Search Results - "Vannini, Ivan"
-
1
Linear and circular PVT1 in hematological malignancies and immune response: two faces of the same coin
Published in Molecular cancer (30-03-2020)“…Non coding RNAs (ncRNAs) have emerged as regulators of human carcinogenesis by affecting the expression of key tumor suppressor genes and oncogenes. They are…”
Get full text
Journal Article -
2
Overexpression of ultraconserved region 83- induces lung cancer tumorigenesis
Published in PloS one (11-01-2022)“…The expression of non-coding RNAs (ncRNAs) is dysregulated in human cancers. The transcribed ultraconserved regions (T-UCRs) express long ncRNAs involved in…”
Get full text
Journal Article -
3
Non-Coding RNAs in Retinoblastoma
Published in Frontiers in genetics (14-11-2019)“…Retinoblastoma (Rb) is the most common ocular pediatric malignancy that arises from the retina and is caused by a mutation of the two alleles of the tumor…”
Get full text
Journal Article -
4
Exosome-mediated transfer of microRNAs within the tumor microenvironment and neuroblastoma resistance to chemotherapy
Published in JNCI : Journal of the National Cancer Institute (01-07-2015)“…How exosomic microRNAs (miRNAs) contribute to the development of drug resistance in the context of the tumor microenvironment has not been previously described…”
Get full text
Journal Article -
5
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis
Published in Gut (01-06-2016)“…MicroRNA (miRNA) expression profile can be used as prognostic marker for human cancers. We aim to explore the significance of miRNAs in colorectal cancer (CRC)…”
Get more information
Journal Article -
6
Modulation of mismatch repair and genomic stability by miR-155
Published in Proceedings of the National Academy of Sciences - PNAS (13-04-2010)“…Inactivation of mismatch repair (MMR) is the cause of the common cancer predisposition disorder Lynch syndrome (LS), also known as hereditary nonpolyposis…”
Get full text
Journal Article -
7
Strand-Specific miR-28-5p and miR-28-3p Have Distinct Effects in Colorectal Cancer Cells
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2012)“…Background & Aims MicroRNAs (miRNAs) can promote or inhibit tumor growth and are therefore being developed as targets for cancer therapies. They are diverse…”
Get full text
Journal Article -
8
Extra Virgin Olive Oil (EVOO), a Mediterranean Diet Component, in the Management of Muscle Mass and Function Preservation
Published in Nutrients (30-08-2022)“…Aging results in a progressive decline in skeletal muscle mass, strength and function, a condition known as sarcopenia. This pathological condition is due to…”
Get full text
Journal Article -
9
The Cytotoxic Effect of Curcumin in Rhabdomyosarcoma Is Associated with the Modulation of AMPK, AKT/mTOR, STAT, and p53 Signaling
Published in Nutrients (01-02-2023)“…Approximately 7% of cancers arising in children and 1% of those arising in adults are soft tissue sarcomas (STS). Of these malignancies, rhabdomyosarcoma (RMS)…”
Get full text
Journal Article -
10
MicroRNA-16 Restores Sensitivity to Tyrosine Kinase Inhibitors and Outperforms MEK Inhibitors in KRAS -Mutated Non-Small Cell Lung Cancer
Published in International journal of molecular sciences (12-12-2021)“…Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide. Chemotherapy, the treatment of choice in non-operable cases, achieves a…”
Get full text
Journal Article -
11
Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs
Published in Nature communications (27-11-2017)“…The transcribed ultraconserved regions (T-UCRs) encode long non-coding RNAs implicated in human carcinogenesis. Their mechanisms of action and the factors…”
Get full text
Journal Article -
12
Uncovering the expression of circPVT1 in the extracellular vesicles of acute myeloid leukemia patients
Published in Biomedicine & pharmacotherapy (01-09-2023)“…Extracellular vesicles (EVs) act as molecular mediators in the tumor microenvironment, by shuttling information contained within malignant cells and…”
Get full text
Journal Article -
13
microRNAs in the tumor microenvironment: solving the riddle for a better diagnostics
Published in Expert review of molecular diagnostics (01-06-2014)“…miRNAs are small noncoding RNAs with gene regulatory functions, frequently dysregulated in human cancers. Specific signatures of differentially expressed…”
Get more information
Journal Article -
14
Comparative Analysis of Free-Circulating and Vesicle-Associated Plasma microRNAs of Healthy Controls and Early-Stage Lung Cancer Patients
Published in Pharmaceutics (23-09-2022)“…In recent years, circulating extracellular miRNAs have emerged as a useful tool for the molecular characterization and study of tumors’ biological functions…”
Get full text
Journal Article -
15
Clinical Implications of MicroRNAs in Lung Cancer
Published in Seminars in oncology (01-12-2011)“…Lung cancer still represents a very deadly disease in strong need of new, effective, therapeutic approaches. MicroRNAs (miRNAs) represent a new category of…”
Get full text
Journal Article -
16
Analysis of EVs from patients with advanced pancreatic cancer identifies antigens and miRNAs with predictive value
Published in Molecular therapy. Methods & clinical development (08-06-2023)“…The identification of predictive factors for treatment of pancreatic cancer (PC) is an unmet clinical need. In the present work, we analyzed blood-derived…”
Get full text
Journal Article -
17
Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines
Published in Journal of cellular physiology (01-07-2009)“…Sorafenib is a multikinase inhibitor that has shown promising therapeutic results in different tumor histotypes, both as a single agent or in combination with…”
Get full text
Journal Article -
18
miR-9-5p as a Regulator of the Androgen Receptor Pathway in Breast Cancer Cell Lines
Published in Frontiers in cell and developmental biology (12-11-2020)“…Breast cancer (BC) is the most diagnosed carcinoma and the leading cause of cancer death in female over 100 countries. Thanks to the advance in therapeutic…”
Get full text
Journal Article -
19
Case Report: Analysis of Plasma Extracellular Vesicles in a Triple Negative Spindle-Cell Metaplastic Breast Cancer Patient
Published in Frontiers in medicine (09-03-2022)“…Metaplastic breast cancer (MpBC) is a rare tumor representing 1% of all breast malignancies. The prognosis of this histologic subtype is actually poor and…”
Get full text
Journal Article -
20
Early Detection and Investigation of Extracellular Vesicles Biomarkers in Breast Cancer
Published in Frontiers in molecular biosciences (08-11-2021)“…Breast cancer (BC) is the most commonly diagnosed malignant tumor in women worldwide, and the leading cause of cancer death in the female population. The…”
Get full text
Journal Article