Search Results - "Varanasi, Kanthikiran VS"
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Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study
Published in Journal of mass spectrometry. (01-12-2012)“…A sensitive and reliable high‐performance liquid chromatography–mass spectrometry (LC–MS/MS) was developed and validated for simultaneous quantification…”
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Journal Article -
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Abstract 4489: Preclinical profile of novel, potent, and selective PI3K delta inhibitors
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract Background: Phosphoinositide-3 kinase (PI3K) belongs to a class of intracellular lipid kinases that phosphorylate the 3 position hydroxyl group of the…”
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Journal Article -
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Abstract C212: Pharmacological and pharmacokinetc characterization of RP1040, a novel and potent c-Met tyrosine kinase inhibitor
Published in Molecular cancer therapeutics (10-12-2009)“…Abstract Background: Receptor tyrosine kinases (RTK) represent a class of high affinity cell surface receptors that play a critical role in the development and…”
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Journal Article