Search Results - "Varenbut, Michael"
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The association between age of onset of opioid use and comorbidity among opioid dependent patients receiving methadone maintenance therapy
Published in Addiction science & clinical practice (28-03-2017)“…Opioid use disorder (OUD) affects approximately 21.9 million people worldwide. This study aims to determine the association between age of onset of opioid use…”
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Association between cannabis use and methadone maintenance treatment outcomes: an investigation into sex differences
Published in Biology of sex differences (30-03-2017)“…Cannabis will soon become legalized in Canada, and it is currently unclear how this will impact public health. Methadone maintenance treatment (MMT) is the…”
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A Prospective Study to Investigate Predictors of Relapse among Patients with Opioid Use Disorder Treated with Methadone
Published in Substance abuse : research and treatment (01-01-2016)“…Introduction Concomitant opioid abuse is a serious problem among patients receiving methadone maintenance treatment (MMT) for opioid use disorder. This is an…”
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Impact of Chronic Pain on Treatment Prognosis for Patients with Opioid Use Disorder: A Systematic Review and Meta-analysis
Published in Substance Abuse: Research and Treatment (01-01-2015)“…Background While a number of pharmacological interventions exist for the treatment of opioid use disorder, evidence evaluating the effect of pain on substance…”
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Sex differences in outcomes of methadone maintenance treatment for opioid use disorder: a systematic review and meta-analysis
Published in CMAJ open (01-07-2015)“…Background Opioid use disorder is a serious international concern with limited treatment success. Men and women differ in their susceptibility to opioid use…”
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The effectiveness of telemedicine-delivered opioid agonist therapy in a supervised clinical setting
Published in Drug and alcohol dependence (01-07-2017)“…Highlights • Telemedicine may be an effective treatment modality to deliver opioid agonist therapy (OAT). • Telemedicine patients are retained in OAT as…”
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Tampering by office-based methadone maintenance patients with methadone take home privileges: a pilot study
Published in Harm reduction journal (30-10-2007)“…Methadone Maintenance Treatment (MMT) is among the most widely studied treatments for opiate dependence with proven benefits for patients and society. When…”
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Testosterone suppression in opioid users: A systematic review and meta-analysis
Published in Drug and alcohol dependence (01-04-2015)“…Highlights • Testosterone is suppressed by nearly 50% in opioid-using men. • This suppression is not specific to methadone but to all opioids in general,…”
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The effectiveness of telemedicine-delivered opioid agonist therapy in a supervised clinical settingO
Published in Drug and alcohol dependence (01-07-2017)“…Opioid use disorder has been declared a public health crisis across North America and opioid agonist therapy (OAT) is the standard of care for these patients…”
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Sex differences in substance use, health, and social functioning among opioid users receiving methadone treatment: a multicenter cohort study
Published in Biology of sex differences (10-11-2015)“…Despite the growing numbers of men and women with opioid use disorder in Canada, sex-specific issues in treatment have not been re-examined in the current…”
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Opioid substitution and antagonist therapy trials exclude the common addiction patient: a systematic review and analysis of eligibility criteria
Published in Current controlled trials in cardiovascular medicine (21-10-2015)“…Eligibility criteria that result in the exclusion of a substantial number of patients from randomized trials jeopardize the generalizability of treatment…”
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Methadone induces testosterone suppression in patients with opioid addiction
Published in Scientific reports (26-08-2014)“…Sex hormones may have a role in the pathophysiology of substance use disorders, as demonstrated by the association between testosterone and addictive behaviour…”
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Evaluating the effectiveness of telehealth-delivered opioid agonist therapy across Ontario, Canada
Published in Drug and alcohol dependence (01-11-2015)Get full text
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Usefulness of the Brief Pain Inventory in Patients with Opioid Addiction Receiving Methadone Maintenance Treatment
Published in Pain physician (01-01-2016)“…Chronic pain is implicated as a risk factor for illicit opioid use among patients with opioid addiction treated with methadone. However, there exists…”
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The effectiveness of opioid substitution treatments for patients with opioid dependence: a systematic review and multiple treatment comparison protocol
Published in Systematic reviews (19-09-2014)“…Opioids are psychoactive analgesic drugs prescribed for pain relief and palliative care. Due to their addictive potential, effort and vigilance in controlling…”
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The Cost of Providing Methadone Maintenance Treatment in Ontario, Canada
Published in The American journal of drug and alcohol abuse (01-11-2012)“…Objectives: To estimate the cost of providing methadone maintenance treatment in Ontario, Canada, from the perspective of the public payer. Methods: We…”
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Contribution of BDNF and DRD2 genetic polymorphisms to continued opioid use in patients receiving methadone treatment for opioid use disorder: an observational study
Published in Addiction science & clinical practice (06-10-2015)“…The heritability of opioid use disorder has been widely investigated; however, the influence of specific genes on methadone treatment outcomes is not well…”
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Genetic influence on methadone treatment outcomes in patients undergoing methadone maintenance treatment for opioid addiction: a pilot study
Published in Neuropsychiatric disease and treatment (01-01-2014)“…Treatment of opioid addiction with methadone is effective; however, it is known to produce interindividual variability. This may be influenced in part by…”
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The impact of chronic pain on opioid addiction treatment: a systematic review protocol
Published in Systematic reviews (16-04-2015)“…The consequences of opioid relapse among patients being treated with opioid substitution treatment (OST) are serious and can result in abnormal cardiovascular…”
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The Value of Clinical Case Management in a Methadone Maintenance Treatment Program
Published in The American journal of drug and alcohol abuse (01-01-2012)“…Background/Objective: This study sought to determine whether case management was positively associated with improved outcomes and treatment compliance in those…”
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