Search Results - "Vanzant, Erin"
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Human Myeloid-derived Suppressor Cells are Associated With Chronic Immune Suppression After Severe Sepsis/Septic Shock
Published in Annals of surgery (01-04-2017)“…OBJECTIVE:We hypothesized that after sepsis in humans, MDSCs will be persistently increased, functionally immunosuppressive, and associated with adverse…”
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Obesity and Associated Outcomes for Blunt vs Penetrating Mechanism in Trauma Laparotomy Patients
Published in The American surgeon (01-08-2024)“…Obesity in trauma patients is an established risk factor contributing to postoperative complications, but the relationship between body mass index (BMI) and…”
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Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma
Published in The journal of trauma and acute care surgery (01-01-2014)“…We recently proffered that a new syndrome persistent inflammation, immunosuppression, and catabolism syndrome (PICS) has replaced late multiple-organ failure…”
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Is there value in plasma cytokine measurements in patients with severe trauma and sepsis?
Published in Methods (San Diego, Calif.) (15-05-2013)“…•Some believe plasma cytokine levels can assess the inflammatory state of patients.•TNFα and IL-1β were initially considered good biomarkers in trauma and…”
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Chronic Critical Illness and PICS Nutritional Strategies
Published in Journal of clinical medicine (25-05-2021)“…The nutritional hallmark of chronic critical illness (CCI) after sepsis is persistent inflammation, immunosuppression, and catabolism syndrome (PICS), which…”
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Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock
Published in Critical care (London, England) (04-03-2015)“…We wished to characterize the relationship of advanced age to clinical outcomes and to transcriptomic responses after severe blunt traumatic injury with…”
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Protective immunity and defects in the neonatal and elderly immune response to sepsis
Published in The Journal of immunology (1950) (01-04-2014)“…Populations encompassing extremes of age, including neonates and elderly, have greater mortality from sepsis. We propose that the increased mortality observed…”
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Aged mice are unable to mount an effective myeloid response to sepsis
Published in The Journal of immunology (1950) (15-01-2014)“…The elderly have increased morbidity and mortality following sepsis; however, the cause(s) remains unclear. We hypothesized that these poor outcomes are due in…”
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Evolving paradigms in the nutritional support of critically ill surgical patients
Published in Current problems in surgery (01-04-2015)Get full text
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Host responses to sepsis vary in different low-lethality murine models
Published in PloS one (01-05-2014)“…Animal models for the study of sepsis are being increasingly scrutinized, despite their essential role for early translational research. In particular, recent…”
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Patterns of gene expression among murine models of hemorrhagic shock/trauma and sepsis
Published in Physiological genomics (01-02-2016)“…Controversy remains whether the leukocyte genomic response to trauma or sepsis is dependent upon the initiating stimulus. Previous work illustrated poor…”
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Successful implementation of a packed red blood cell and fresh frozen plasma transfusion protocol in the surgical intensive care unit
Published in PloS one (26-05-2015)“…Blood product transfusions are associated with increased morbidity and mortality. The purpose of this study was to determine if implementation of a restrictive…”
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Audiovisual Modules to Enhance Informed Consent in the ICU: A Pilot Study
Published in Critical care explorations (23-11-2020)“…Obtaining informed consent for commonly performed ICU procedures is often compromised by variability in communication styles and inadequate verbal descriptions…”
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Clostridium difficile Infections after Blunt Trauma: A Different Patient Population?
Published in Surgical infections (01-08-2015)“…The epidemiology of Clostridium difficile-associated infection (CDI) has changed, and it is evident that susceptibility is related not only to exposures and…”
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15
Current fistula management
Published in Current opinion in critical care (01-04-2024)“…Enterocutaneous fistulas (ECFs) pose a significant impact in the healthcare system, both financially and in resource utilization. Delivery of optimal care is…”
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Nutritional impact of omega 3 fatty acids and metabolites in acute and chronic critical illness
Published in Current opinion in clinical nutrition and metabolic care (01-03-2022)“…Lipids have been utilized historically as a calorie dense means to ensure delivery of essential fatty acids (FA). Since the development of mixed lipid emulsion…”
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678: Short-Course Antibiotic Therapy for Early Ventilator-Associated Pneumonia in Trauma Patients
Published in Critical care medicine (01-01-2021)Get full text
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Nutritional impact of omega 3 fatty acids and metabolites in acute and chronic critical illness
Published in Current opinion in clinical nutrition and metabolic care (03-02-2022)Get full text
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1038: ADULT MULTIDISCIPLINARY BOOT CAMP
Published in Critical care medicine (01-01-2020)Get full text
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575: Chronic Critically Ill Septic Patients Exhibit Persistent Expression of Proinflammatory Lipidomics
Published in Critical care medicine (01-01-2021)Get full text
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