Search Results - "Vanhee, Peter"

PepX: a structural database of non-redundant protein-peptide complexes by Vanhee, Peter, Reumers, Joke, Stricher, Francois, Baeten, Lies, Serrano, Luis, Schymkowitz, Joost, Rousseau, Frederic

“…Although protein-peptide interactions are estimated to constitute up to 40% of all protein interactions, relatively little information is available for the…”
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BriX: a database of protein building blocks for structural analysis, modeling and design by Vanhee, Peter, Verschueren, Erik, Baeten, Lies, Stricher, Francois, Serrano, Luis, Rousseau, Frederic, Schymkowitz, Joost

“…High-resolution structures of proteins remain the most valuable source for understanding their function in the cell and provide leads for drug design. Since…”
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Protein-Peptide Interactions Adopt the Same Structural Motifs as Monomeric Protein Folds by Vanhee, Peter, Stricher, Francois, Baeten, Lies, Verschueren, Erik, Lenaerts, Tom, Serrano, Luis, Rousseau, Frederic, Schymkowitz, Joost

“…We compared the modes of interaction between protein-peptide interfaces and those observed within monomeric proteins and found surprisingly few differences…”
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The multiple‐specificity landscape of modular peptide recognition domains by Gfeller, David, Butty, Frank, Wierzbicka, Marta, Verschueren, Erik, Vanhee, Peter, Huang, Haiming, Ernst, Andreas, Dar, Nisa, Stagljar, Igor, Serrano, Luis, Sidhu, Sachdev S, Bader, Gary D, Kim, Philip M

“…Modular protein interaction domains form the building blocks of eukaryotic signaling pathways. Many of them, known as peptide recognition domains, mediate…”
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Modeling protein-peptide interactions using protein fragments: fitting the pieces? by Vanhee, Peter, Stricher, Francois, Baeten, Lies, Verschueren, Erik, Serrano, Luis, Rousseau, Frederic, Schymkowitz, Joost

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Protein-Peptide Complex Prediction through Fragment Interaction Patterns by Verschueren, Erik, Vanhee, Peter, Rousseau, Frederic, Schymkowitz, Joost, Serrano, Luis

“…The number of protein-peptide interactions in a cell is so large that experimental determination of all these complex structures would be a daunting task…”
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SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants by De Baets, Greet, Van Durme, Joost, Reumers, Joke, Maurer-Stroh, Sebastian, Vanhee, Peter, Dopazo, Joaquin, Schymkowitz, Joost, Rousseau, Frederic

“…Single nucleotide variants (SNVs) are, together with copy number variation, the primary source of variation in the human genome and are associated with…”
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Computational design of peptide ligands by Vanhee, Peter, van der Sloot, Almer M, Verschueren, Erik, Serrano, Luis, Rousseau, Frederic, Schymkowitz, Joost

“…Peptides possess several attractive features when compared to small molecule and protein therapeutics, such as high structural compatibility with target…”
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Protein design with fragment databases by Verschueren, Erik, Vanhee, Peter, van der Sloot, Almer M, Serrano, Luis, Rousseau, Frederic, Schymkowitz, Joost

“…► Casting protein structures in fragment libraries reveals structural symmetries. ► Current databases cover the known variation in regular secondary structure…”
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SAPIN: A framework for the structural analysis of protein interaction networks by YANG, Jae-Seong, CAMPAGNA, Anne, DELGADO, Javier, VANHEE, Peter, SERRANO, Luis, KIEL, Christina

“…Protein interaction networks are widely used to depict the relationships between proteins. These networks often lack the information on physical binary…”
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Unusual outcome of in utero infection and subsequent postnatal super-infection with different PCV2b strains by Saha, Dipongkor, Karniychuk, Uladzimir U., Huang, Liping, Geldhof, Marc, Vanhee, Merijn, Lefebvre, David J., Meerts, Peter, Ducatelle, Richard, Doorsselaere, Jan V., Nauwynck, Hans J.

“…VC2002, isolated from postweaning multisystemic wasting syndrome（PMWS）-affected pig, is a mixture of two porcine circovirus genotype 2b（PCV2b） viruses, K2 and…”
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