Search Results - "Vanhie, Arne"
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Development of organoids from mouse and human endometrium showing endometrial epithelium physiology and long-term expandability
Published in Development (Cambridge) (15-05-2017)“…The endometrium, which is of crucial importance for reproduction, undergoes dynamic cyclic tissue remodeling. Knowledge of its molecular and cellular…”
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Progesterone Receptor Status Predicts Response to Progestin Therapy in Endometriosis
Published in The journal of clinical endocrinology and metabolism (01-12-2018)“…Progestin-based therapy is the first-line treatment for managing endometriosis-associated pain. However, response to progestins is currently variable and…”
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Functional expression of the mechanosensitive PIEZO1 channel in primary endometrial epithelial cells and endometrial organoids
Published in Scientific reports (11-02-2019)“…Successful pregnancy requires the establishment of a complex dialogue between the implanting embryo and the endometrium. Knowledge regarding molecular…”
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The Effect of Endurance Exercise on Semen Quality in Male Athletes: A Systematic Review
Published in Sports medicine - open (11-06-2024)“…Background Endurance exercise has the potential to affect reproductive function, with amenorrhea in female athletes. However, most studies focus on women…”
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Endometriosis is associated with aberrant metabolite profiles in plasma
Published in Fertility and sterility (01-03-2017)“…Objective To identify metabolites that are associated with and predict the presence of endometriosis. Design Metabolomics study using state-of-the-art mass…”
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Functional Expression of TRP Ion Channels in Endometrial Stromal Cells of Endometriosis Patients
Published in International journal of molecular sciences (21-08-2018)“…Endometriosis is a common gynecological disease that is characterized by the presence of functional endometrial-like lesions in the abdominal cavity. Aside…”
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Circulating microRNAs as Non-Invasive Biomarkers in Endometriosis Diagnosis-A Systematic Review
Published in Biomedicines (01-04-2024)“…The aim of this systematic review is to assess the power of circulating miRNAs as biomarkers as a diagnostic tool in endometriosis. In endometriosis-suspected…”
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Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening
Published in Nature cell biology (01-08-2019)“…Endometrial disorders represent a major gynaecological burden. Current research models fail to recapitulate the nature and heterogeneity of these diseases,…”
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The prevalence of endometriosis in unexplained infertility: a systematic review
Published in Reproductive biomedicine online (01-09-2024)“…In 15–30% of couples with infertility, no abnormalities are found after the initial diagnostic work-up. The aim of this study was to investigate the prevalence…”
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Perspectives of preimplantation genetic testing patients in Belgium on the ethics of polygenic embryo screening
Published in Reproductive biomedicine online (01-09-2024)“…•The use of polygenic risk scores for embryo selection is ethically contentious•Patients in Belgium undergoing PGT for monogenic/single-gene disorders or…”
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An irreversible inhibitor of 17β-hydroxysteroid dehydrogenase type 1 inhibits estradiol synthesis in human endometriosis lesions and induces regression of the non-human primate endometriosis
Published in The Journal of steroid biochemistry and molecular biology (01-09-2022)“…Endometriosis is a gynecological disorder affecting about 10% of women and can lead to invalidating painful symptoms and infertility. Since there is no current…”
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Preclinical workup using long-read amplicon sequencing provides families with de novo pathogenic variants access to universal preimplantation genetic testing
Published in Human reproduction (Oxford) (01-03-2023)“…Can long-read amplicon sequencing be beneficial for preclinical preimplantation genetic testing (PGT) workup in couples with a de novo pathogenic variant in…”
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The Use of Antibody Arrays in the Discovery of New Plasma Biomarkers for Endometriosis
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-02-2020)“…A noninvasive diagnostic test for endometriosis is needed to shorten the current diagnostic delay of 8-11 years. The goal of this study was to discover new…”
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Endometriosis biomarkers: Will codevelopment in academia–industry partnerships result in new and robust noninvasive diagnostic tests?
Published in Biology of reproduction (24-12-2019)“…Endometriosis is an important gynecological disease, affecting 10% of reproductive age women, and associated with pain, infertility, reduced quality of life,…”
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Challenges in the development of novel therapeutic strategies for treatment of endometriosis
Published in Expert opinion on therapeutic targets (03-05-2016)“…Endometriosis is an estrogen-dependent disease that results in pelvic pain and infertility. Its treatment is often frustrating due to limited medical treatment…”
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Focal what focal? - The diverse entities within focal adenomyosis
Published in Journal of endometriosis and uterine disorders (01-11-2024)Get full text
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The Presence of Endometrial Cells in Peritoneal Fluid of Women With and Without Endometriosis
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-02-2017)“…To reinforce Sampson's theory of retrograde menstruation in the pathogenesis of endometriosis, proof should be provided that during menstruation endometrial…”
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An irreversible inhibitor of 17β-hydroxysteroid dehydrogenase type 1 inhibits estradiol synthesis in human endometriosis lesions and induces regression of the non-human primate endometriosis model
Published in The Journal of steroid biochemistry and molecular biology (09-06-2022)“…Endometriosis is a gynecological disorder affecting about 10% of women and can lead to invalidating painful symptoms and infertility. Since there is no…”
Get full text
Journal Article