To assess radiological images of…”
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Does aging modify pulmonary tuberculosis?: A meta-analytical review by Pérez-Guzmán, C, Vargas, M H, Torres-Cruz, A, Villarreal-Velarde, H

“…To evaluate the differences in the clinical, radiologic, and laboratory features of pulmonary tuberculosis (TB) in older patients, as compared to younger…”
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Reevaluating safety pharmacology respiratory studies within the ICH S7A core battery: A multi-company evaluation of preclinical utility and clinical translation by Friedrichs, G.S., Abernathy, M.M., Ackley, D., Clark, M., DaSilva, J.K., Foley, C.M., Greiter-Wilke, A., Henderson, K.A, Kremer, J.J., Morimoto, B.H., Paglialunga, S., Pugsley, M.K., Regan, C.P., Rossman, E.I., Segretti, J.A., Traebert, M., Vargas, H.M., Wisialowski, T.A.

“…Optimization of ICH safety guideline studies for inclusion into regulatory submissions is critical for resource conservation, animal use reduction, and…”
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Progressive age-related changes in pulmonary tuberculosis images and the effect of diabetes by PEREZ-GUZMAN, Carlos, TORRES-CRUZ, Alfredo, VILLARREAL-VELARDE, Hector, VARGAS, Mario H

“…Atypical radiologic images of pulmonary tuberculosis are common in elderly and in diabetic patients. To investigate the relationship of chest radiographic…”
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Guidelines for diagnosing and treating pulmonary infiltrates in children with acute leukaemia: impact of timely decisions by Furuya, MEY, González-Martínez, F, Vargas, MH, Miranda-Novales, MG, Bernáldez-Ríos, R, Zúñiga-Vázquez, G

“…Aim: Children with leukaemia are at increased risk of pulmonary complications, often with unspecific clinical data, delayed diagnosis and a high mortality…”
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Effect of altitude on the frequency of pulmonary tuberculosis by VARGAS, M. H, FURUYA, M. E. Y, PEREZ-GUZMAN, C

“…SETTING: Pulmonary tuberculosis (PTB) incidence greatly varies around the world, a phenomenon usually attributed to socio-economic factors or health service…”
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Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine by Bores, G M, Huger, F P, Petko, W, Mutlib, A E, Camacho, F, Rush, D K, Selk, D E, Wolf, V, Kosley, Jr, R W, Davis, L, Vargas, H M

“…Acetylcholinesterase (AChE) inhibitors from several chemical classes have been tested for the symptomatic treatment of Alzheimer's disease; however, the…”
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Input respiratory impedance in mice: comparison between the flow-based and the wavetube method to perform the forced oscillation technique by Mori, V, Oliveira, M A, Vargas, M H M, da Cunha, A A, de Souza, R G, Pitrez, P M, Moriya, H T

“…Objective and approach: In this study, we estimated the constant phase model (CPM) parameters from the respiratory impedance of male BALB/c mice by performing…”
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Results of a 12-month regimen for drug-resistant pulmonary tuberculosis by Pérez-Guzmán, Vargas M., Martínez-Rossier L., Torres-Cruz, Villarreal-Velarde

“…SETTING: Several therapeutic regimens for drug-resistant tuberculosis have been suggested, most of them with a total duration of 18-24 months.OBJECTIVE: To…”
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Immunohistochemical Expression of the Pluripotency Factor OCT4 in Canine Mast Cell Tumours by Vargas, T.H.M., Pulz, L.H., Barra, C.N., Kleeb, S.R., Xavier, J.G., Catão-Dias, J.L., Fukumasu, H., Nishiya, A.T., Strefezzi, R.F.

“…Cancer stem cells (CSCs) are related to malignancy and resistance to chemotherapy in several tumours. OCT4 is a ‘pluripotency factor’ that is expressed by…”
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An overview of the safety pharmacology society strategic plan by Pugsley, M.K., Authier, S., Koerner, J.E., Redfern, W.S., Markgraf, C.G., Brabham, T., Correll, K., Soloviev, M.V., Botchway, A., Engwall, M., Traebert, M., Valentin, J.-P., Mow, T.J., Greiter-Wilke, A., Leishman, D.J., Vargas, H.M.

“…Safety Pharmacology studies are conducted to characterize the confidence by which biologically active new chemical entities (NCE) may be anticipated as safe…”
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Decreased expression of ectonucleotidase E‐NPP1 in leukocytes from subjects with severe asthma exacerbation by Montaño, L. M., Vargas, M. H., Díaz‐Hernández, V., De Ita, M., Kazakova, R., Barajas‐López, C.

“…Several studies suggest that ATP and related nucleotides play a role in the pathophysiology of asthma. However, the functionality of ectonucleotidases in this…”
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Phenyl-substituted analogs of oxotremorine as muscarinic antagonists by Nilsson, Bjoern M, Vargas, Hugo M, Ringdahl, Bjoern, Hacksell, Uli

“…A series of phenyl-substituted analogues of the muscarinic agent oxotremorine (1) have been prepared. The new compounds (3b-11b and 9c) were assayed for…”
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Diabetes modifies the male:female ratio in pulmonary tuberculosis by PEREZ-GUZMAN, C, VARGAS, M. H, TORRES-CRUZ, A, PEREZ-PADILLA, J. R, FURUYA, M. E. Y, VILLARREAL-VELARDE, H

“…SETTING: Socio-cultural factors have been invoked to explain the male predominance among patients with pulmonary tuberculosis, but there is no conclusive…”
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5-HT Receptor Antagonism Attenuates the Ischemia-Reperfusion Injury After Rabbit Lung Preservation by Arreola-Ramírez, J.L, Alquicira-Mireles, J, Morales-Hernández, P.E, Vargas, M.H, Villalba-Caloca, J, Segura-Medina, P

“…Abstract The success of lung transplantation is threatened by the appearance of ischemia-reperfusion injury, which is characterized by increased vascular…”
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Bacterial extract (OM-85) with human-equivalent doses does not inhibit the development of asthma in a murine model by Rodrigues, A, Gualdi, L P, de Souza, R G, Vargas, M H M, Nuñez, N K, da Cunha, A A, Jones, M H, Pinto, L A, Stein, R T, Pitrez, P M

“…OM-85 is an immunostimulant bacterial lysate, which has been proven effective in reducing the number of lower airways infections. We investigated the efficacy…”
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