Search Results - "Varagunam, M"

Changes in volume, clinical practice and outcome after reorganisation of oesophago-gastric cancer care in England: A longitudinal observational study by Varagunam, M., Hardwick, R., Riley, S., Chadwick, G., Cromwell, D.A., Groene, O.

“…The centralisation of oesophago-gastric (O-G) cancer services in England was recommended in 2001, partly because of evidence for a volume-outcome effect for…”
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Brachytherapy in the Palliation of Oesophageal Cancer: Effective but Impractical? by Sinha, S., Varagunam, M., Park, M.H., Maynard, N.D., Trudgill, N., Crosby, T., Cromwell, D.A.

“…Dysphagia in people with advanced oesophageal cancer can be treated by oesophageal stents, external beam radiotherapy (EBRT) and intraluminal brachytherapy…”
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Population-based cohort study of the management and survival of patients with early-stage oesophageal adenocarcinoma in England by Chadwick, G., Riley, S., Hardwick, R. H., Crosby, T., Hoare, J., Hanna, G., Greenaway, K., Varagunam, M., Cromwell, D. A., Groene, O.

“…Background Until recently, oesophagectomy was the treatment of choice for early oesophageal cancer. Endoscopic treatment has been introduced relatively…”
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Influence of surgical rate on patients' reported clinical need and outcomes in English NHS by Black, N., Varagunam, M., Hutchings, A.

“…Background To determine if higher rates of surgery are associated with lower levels of need (patients' pre-operative reports of their symptoms, functional…”
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Pretransplant Donor-Specific Antibodies in Cytotoxic Negative Crossmatch Kidney Transplants : Are They Relevant? by WAGNER, Martin, ZOLLNER, Gernot, TRAUNER, Michael, GUPTA, Arun, IVESON, Victoria, VARAGUNAM, Mira, BODGER, Stephen, SINNOTT, Paul, THURAISINGHAM, Raj C

“…The corresponding antigens of alloantibodies identified in patients awaiting kidney transplantation are often listed as unacceptable for transplantation. The…”
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High glucose‐induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases by Allen, David A., Harwood, Steven M., Varagunam, Mira, Raftery, Martin J., Yaqoob, Muhammad M.

“…ABSTRACT Diabetic nephropathy is the leading cause of end‐stage renal disease in the Western world. Poor glycemic control contributes to the development of…”
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Anti‐idiotypic activity against anti‐myeloperoxidase antibodies in pooled human immunoglobulin by PALL, A. A., VARAGUNAM, M., ADU, D., SMITH, N., RICHARDS, N. T., TAYLOR, C. M., MICHAEL, J.

“…SUMMARY We investigated the ability of six different pooled human immunoglobulin (PHIG) preparations to inhibit the binding of anti‐myeloperoxidase (MPO)…”
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Creatinine reduction ratio: a useful marker to identify medium and high-risk renal transplants by Vilar, Enric, Varagunam, Mira, Yaqoob, Muhammad M, Raftery, Martin, Thuraisingham, Raj

“…Delayed graft function (DGF) has a major impact on long-term renal transplant survival. However, it is a diagnosis made retrospectively with little opportunity…”
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Little evidence for anti-endothelial cell antibodies in microscopic polyarteritis and Wegener's granulomatosis by Varagunam, M, Nwosu, Z, Adu, D, Garner, C, Taylor, C M, Michael, J, Thompson, R A

“…We studied sera from patients with vasculitis and controls for the presence of anti-endothelial cell antibodies (AECA) and correlated these with disease type,…”
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THE CREATININE REDUCTION RATIO BETWEEN DAYS ONE AND TWO (CRR2) IS AN EARLY INDEPENDENT PREDICTOR OF POOR LONG TERM RENAL GRAFT SURVIVAL: 1372 by Thuraisingham, R, VIllar, E, Varagunam, M, Yaqoob, M

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High Pre‐Transplant Soluble CD30 Levels are Predictive of the Grade of Rejection by Rajakariar, Ravindra, Jivanji, Naina, Varagunam, Mira, Rafiq, Mohammad, Gupta, Arun, Sheaff, Michael, Sinnott, Paul, Yaqoob, MM

“…In renal transplantation, serum soluble CD30 (sCD30) levels in graft recipients are associated with increased rejection and graft loss. We investigated whether…”
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Pooled human IGG (PHIG) inhibits the binding of anti-myeloperoxidase antibodies to myeloperoxidase by Pall, A A, Varagunam, M, Adu, D, Smith, N, Taylor, C M, Michael, J

“…This study demonstrates that pooled human immunoglobulin (PHIG) contains anti-idiotypes to anti-myeloperoxidase (MPO) antibodies and can inhibit the binding of…”
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Little evidence for anti-endothelial-cell antibodies in microscopic polyarteritis and Wegener's granulomatosis by Varagunam, M, Nwosu, A C, Adu, D, Garner, C, Taylor, C M, Michael, J, Thompson, R A

“…Sera from patients with a vasculitis and controls were investigated for the presence of anti-endothelial cell antibodies(AECA), anti- neutrophil cytoplasmic…”
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Endothelium, myeloperoxidase, anti-myeloperoxidase interaction in vasculitis by Varagunam, M, Adu, D, Taylor, C M, Michael, J, Richards, N, Neuberger, J, Thompson, R A

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Pretransplantation levels of C-reactive protein predict all-cause and cardiovascular mortality, but not graft outcome, in kidney transplant recipients by Varagunam, Mira, Finney, Hazel, Trevitt, Ray, Sharples, Edward, McCloskey, Daniel J., Sinnott, Paul J., Raftery, Martin J., Yaqoob, Muhammad M.

“…Background: Chronic inflammation, the common pathway that leads to cardiovascular disease and chronic allograft nephropathy after transplantation, is prevalent…”
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THE EFFECT OF PROINFLAMMATORY CYTOKINE GENE AND ANGIOTENSIN-CONVERTING ENZYME POLYMORPHISMS ON ERYTHROPOIETIN REQUIREMENTS IN PATIENTS ON CONTINUOUS AMBULATORY PERITONEAL DIALYSIS by Sharples, Edward J, Varagunam, Mira, Sinnott, Paul J, McCloskey, Daniel J, Raftery, Martin J, Yaqoob, Mohammad M

“…Department of Renal Medicine and Transplantation, 1 Royal London and St Bartholomew's Hospital; Tissue Typing Laboratory, 2 Royal London Hospital, Whitechapel,…”
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Cytokines in haemolytic uraemic syndrome associated with verocytotoxin-producing Escherichia coli infection by Inward, C D, Varagunam, M, Adu, D, Milford, D V, Taylor, C M

“…The proinflammatory cytokines tumour necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, and IL-8 were measured in plasma and urine samples from 19 children…”
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Angiotensin-converting enzyme gene polymorphism and erythropoietin requirement by Varagunam, M, McCloskey, DJ, Sinnott, PJ, Raftery, MJ, Yaqoob, MM

“…Experimental Medicine and Nephrology, St. Bartholomews and the Royal London Medical School, London, United Kingdom. m.varagunam@qmul.ac.uk…”
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