Search Results - "Vanková, M"

Fat Mass and Obesity Associated Gene Variants Are Associated With Increased Growth Hormone Levels and Affect Glucose and Lipid Metabolism in Lean Women by LUKÁŠOVÁ, P., VAŇKOVÁ, M., VČELÁK, J., VEJRAŽKOVÁ, D., BRADNOVÁ, O., STANICKÁ, S., HAINER, V., BENDLOVÁ, B.

“…First intron variability of the fat mass and obesity associated gene (FTO) has strong impact on adiposity. We focused on lean women carrying the most…”
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ZBTB16 and metabolic syndrome: a network perspective by Šeda, O, Šedová, L, Včelák, J, Vaňková, M, Liška, F, Bendlová, B

“…Metabolic syndrome is a prevalent, complex condition. The search for genetic determinants of the syndrome is currently undergoing a paradigm enhancement by…”
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What may be the markers of the male equivalent of polycystic ovary syndrome? by Dusková, M, Cermáková, I, Hill, M, Vanková, M, Sámalíková, P, Stárka, L

“…Polycystic ovary syndrome (PCOS), the most common endocrinopathy in women (with a prevalence of 5-10 %), is characterized by hormonal and metabolic imbalance…”
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Hydrogen peroxide production by alveolar macrophages is increased and its concentration is elevated in the breath of rats exposed to hypoxia: relationship to lung lipid peroxidation by Wilhelm, J, Vanková, M, Maxová, H, Sisková, A

“…Hypoxic exposure triggers a generation of reactive oxygen species that initiate free radical damage to the lung. Hydrogen peroxide is the product of alveolar…”
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ZBTB16 gene variability influences obesity-related parameters and serum lipid levels in Czech adults by Bendlová, B, Vaňková, M, Hill, M, Vacínová, G, Lukášová, P, VejraŽková, D, Šedová, L, Šeda, O, Včelák, J

“…The data derived from rat models and the preliminary results of human studies provide strong indices of involvement of common ZBTB16 variants in a range of…”
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Insights into the physiology of C-peptide by Vejrazkova, D, Vankova, M, Lukasova, P, Vcelak, J, Bendlova, B

“…Current knowledge suggests a complex role of C-peptide in human physiology, but its mechanism of action is only partially understood. The effects of C-peptide…”
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Distinct response of fat and gastrointestinal tissue to glucose in gestational diabetes mellitus and polycystic ovary syndrome by Vejrazkova, D, Lischkova, O, Vankova, M, Stanicka, S, Vrbikova, J, Lukasova, P, Vcelak, J, Vacinova, G, Bendlova, B

“…Gestational diabetes mellitus (GDM) and polycystic ovary syndrome (PCOS) are distinct pathologies with impaired insulin sensitivity as a common feature. The…”
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T2D risk haplotypes of the TCF7L2 gene in the Czech population sample: the association with free fatty acids composition by Včelák, J, Vejražková, D, Vaňková, M, Lukášová, P, Bradnová, O, Hálková, T, Bešťák, J, Andělová, K, Kvasničková, H, Hoskovcová, P, Vondra, K, Vrbíková, J, Bendlová, B

“…The association of transcription factor 7-like 2 (TCF7L2) gene variants with the pathogenesis of T2D, gestational diabetes and polycystic ovary syndrome (PCOS)…”
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Role of intron 5 C/T polymorphism of the calcium sensing receptor gene in the regulation of the serum FSH and LH in post-menopausal women by Zofková, I, Zajícková, K, Hill, M, Vanková, M

“…High extracellular calcium concentration (Cao(2+)) acts to inhibit calcium sensing receptor (CaR) signalling on cellular surfaces in parathyroid glands. This…”
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Associations of polymorphisms in the candidate genes for Alzheimer’s disease BIN1, CLU, CR1 and PICALM with gestational diabetes and impaired glucose tolerance by Vacínová, Gabriela, Vejražková, D., Lukášová, P., Lischková, O., Dvořáková, K., Rusina, R., Holmerová, I., Vaňková, H., Včelák, J., Bendlová, B., Vaňková, M.

“…Alzheimer’s disease (AD) is the most common type of dementia, with a prevalence that is rising every year. AD is associated with type 2 diabetes mellitus…”
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Feasibility of implementation of the early tumor shrinkage as a potential predictive marker to daily clinical practice in patients with RAS wild type metastatic colorectal cancer, treated with cetuximab - a non-interventional observational study by Fínek, J, Vočka, M, Bauer, J, Kubala, E, Zycháčková, K, Šedivá, M, Gharibyar, M, Kocáková, I, Čmuchařová, E, Vaňková, M

“…With the aim to show the feasibility of early tumor shrinkage (ETS) concept implementation into daily clinical practice in the Czech Republic, a…”
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Genetic predictors of the development and recurrence of Graves' disease by Vejrazkova, D, Vcelak, J, Vaclavikova, E, Vankova, M, Zajickova, K, Duskova, M, Vrbikova, J, Bendlova, B

“…Graves' disease affects approximately 3 % of women and 0.5 % of men. The first-choice therapy is based on the administration of thyrostatic drugs. However,…”
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Reduced sulfotransferase SULT2A1 activity in patients with Alzheimer's disease by Vaňková, M, Hill, M, Velíková, M, Včelák, J, Vacínová, G, Lukášová, P, Vejražková, D, Dvořáková, K, Rusina, R, Holmerová, I, Jarolímová, E, Vaňková, H, Bendlová, B

“…Steroids are important components in the pathophysiology of Alzheimer's disease (AD). Although their role has been studied, the corresponding metabolomic data…”
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Metabolic and hormonal consequencies of the "obesity risk" MC4R variant (rs12970134) in Czech women by Bradnová, O, Vejražková, D, Vaňková, M, Lukášová, P, Včelák, J, Stanická, S, Dvořáková, K, Bendlová, B

“…Although the mutations in MC4R gene became known as the most common genetic cause of human obesity, the effect of rs12970134 A/G near MC4R gene on insulin…”
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Plasma levels of adipokines in patients with Alzheimer's disease - where is the "breaking point" in Alzheimer's disease pathogenesis? by Vaňková, M, Vacínová, G, Včelák, J, Vejražková, D, Lukášová, P, Rusina, R, Holmerová, I, Jarolímová, E, Vaňková, H, Bendlová, B

“…Peripheral insulin resistance is associated with decreasing adiponectin and increasing leptin plasma levels, and also with cognitive decline. The effects of…”
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Specific metabolic characteristics of women with former gestational diabetes: the importance of adipose tissue by Vejrazkova, D, Vankova, M, Lukasova, P, Vcelak, J, Cirmanova, V, Haluzik, M, Bendlova, B

“…Women with a positive history of gestational diabetes mellitus (GDM) face a higher risk of developing type 2 diabetes mellitus (T2DM) and metabolic syndrome…”
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Ultrastructural localisation of calcium deposits in the mouse ovary by Sedmíková, M, Rajmon, R, Petr, J, Vanková, M, Rozinek, J, Rehák, D, Jílek, F

“…Follicle-enclosed mouse oocytes contain numerous calcium deposits. The ultrastructural distribution of calcium deposits in the nuclei, mitochondria and…”
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Polymorphism of INS VNTR is associated with glutamic acid decarboxylase antibodies and postprandial C-peptide in patients with onset of diabetes after 35 years of age by Matejková-Behanová, M, Vanková, M, Hill, M, Kucera, P, Cinek, O, Andel, M, Bendlová, B

“…Variability in the number of tandem repeats of the insulin gene (INS VNTR) is probably involved in the genetic regulation of insulin secretion. The aim of this…”
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The differences between aromatizable and non-aromatizable androgens in relation to body composition and metabolic syndrome risk factors in men by Pospíšilová, H., Vaňková, M., Hill, M., Meloun, M., Bendlová, B., Dušková, M., Stárka, L.

“…► No difference between aromatizable and non-aromatizable steroids. ► The associations of testosterone and dihydrotestosterone are equally strong in quality…”
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Metabolic Syndrome, Polycystic Ovary Syndrome and the Importance of Being Earnest in Defining the Most Common Endocrine Diseases. and Let’s Not Forget About Men – They Are Also Important by Boyanov, M., Vankova, M.

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