Search Results - "Varadhachary, Gauri Rajani"
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Gender disparity in authorship of clinical trials leading to cancer drug approvals between 2008 and 2018: The glass ceiling of academic oncology
Published in Journal of clinical oncology (01-06-2022)“…11048 Background: Authorship, expressly premier positions (first, corresponding, or senior author), in peer reviewed journals is widely acknowledged as…”
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Value appraisal of FDA approved cancer drugs over the past decade
Published in Journal of clinical oncology (20-09-2019)“…Abstract only 115 Background: Value based drug pricing is emerging as an imperative health care precept in recognition of the ever-increasing drug costs,…”
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Value appraisal of FDA approved cancer drugs over the past decade
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e18385 Background: Value based drug pricing is emerging as an imperative health care precept in recognition of the ever-increasing drug costs,…”
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Adaptive Dose Escalation Trial of Stereotactic Body Radiation Therapy (SBRT) in combination with GC4419 in pancreatic cancer
Published in Journal of clinical oncology (20-05-2019)“…Abstract only TPS4164 Background: Local progression causes up to 30% of deaths from pancreatic cancer (PC) and is also a significant source of morbidity…”
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A retrospective analysis of antibiotics usage and effect on overall survival and progressive free survival in patients with metastatic pancreatic cancer
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e15781 Background: Recent studies have shown that the pancreatic ductal adenocarcinoma (PDAC)-associated gut microbiome can play a major in…”
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Female representation in clinical trials leading to FDA cancer drug approvals for gastrointestinal (GI) cancers between 2008 to 2018
Published in Journal of clinical oncology (01-02-2020)“…Abstract only 809 Background: Proportionate representation of women in health research is an area for improvement. This study aims to assess the representation…”
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Comprehensive genomic profiling of malignant peritoneal mesothelioma (MPeM) reveals key genomic alterations (GAs) distinct from malignant pleural mesothelioma (MPM)
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 8557 Background: MPeM is a rare and aggressive cancer with very limited treatment options. Lack of dedicated research has impeded improvements in…”
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The effect of antibiotic use on survival of patients with resected pancreatic ductal adenocarcinoma
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e15773 Background: Recent studies showed that gut microbial dysbiosis can affect carcinogenesis and tumor responses to therapies. Antibiotics,…”
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FOLFIRINOX in pancreatic cancer patients age 75 years or older
Published in Journal of clinical oncology (01-02-2019)“…Abstract only 362 Background: Although FOLFIRINOX (5-Fluorouracil + leucovorin + irinotecan + oxaliplatin) is now the standard of care for patients (pts) with…”
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A phase II trial of atezolizumab and bevacizumab in patients with relapsed/refractory and unresectable malignant peritoneal mesothelioma
Published in Journal of clinical oncology (20-05-2020)“…Abstract only 9013 Background: Malignant peritoneal mesothelioma (MPeM) is an orphan malignancy. No recommended/FDA approved therapies exist for salvage…”
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Prospective study for comprehensive genomic profiling (GP) in cancer of unknown primary (CUP): Feasibility, molecular landscape, and clinical utility in current era
Published in Journal of clinical oncology (01-02-2020)“…Abstract only 834 Background: CUP presents a unique niche and challenge for application of GP. Absence of a primary limits consensus regarding site-directed…”
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Adoptive transfer of tumor-infiltrating lymphocytes in patients with sarcomas, ovarian, and pancreatic cancers
Published in Journal of clinical oncology (20-05-2019)“…Abstract only TPS2650 Background: Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TIL) has a long history of efficacy in metastatic melanoma,…”
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Abstract CT220: A randomized multicenter phase Ib/II study to assess the safety and the immunological effect of chemoradiation therapy (CRT) in combination with Pembrolizumab (anti-PD1) to CRT alone in patients with resectable or borderline resectable pancreatic canc
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract Background: Immunotherapy has recently emerged as a promising modality in cancer treatment, but little is known about the application of this modality…”
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