Search Results - "Vargas, Diana Y."

Single-Molecule Imaging of Transcriptionally Coupled and Uncoupled Splicing by Vargas, Diana Y., Shah, Khyati, Batish, Mona, Levandoski, Michael, Sinha, Sourav, Marras, Salvatore A.E., Schedl, Paul, Tyagi, Sanjay

“…Introns are removed from pre-mRNAs during transcription while the pre-mRNA is still tethered to the gene locus via RNA polymerase. However, during alternative…”
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Stochastic mRNA synthesis in mammalian cells by Raj, Arjun, Peskin, Charles S, Tranchina, Daniel, Vargas, Diana Y, Tyagi, Sanjay

“…Individual cells in genetically homogeneous populations have been found to express different numbers of molecules of specific proteins. We investigated the…”
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Multiplex Real-Time PCR Assays that Measure the Abundance of Extremely Rare Mutations Associated with Cancer by Vargas, Diana Y, Kramer, Fred Russell, Tyagi, Sanjay, Marras, Salvatore A E

“…We describe the use of "SuperSelective" primers that enable the detection and quantitation of somatic mutations whose presence relates to cancer diagnosis,…”
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Mechanism of mRNA Transport in the Nucleus by Diana Y. Vargas, Arjun Raj, Salvatore A. E. Marras, Kramer, Fred Russell, Tyagi, Sanjay

“…The mechanism of transport of mRNA-protein (mRNP) complexes from transcription sites to nuclear pores has been the subject of many studies. Using molecular…”
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Suppression of Wild-Type Amplification by Selectivity Enhancing Agents in PCR Assays that Utilize SuperSelective Primers for the Detection of Rare Somatic Mutations by Vargas, Diana Y., Marras, Salvatore A.E., Tyagi, Sanjay, Kramer, Fred R.

“…In PCR assays designed to detect rare somatic mutations, SuperSelective primers, by virtue of their short 3′-foot sequences, selectively initiate synthesis on…”
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Multiplex SuperSelective PCR Assays for the Detection and Quantitation of Rare Somatic Mutations in Liquid Biopsies by Vargas, Diana Y., Tyagi, Sanjay, Marras, Salvatore A.E., Moerzinger, Patricia, Abin-Carriquiry, Juan A., Cuello, Mauricio, Rodriguez, Clara, Martinez, Andrés, Makhnin, Alex, Farina, Andrea, Patel, Chintan, Chuang, Tuan L., Li, Bob T., Kramer, Fred R.

“…SuperSelective primers, by virtue of their unique design, enable the simultaneous identification and quantitation of inherited reference genes and rare somatic…”
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tRNA-linked molecular beacons for imaging mRNAs in the cytoplasm of living cells by Mhlanga, Musa M., Vargas, Diana Y., Fung, Cindy W., Kramer, Fred Russell, Tyagi, Sanjay

“…When oligonucleotide probes are microinjected into cells to image the distribution of RNAs, they are rapidly sequestered into the nucleus. As a result, it is…”
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