Search Results - "Varga, Renée"

Accumulation of Mutant Lamin A Causes Progressive Changes in Nuclear Architecture in Hutchinson-Gilford Progeria Syndrome by Goldman, Robert D., Shumaker, Dale K., Erdos, Michael R., Eriksson, Maria, Goldman, Anne E., Gordon, Leslie B., Gruenbaum, Yosef, Khuon, Satya, Mendez, Melissa, Varga, Renée, Collins, Francis S.

“…Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder, commonly caused by a point mutation in the lamin A gene that results in a protein…”
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Inhibiting Farnesylation of Progerin Prevents the Characteristic Nuclear Blebbing of Hutchinson-Gilford Progeria Syndrome by Capell, Brian C., Erdos, Michael R., Madigan, James P., Fiordalisi, James J., Varga, Renee, Conneely, Karen N., Gordon, Leslie B., Der, Channing J., Cox, Adrienne D., Collins, Francis S.

“…Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder that is characterized by dramatic premature aging and accelerated cardiovascular…”
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Progressive Vascular Smooth Muscle Cell Defects in a Mouse Model of Hutchinson-Gilford Progeria Syndrome by Varga, Renee, Eriksson, Maria, Erdos, Michael R., Olive, Michelle, Harten, Ingrid, Kolodgie, Frank, Capell, Brian C., Cheng, Jun, Faddah, Dina, Perkins, Stacie, Avallone, Hedwig, San, Hong, Qu, Xuan, Ganesh, Santhi, Gordon, Leslie B., Virmani, Renu, Wight, Thomas N., Nabel, Elizabeth G., Collins, Francis S.

“…Children with Hutchinson-Gilford progeria syndrome (HGPS) suffer from dramatic acceleration of some symptoms associated with normal aging, most notably…”
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The calcium-binding aspartate/glutamate carriers, citrin and aralar1, are new substrates for the DDP1/TIMM8a–TIMM13 complex by Roesch, Karin, Hynds, Peter J., Varga, Renee, Tranebjaerg, Lisbeth, Koehler, Carla M.

“…The biogenesis of the mitochondrial inner membrane is dependent on two distinct 70 kDa protein complexes. TIMM8a partners with TIMM13 in the mitochondrial…”
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Farnesylated proteins: how do they get to where they need to go, and how does location regulate their ability to control proliferation, death, transformation and aging? by Cox, Adrienne D., Madigan, James P., Fiordalisi, James J., Der, Channing J., Berzat, Anastacia C., Philips, Mark R., Bivona, Trever, Ahearn, Ian, Quatela, Steven, Capell, Brian C., Erdos, Michael R., Gordon, Leslie B., Varga, Renee, Collins, Francis S.

“…Ras and Rho family small GTPases require post‐translational modification by isoprenoid lipids in order to localize correctly within the cell and to transmit…”
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Progressive vascular smooth muscle defects in a mouse model of Hutchinson–Gilford Progeria Syndrome by Vermani, Renu, Olive, Michelle, Wright, Tom, Collins, Francis, Nabel, Elizabeth, Varga, Renee, Eriksson, Maria, San, Hong, Erdos, Mike, Capell, Brian, Ganesh, Santhi, Kolodgie, Franck

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