Search Results - "Vaque, José Pedro"

Increased risk of MAFLD and Liver Fibrosis in Inflammatory Bowel Disease Independent of Classic Metabolic Risk Factors by Rodriguez-Duque, Juan Carlos, Calleja, José Luis, Iruzubieta, Paula, Hernández-Conde, Marta, Rivas-Rivas, Coral, Vera, María Isabel, Garcia, Maria Jose, Pascual, Marta, Castro, Beatriz, García-Blanco, Agustín, García-Nieto, Enrique, Olmo, Soraya Curiel-del, Cagigal, María Luisa, Lopez-Montejo, Lorena, Fernández-Lamas, Tatiana, Rasines, Laura, Fortea, José Ignacio, Vaque, José Pedro, Frias, Yza, Rivero, Montserrat, Arias-Loste, María Teresa, Crespo, Javier

“…There is conflicting evidence regarding the prevalence of and risk factors for metabolic-associated fatty liver disease (MAFLD) in patients with inflammatory…”
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Mycosis Fungoides and Sézary Syndrome: An Integrative Review of the Pathophysiology, Molecular Drivers, and Targeted Therapy by García-Díaz, Nuria, Piris, Miguel Ángel, Ortiz-Romero, Pablo Luis, Vaqué, José Pedro

“…Primary cutaneous T-cell lymphomas (CTCLs) constitute a heterogeneous group of diseases that affect the skin. Mycosis fungoides (MF) and Sézary syndrome (SS)…”
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Successful Direct Acting Antiviral Therapy in Chronic Hepatitis C Normalizes IFNγ and IL2 Production in T Cells Together with TLR8 Expression and Functionality in Peripheral Blood Mononuclear Cells by Arias-Loste, María Teresa, Cabezas, Joaquín, Llerena, Susana, Iruzubieta, Paula, San-Segundo, David, Merino, David, Cuadrado, Antonio, Vaqué, José Pedro, López-Hoyos, Marcos, Crespo, Javier

“…Chronic hepatitis C infection (HCV) activates a systemic cell-mediated immune response characterized by the production of IFNγ and an innate immune response…”
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Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics by Ruso-Julve, Fulgencio, Pombero, Ana, Pilar-Cuéllar, Fuencisla, García-Díaz, Nuria, Garcia-Lopez, Raquel, Juncal-Ruiz, María, Castro, Elena, Díaz, Álvaro, Vazquez-Bourgón, Javier, García-Blanco, Agustín, Garro-Martinez, Emilio, Pisonero, Helena, Estirado, Alicia, Ayesa-Arriola, Rosa, López-Giménez, Juan, Mayor, Federico, Valdizán, Elsa, Meana, Javier, Gonzalez-Maeso, Javier, Martínez, Salvador, Vaqué, José Pedro, Crespo-Facorro, Benedicto

“…A better understanding of the molecular mechanisms that participate in the development and clinical manifestations of schizophrenia can lead to improve our…”
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Ultrasensitive Electrochemical Immunosensor for Oral Cancer Biomarker IL-6 Using Carbon Nanotube Forest Electrodes and Multilabel Amplification by Malhotra, Ruchika, Patel, Vyomesh, Vaqué, Jose Pedro, Gutkind, J. Silvio, Rusling, James F

“…Squamous cell carcinomas of head and neck (HNSCC) are associated with immune, inflammatory, and angiogenic responses involving interleukin-6 (IL-6). This…”
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Combination of JAKi and HDACi Exerts Antiangiogenic Potential in Cutaneous T-Cell Lymphoma by Karagianni, Fani, Piperi, Christina, Valero-Diaz, Sara, Amato, Camilla, Vaque, Jose Pedro, Casar, Berta, Papadavid, Evangelia

“…Angiogenesis plays a pivotal role in the growth and metastasis of tumors, including the development and progression of cutaneous lymphomas. The chick embryo…”
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Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas by González-Vela, María del Carmen, Curiel-Olmo, Soraya, Derdak, Sophia, Beltran, Sergi, Santibañez, Miguel, Martínez, Nerea, Castillo-Trujillo, Alfredo, Gut, Martha, Sánchez-Pacheco, Roxana, Almaraz, Carmen, Cereceda, Laura, Llombart, Beatriz, Agraz-Doblas, Antonio, Revert-Arce, José, López Guerrero, José Antonio, Mollejo, Manuela, Marrón, Pablo Isidro, Ortiz-Romero, Pablo, Fernandez-Cuesta, Lynnette, Varela, Ignacio, Gut, Ivo, Cerroni, Lorenzo, Piris, Miguel Ángel, Vaqué, José Pedro

“…Merkel cell carcinoma (MCC) is a highly malignant neuroendocrine tumor of the skin whose molecular pathogenesis is not completely understood, despite the role…”
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PLCγ1/PKCθ Downstream Signaling Controls Cutaneous T-Cell Lymphoma Development and Progression by García-Díaz, Nuria, Casar, Berta, Alonso-Alonso, Ruth, Quevedo, Laura, Rodríguez, Marta, Ruso-Julve, Fulgencio, Esteve-Codina, Anna, Gut, Marta, Gru, Alejandro A., González-Vela, María Carmen, Gut, Ivo, Rodriguez-Peralto, José Luis, Varela, Ignacio, Ortiz-Romero, Pablo Luis, Piris, Miguel A., Vaqué, José Pedro

“…Developing mechanistic rationales can improve the clinical management of cutaneous T-cell lymphomas. There is considerable genetic and biological evidence of a…”
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NanoString analysis of mycosis fungoides reveals individual molecular identity by Alonso-Alonso, Ruth, Rodríguez, Marta, García-Díaz, Nuria, Tomás-Roca, Laura, Borregón, Jennifer, Cabezuelo-Rodríguez, Marta, Rebollo-González, Marcos, Gallego-Manzano, Luis, Cereceda, Laura, Rodriguez-Pinilla, Socorro María, Córdoba, Raúl, Fernando García, Juan, Torre-Castro, Juan, García-Álvarez, Carmen M, Del Mar Onteniente Gomis, María, Rivera-Díaz, Raquel, Rodriguez-Peralto, José Luis, Vaqué, José Pedro, Ortiz-Romero, Pablo Luis, Piris, Miguel Á

“…Gene profiling using a customized NanoString platform can be applied to routine mycosis fungoides (MF) samples, revealing their specific molecular features…”
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The presence of Merkel cell carcinoma polyomavirus is associated with a distinct phenotype in neoplastic Merkel cell carcinoma cells and their tissue microenvironment by Mendoza, María-Dolores, Santonja, Carlos, Gonzalez-Vela, Carmen, Concha, Angel, Iglesias Pena, Nicolás, Andrés-Esteban, Eva-Maria, Vaque, Jose Pedro, Cereceda, Laura, Pajares, Raquel, Kutzner, H, Requena, Luis, Piris, Miguel A

“…Aims Merkel cell carcinoma (MCC) is an aggressive primary neuroendocrine tumor of the skin, associated with Merkel cell polyomavirus (MCPyV) in 49-89% of…”
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Activity and safety of topical pimecrolimus in patients with early stage mycosis fungoides (PimTo-MF): a single-arm, multicentre, phase 2 trial by Ortiz-Romero, Pablo L, Maroñas Jiménez, Lidia, Muniesa, Cristina, Estrach, Teresa, Servitje, Octavio, Fernández-de-Misa, Ricardo, Gallardo, Fernando, Sanmartín, Onofre, Riveiro-Falkenbach, Erica, García-Díaz, Nuria, Vega, Rosa, Lora, David, Postigo, Concepción, Jiménez, Blanca, Sánchez-Beato, Margarita, Pedro Vaqué, José, Rodríguez Peralto, José Luis, de la Cámara, Agustín Gómez, de la Cruz, Javier, Piris Pinilla, Miguel Ángel

“…The calcineurin pathway is often activated in mycosis fungoides. We aimed to assess the activity and safety of topical pimecrolimus, a calcineurin inhibitor,…”
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Clinical and molecular characterization of steatotic liver disease in the setting of immune-mediated inflammatory diseases by García-Nieto, Enrique, Rodriguez-Duque, Juan Carlos, Rivas-Rivas, Coral, Iruzubieta, Paula, Garcia, María José, Rasines, Laura, Alvarez-Cancelo, Ana, García-Blanco, Agustín, Fortea, José Ignacio, Puente, Angela, Castro, Beatriz, Cagigal, Maria Luisa, Rueda-Gotor, Javier, Blanco, Ricardo, Rivero, Montserrat, Armesto, Susana, González-López, Marcos Antonio, Codina, Anna Esteve, Gut, Marta, Vaque, Jose Pedro, Crespo, Javier, Arias-Loste, María Teresa

“…Growing evidence suggests an increased prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) in the context of immune-mediated…”
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Depicting a network of PKCθ effectors and their roles in the biology of CTCL cells by Merino, Maria, Vaqué, José Pedro

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Bobel-24 and derivatives induce caspase-independent death in pancreatic cancer regardless of apoptotic resistance by Parreño, Matilde, Casanova, Isolda, Céspedes, María Virtudes, Vaqué, Jose Pedro, Pavón, Miguel Angel, Leon, Javier, Mangues, Ramon

“…The poor prognosis of pancreatic cancer and poor sensitivity to current therapeutics, associated with resistance to apoptosis, urge the search for new drugs…”
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Identification of tipifarnib sensitivity biomarkers in T-cell acute lymphoblastic leukemia and T-cell lymphoma by Alonso-Alonso, Ruth, Mondéjar, Rufino, Martínez, Nerea, García-Diaz, Nuria, Pérez, Cristina, Merino, David, Rodríguez, Marta, Esteve-Codina, Anna, Fuste, Berta, Gut, Marta, Burrows, Francis, Scholz, Catherine, Vaqué, Jose Pedro, Gualberto, Antonio, Piris, Miguel Ángel

“…Patients diagnosed with T-cell leukemias and T-cell lymphomas (TCLs) still have a poor prognosis and an inadequate response to current therapies, highlighting…”
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Molecular basis of targeted therapy in T/NK-cell lymphoma/leukemia: A comprehensive genomic and immunohistochemical analysis of a panel of 33 cell lines by Mondejar, Rufino, Pérez, Cristina, Onaindia, Arantza, Martinez, Nerea, González-Rincón, Julia, Pisonero, Helena, Vaqué, Jose Pedro, Cereceda, Laura, Santibañez, Miguel, Sánchez-Beato, Margarita, Piris, Miguel Angel

“…T and NK-cell lymphoma is a collection of aggressive disorders with unfavorable outcome, in which targeted treatments are still at a preliminary phase. To gain…”
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PLCγ1/PKCθ and its downstream effectors in cutaneous T-cell lymphoma development and progression by García-Diaz, Nuria, Casar, Berta, Alonso-Alonso, Ruth, Rodriguez, Marta, Ruso-Julve, Fulgencio, Esteve-Codina, Anna, Gru, Alejandro A, Gut, Marta, Gut, Ivo, Gonzalez-Vela, Carmen, Rodriguez-Peralto, José Luis, Varela, Ignacio, Ortiz-Romero, Pablo Luis, Piris, Miguel Ángel, Vaqué, José Pedro

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Applied diagnostics in liver cancer. Efficient combinations of sorafenib with targeted inhibitors blocking AKT/mTOR by Llerena, Susana, García-Díaz, Nuria, Curiel-Olmo, Soraya, Agraz-Doblas, Antonio, García-Blanco, Agustín, Pisonero, Helena, Varela, María, Santibáñez, Miguel, Almaraz, Carmen, Cereceda, Laura, Martínez, Nerea, Arias-Loste, María Teresa, Puente, Ángela, Martín-Ramos, Luis, de Lope, Carlos Rodríguez, Castillo-Suescun, Federico, Cagigas-Fernandez, Carmen, Isidro, Pablo, Lopez-López, Carlos, Lopez-Hoyos, Marcos, Llorca, Javier, Agüero, Jesús, Crespo-Facorro, Benedicto, Varela, Ignacio, Piris, Miguel Ángel, Crespo, Javier, Vaqué, José Pedro

“…Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related deaths worldwide. There is increasing interest in developing specific markers…”
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Mutational Status of Splenic Diffuse Red Pulp Small B-Cell Lymphoma Revealed By Whole Exome Sequencing by Martinez, Nerea, Almaraz, Carmen, Mollejo, Manuela, Campos-Martin, Yolanda, Derdak, Sophia, Cereceda, Laura, Traverse-Glehen, Alexandra, Verney, Aurelie, Baseggio, Lucile, Camacho, Fanny, Vaque, Jose Pedro, Beltran, Sergi, Gut, Ivo, Piris, Miguel Angel A.

“…Background: Splenic diffuse red pulp lymphoma (SDRPL) is a rare small B cell neoplasm provisionally included in a category of unclassifiable splenic B-cell…”
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Erratum: Individualized strategies to target specific mechanisms of disease in malignant melanoma patients displaying unique mutational signatures by Curiel-Olmo, Soraya, García-Castaño, Almudena, Vidal, Rebeca, Pisonero, Helena, Varela, Ignacio, León-Castillo, Alicia, Trillo, Eugenio, González-Vela, Carmen, García-Diaz, Nuria, Almaraz, Carmen, Moreno, Thaidy, Cereceda, Laura, Madureira, Rebeca, Martinez, Nerea, Ortiz-Romero, Pablo, Valdizán, Elsa, Piris, Miguel Angel, Vaqué, José Pedro

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