Search Results - "Vanmolkot, Floris H M"
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Inhibition of capsaicin‐induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK‐0974)
Published in British journal of clinical pharmacology (01-01-2010)“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Calcitonin gene‐related peptide (CGRP) was first described as a potent vasodilator. • CGRP is also increasingly…”
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A control systems approach to quantify wall shear stress normalization by flow-mediated dilation in the brachial artery
Published in PloS one (18-02-2015)“…Flow-mediated dilation is aimed at normalization of local wall shear stress under varying blood flow conditions. Blood flow velocity and vessel diameter are…”
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Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
Published in Neurology (16-04-2019)“…OBJECTIVETo identify a plasma metabolomic biomarker signature for migraine. METHODSPlasma samples from 8 Dutch cohorts (n = 10,1532,800 migraine patients and…”
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Reproducibility of forearm vasodilator response to intra‐arterial infusion of calcitonin gene‐related peptide assessed by venous occlusion plethysmography
Published in British journal of clinical pharmacology (01-04-2005)“…Aims To assess the reproducibility of the forearm blood flow (FBF) response to intra‐arterial infusion of calcitonin‐gene related peptide (CGRP), measured by…”
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5
Acute effects of sumatriptan on aortic blood pressure, stiffness, and pressure waveform
Published in Clinical pharmacology and therapeutics (01-07-2006)“…Background and Objectives Sumatriptan, a 5‐hydroxytryptamine (HT)1B/1D receptor agonist, is an effective acute antimigraine drug. Because of its…”
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Calcitonin gene–related peptide–induced vasodilation in the human forearm is antagonized by CGRP8‐37: Evaluation of a human in vivo pharmacodynamic model
Published in Clinical pharmacology and therapeutics (01-03-2006)“…Objectives The aims of this study were to assess the potential of CGRP8–37, the C‐terminal fragment of calcitonin gene–related peptide (CGRP), to inhibit…”
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Labtracker+, a medical smartphone app for the interpretation of consecutive laboratory results: an external validation study
Published in BMJ open (01-09-2017)“…ObjectivesWhen monitoring patients over time, clinicians may struggle to distinguish ‘real changes’ in consecutive blood parameters from so-called natural…”
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PCSK9 inhibitors; who benefits from these new cholesterol-lowering drugs?
Published in Nederlands tijdschrift voor geneeskunde (16-01-2020)“…PCSK9 inhibitors are monoclonal antibodies that target the protein PCSK9. These drugs (alirocumab and evolcumab) are a new generation of cholesterol-lowering…”
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