Search Results - "Vangipuram, Kiran"
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Paclitaxel Plasma Concentration after the First Infusion Predicts Treatment-Limiting Peripheral Neuropathy
Published in Clinical cancer research (01-08-2018)“…Paclitaxel exposure, specifically the maximum concentration ( ) and amount of time the concentration remains above 0.05 μmol/L ( ), has been associated with…”
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Reporting of paclitaxel-induced peripheral neuropathy symptoms to clinicians among women with breast cancer: a qualitative study
Published in Supportive care in cancer (01-09-2020)“…Purpose Cases of chemotherapy-induced peripheral neuropathy (CIPN) under-reporting have been sporadically described in the literature, but no studies have…”
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Pharmacometabolomics reveals a role for histidine, phenylalanine, and threonine in the development of paclitaxel-induced peripheral neuropathy
Published in Breast cancer research and treatment (01-10-2018)“…Purpose Approximately 25% of breast cancer patients experience treatment delays or discontinuation due to paclitaxel-induced peripheral neuropathy (PN)…”
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Vitamin D deficiency increases severity of paclitaxel-induced peripheral neuropathy
Published in Breast cancer research and treatment (01-04-2020)“…Purpose Approximately 25% of patients receiving weekly paclitaxel for breast cancer require treatment disruptions to avoid severe, irreversible peripheral…”
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Patient factors associated with discrepancies between patient-reported and clinician-documented peripheral neuropathy in women with breast cancer receiving paclitaxel: A pilot study
Published in Breast (Edinburgh) (01-06-2020)“…Discrepancies between clinicians’ assessment of chemotherapy-induced peripheral neuropathy (CIPN) and patient-reported outcomes (PRO) have been described,…”
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Genetic variation in EPHA contributes to sensitivity to paclitaxel‐induced peripheral neuropathy
Published in British journal of clinical pharmacology (01-05-2020)“…Aims Chemotherapy‐induced peripheral neuropathy (PN) is a treatment limiting toxicity of paclitaxel. We evaluated if EPHA genetic variation (EPHA4, EPHA5,…”
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EPHA genetics for prediction of paclitaxel-induced peripheral neuropathy sensitivity
Published in Journal of clinical oncology (20-05-2019)“…Abstract only 532 Background: Chemotherapy induced peripheral neuropathy (CIPN) is a common, debilitating paclitaxel side effect that has been primarily…”
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Vitamin D insufficiency and risk of paclitaxel-induced peripheral neuropathy
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e12027 Background: Peripheral neuropathy (PN) is a severe, dose-limiting toxicity of paclitaxel that occurs in up to 25% of patients and can lead…”
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Genetic variation in Charcot–Marie–Tooth genes contributes to sensitivity to paclitaxel-induced peripheral neuropathy
Published in Pharmacogenomics (01-08-2020)“…This study explored whether inherited variants in genes causing the hereditary neuropathy condition Charcot–Marie–Tooth disease are associated with sensitivity…”
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Patients carrying CYP2C83 have shorter systemic paclitaxel exposure
Published in Pharmacogenomics (01-01-2019)“…First, evaluate if patients carrying putatively diminished activity CYP2C8 genotype have longer paclitaxel exposure (e.g., time above threshold concentration…”
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11
Patients carrying
Published in Pharmacogenomics (01-12-2018)“…First, evaluate if patients carrying putatively diminished activity genotype have longer paclitaxel exposure (e.g., time above threshold concentration of 0.05…”
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2043
Published in Journal of clinical and translational science (01-09-2017)“…OBJECTIVES/SPECIFIC AIMS: Peripheral neuropathy is the dose limiting toxicity of paclitaxel treatment. Paclitaxel pharmacokinetics (PK), specifically the Cmax…”
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2043: Pharmacokinetic prediction of paclitaxel-induced peripheral neuropathy
Published in Journal of clinical and translational science (01-09-2017)“…OBJECTIVES/SPECIFIC AIMS: Peripheral neuropathy is the dose limiting toxicity of paclitaxel treatment. Paclitaxel pharmacokinetics (PK), specifically the Cmax…”
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