Search Results - "Vankova, M"
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Insights into the physiology of C-peptide
Published in Physiological research (01-09-2020)“…Current knowledge suggests a complex role of C-peptide in human physiology, but its mechanism of action is only partially understood. The effects of C-peptide…”
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Distinct response of fat and gastrointestinal tissue to glucose in gestational diabetes mellitus and polycystic ovary syndrome
Published in Physiological research (01-01-2017)“…Gestational diabetes mellitus (GDM) and polycystic ovary syndrome (PCOS) are distinct pathologies with impaired insulin sensitivity as a common feature. The…”
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Genetic predictors of the development and recurrence of Graves' disease
Published in Physiological research (01-01-2018)“…Graves' disease affects approximately 3 % of women and 0.5 % of men. The first-choice therapy is based on the administration of thyrostatic drugs. However,…”
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Specific metabolic characteristics of women with former gestational diabetes: the importance of adipose tissue
Published in Physiological research (01-01-2017)“…Women with a positive history of gestational diabetes mellitus (GDM) face a higher risk of developing type 2 diabetes mellitus (T2DM) and metabolic syndrome…”
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Short communication: Usage of mechanical brushes by lactating dairy cows
Published in Journal of dairy science (01-05-2007)“…The objective of this experiment was to investigate how the provision of a mechanical brush affects the grooming (scratching) behavior of group-housed dairy…”
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Gestational diabetes - metabolic risks of adult women with respect to birth weight
Published in Physiological research (01-01-2015)“…Metabolic disorders such as obesity, insulin resistance and other components of metabolic syndrome (MetS) are connected with birth weight. Low and high birth…”
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ZBTB16 and metabolic syndrome: a network perspective
Published in Physiological research (01-01-2017)“…Metabolic syndrome is a prevalent, complex condition. The search for genetic determinants of the syndrome is currently undergoing a paradigm enhancement by…”
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The UCP1 gene polymorphism A-3826G in relation to DM2 and body composition in Czech population
Published in Experimental and clinical endocrinology & diabetes (01-05-2007)“…Mitochondrial uncoupling contributes to the control of energy expenditure. The brown fat specific uncoupling protein 1 (UCP1) mRNA was detected in…”
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ZBTB16 gene variability influences obesity-related parameters and serum lipid levels in Czech adults
Published in Physiological research (01-01-2017)“…The data derived from rat models and the preliminary results of human studies provide strong indices of involvement of common ZBTB16 variants in a range of…”
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T2D risk haplotypes of the TCF7L2 gene in the Czech population sample: the association with free fatty acids composition
Published in Physiological research (01-01-2012)“…The association of transcription factor 7-like 2 (TCF7L2) gene variants with the pathogenesis of T2D, gestational diabetes and polycystic ovary syndrome (PCOS)…”
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Associations of polymorphisms in the candidate genes for Alzheimer’s disease BIN1, CLU, CR1 and PICALM with gestational diabetes and impaired glucose tolerance
Published in Molecular biology reports (01-04-2017)“…Alzheimer’s disease (AD) is the most common type of dementia, with a prevalence that is rising every year. AD is associated with type 2 diabetes mellitus…”
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Feasibility of implementation of the early tumor shrinkage as a potential predictive marker to daily clinical practice in patients with RAS wild type metastatic colorectal cancer, treated with cetuximab - a non-interventional observational study
Published in Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti (2024)“…With the aim to show the feasibility of early tumor shrinkage (ETS) concept implementation into daily clinical practice in the Czech Republic, a…”
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Reduced sulfotransferase SULT2A1 activity in patients with Alzheimer's disease
Published in Physiological research (2015)“…Steroids are important components in the pathophysiology of Alzheimer's disease (AD). Although their role has been studied, the corresponding metabolomic data…”
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Metabolic and hormonal consequencies of the "obesity risk" MC4R variant (rs12970134) in Czech women
Published in Physiological research (01-01-2015)“…Although the mutations in MC4R gene became known as the most common genetic cause of human obesity, the effect of rs12970134 A/G near MC4R gene on insulin…”
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Plasma levels of adipokines in patients with Alzheimer's disease - where is the "breaking point" in Alzheimer's disease pathogenesis?
Published in Physiological research (01-09-2020)“…Peripheral insulin resistance is associated with decreasing adiponectin and increasing leptin plasma levels, and also with cognitive decline. The effects of…”
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The differences between aromatizable and non-aromatizable androgens in relation to body composition and metabolic syndrome risk factors in men
Published in The Journal of steroid biochemistry and molecular biology (01-10-2012)“…► No difference between aromatizable and non-aromatizable steroids. ► The associations of testosterone and dihydrotestosterone are equally strong in quality…”
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Role of central mu, delta-1, and kappa-1 opioid receptors in opioid-induced muscle rigidity in the rat
Published in Anesthesiology (Philadelphia) (01-09-1996)“…Opioids appear to produce their physiologic effects by binding to at least three types of opioid receptors, the mu (mu), delta (delta), and kappa (kappa)…”
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Fat mass and obesity associated gene variants are associated with increased growth hormone levels and affect glucose and lipid metabolism in lean women
Published in Physiological research (2015)“…First intron variability of the fat mass and obesity associated gene (FTO) has strong impact on adiposity. We focused on lean women carrying the most…”
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Fat Mass and Obesity Associated Gene Variants Are Associated With Increased Growth Hormone Levels and Affect Glucose and Lipid Metabolism in Lean Women
Published in Physiological research (2015)“…First intron variability of the fat mass and obesity associated gene (FTO) has strong impact on adiposity. We focused on lean women carrying the most…”
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