Search Results - "Vansant, Gordon"

Case report: value of gene expression profiling in the diagnosis of atypical neuroblastoma by Harttrampf, Anne C, Chen, Qingrong, Jüttner, Eva, Geiger, Julia, Vansant, Gordon, Khan, Javed, Kontny, Udo

“…Nephroblastoma and neuroblastoma belong to the most common abdominal malignancies in childhood. Similarities in the initial presentation may provide…”
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Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid by Boyer, Jean D, Robinson, Tara M, Kutzler, Michele A, Vansant, Gordon, Hokey, David A, Kumar, Sanjeev, Parkinson, Rose, Wu, Ling, Sidhu, Maninder K, Pavlakis, George N, Felber, Barbara K, Brown, Charles, Silvera, Peter, Lewis, Mark G, Monforte, Joseph, Waldmann, Thomas A, Eldridge, John, Weiner, David B

“…The cell-mediated immune profile induced by a recombinant DNA vaccine was assessed in the simian/HIV (SHIV) and macaque model. The vaccine strategy included…”
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Gene Expression Profiling of Rat Livers Reveals Indicators of Potential Adverse Effects by Heinloth, Alexandra N., Irwin, Richard D., Boorman, Gary A., Nettesheim, Paul, Fannin, Rickie D., Sieber, Stella O., Snell, Michael L., Tucker, Charles J., Li, Leping, Travlos, Gregory S., Vansant, Gordon, Blackshear, Pamela E., Tennant, Raymond W., Cunningham, Michael L., Paules, Richard S.

“…This study tested the hypothesis that gene expression profiling can reveal indicators of subtle injury to the liver induced by a low dose of a substance that…”
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An Alu Element in the Myeloperoxidase Promoter Contains a Composite SP1-Thyroid Hormone-Retinoic Acid Response Element by Piedrafita, F J, Molander, R B, Vansant, G, Orlova, E A, Pfahl, M, Reynolds, W F

“…An Alu element preceding the myeloperoxidase gene ( MPO ) contains four hexamer motifs related to the consensus recognition sequence for nuclear hormone…”
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Diagnosis of the Small Round Blue Cell Tumors Using Multiplex Polymerase Chain Reaction by Chen, Qing-Rong, Vansant, Gordon, Oades, Kahuku, Pickering, Maria, Wei, Jun S, Song, Young K, Monforte, Joseph, Khan, Javed

“…The small round blue cell tumors of childhood, which include neuroblastoma, rhabdomyosarcoma, non-Hodgkin's lymphoma, and the Ewing's family of tumors, are so…”
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Quantification of activated and exhausted immune cell populations and simultaneous characterization of circulating tumor cells (CTCs) in peripheral blood of cancer patients receiving checkpoint inhibitor therapy by Vansant, Gordon, Krupa, Rachel, Richardson, Robin, Ontiveros, Priscilla, Byun, Jiyun, Landers, Mark, Dittamore, Ryan

“…Abstract only e14033 Background: Immune checkpoint inhibitors (ICIs) are becoming standard treatment options in many indications. However, a substantial…”
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Functional cell profiling (FCP) of ~100,000 CTCs from multiple cancer types identifies morphologically distinguishable CTC subtypes within and between cancer types by Vansant, Gordon, Jendrisak, Adam, Sutton, Ramsay, Orr, Sarah, Lu, David, Schonhoft, Joseph, Wang, Yipeng, Dittamore, Ryan

“…Abstract only e14553 Background: Different cancers subtypes can often be effectively treated with similar Rx classes (i.e. platinum or taxane Rx). Yet, within…”
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Abstract 3616: Low-pass whole-genome sequencing of single circulating tumor cells for detection of tumor mutation burden and chromosomal instability across multiple cancer types by Rodriguez, Angel, Lee, Jerry, Sutton, Ramsay, Jiles, Rhett, Vansant, Gordon, Wang, Yipeng, Landers, Mark, Dittamore, Ryan

“…Abstract Background: Recent studies show tumor mutation burden (TMB) is a biomarker for patient responses to immune checkpoint inhibitors whereas chromosomal…”
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Analysis of circulating tumor cells (CTCs) in patients across multiple metastatic breast cancer (mBCa) cohorts identifies marked inter- and intra-patient heterogeneity in CTC size, shape, and overall morphology by Vansant, Gordon, Wang, Yipeng, Hom, Beverly, Jendrisak, Adam, Schonhoft, Joseph, Graf, Ryon P, Ontiveros, Priscilla, Kearney, Megan, Landers, Mark Andrew, Dittamore, Ryan

“…Abstract only…”
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A single cell genomic signature to detect homologous recombination deficiency (HRD) and PARP inhibitors sensitivity using patient's circulating tumor cells (CTCs) by Vansant, Gordon, Dago, Angel E, Lee, Jerry, Greene, Stephanie, Lietz, Laura, Wang, Yipeng, Landers, Mark Andrew, Dittamore, Ryan Vance

“…Abstract only…”
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Involvement of the MADS-Box Gene ZMM4 in Floral Induction and Inflorescence Development in Maize by Danilevskaya, Olga N, Meng, Xin, Selinger, David A, Deschamps, Stéphane, Hermon, Pedro, Vansant, Gordon, Gupta, Rajeev, Ananiev, Evgueni V, Muszynski, Michael G

“…The switch from vegetative to reproductive growth is marked by the termination of vegetative development and the adoption of floral identity by the shoot…”
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Exploring molecular pathways of triple-negative breast cancer by Ossovskaya, Valeria, Wang, Yipeng, Budoff, Adam, Xu, Qiang, Lituev, Alexander, Potapova, Olga, Vansant, Gordon, Monforte, Joseph, Daraselia, Nikolai

“…Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with a high rate of proliferation and metastasis, as well as poor prognosis for…”
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NGS-based targeted RNA sequencing for expression profiling and relative quantitation of specific gene isoforms and fusions in tumor-specific panels by Vansant, Gordon, Landers, Mark, Vo, Lien, Oades, Kahuku, Kim, Hyunsoo, Lee, Jerry, Meredith, Rhonda, Lee, Byung-In, Monforte, Joseph

“…Abstract only 11108 Background: Gene expression signatures have become a useful tool for the identification of tumor subtypes and response to specific…”
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Molecular signature and pathway analysis of human primary squamous and adenocarcinoma lung cancers by Daraselia, Nikolai, Wang, Yipeng, Budoff, Adam, Lituev, Alexander, Potapova, Olga, Vansant, Gordon, Monforte, Joseph, Mazo, Ilya, Ossovskaya, Valeria S

“…Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, with a poor response to chemotherapy and low survival rate. This unfavorable…”
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Abstract LB-224: Development of a novel breast cancer segregation panel assay for multiple genetic subtyping based on gene expression modules developed from Oncomine by Oades, Kahuku, Chattopadhyay, Sukla, Kim, Hyunsoo, Vo, Lien, Telford, David, Wang, Yipeng, Lee, Byung-in, Monforte, Joseph, Vansant, Gordon, Freshley, John, Wyngaard, Peter, Rhodes, Daniel, Tomlins, Scott

“…Abstract Breast cancer is a highly heterogeneous disease as evidenced by comprehensive genetic studies which have revealed multiple subtypes using gene…”
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Myosin VIIa, the product of the Usher 1B syndrome gene, is concentrated in the connecting cilia of photoreceptor cells by Liu, Xinran, Vansant, Gordon, Udovichenko, Igor P., Wolfrum, Uwe, Williams, David S.

“…Usher syndrome is the most common form of combined deafness and blindness. The gene that is defective in Usher syndrome 1B (USH1B) encodes for an…”
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Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts by Monks, Anne, Hose, Curtis D, Pezzoli, Patrick, Kondapaka, Sudhir, Vansant, Gordon, Petersen, Kamille Dumong, Sehested, Maxwell, Monforte, Joseph, Shoemaker, Robert H

“…Belinostat is a hydroxamate-type histone deactylase inhibitor (HDACi), which has recently entered phase I and II clinical trials. Microarray-based analysis of…”
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High-throughput toxicological classification of candidate drug compounds using gene expression, evolved neural networks, and a cell-based platform by Vansant, Gordon, Pezzoli, Pat, Monforte, Joseph, Fogel, Gary B.

“…All new pharmaceutical agents must be screened for potential toxicity in humans. This process includes a series of genotoxic screens in the discovery phase,…”
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Involvement of the MADS-Box Gene ZMM4 in Floral Induction and Inflorescence Development in Maizea by Danilevskaya, Olga N., Meng, Xin, Selinger, David A., Deschamps, Stéphane, Hermon, Pedro, Vansant, Gordon, Gupta, Rajeev, Ananiev, Evgueni V., Muszynski, Michael G.

“…The switch from vegetative to reproductive growth is marked by the termination of vegetative development and the adoption of floral identity by the shoot…”
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The Consensus Sequence of a Major Alu Subfamily Contains a Functional Retinoic Acid Response Element by Vansant, Gordon, Reynolds, Wanda F.

“…Alu repeats are interspersed repetitive DNA elements specific to primates that are present in 500,000 to 1 million copies. We show here that an Alu sequence…”
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