Search Results - "Vang Ørom, Ulf Andersson"
-
1
Predicting nuclear G-quadruplex RNA-binding proteins with roles in transcription and phase separation
Published in Nature communications (22-03-2024)“…RNA-binding proteins are central for many biological processes and their characterization has demonstrated a broad range of functions as well as a wide…”
Get full text
Journal Article -
2
Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin
Published in Nature communications (24-04-2018)“…Long ncRNAs are often enriched in the nucleus and at chromatin, but whether their dissociation from chromatin is important for their role in transcription…”
Get full text
Journal Article -
3
The Non-Coding RNA Journal Club: Highlights on Recent Papers-7
Published in Non-coding RNA (11-06-2019)“…We are delighted to share with you our seventh Journal Club and highlight some of the most interesting papers published recently [...]…”
Get full text
Journal Article -
4
N4-acetylcytidine (ac4C) promotes mRNA localization to stress granules
Published in EMBO reports (12-04-2024)“…Stress granules are an integral part of the stress response that are formed from non-translating mRNAs aggregated with proteins. While much is known about…”
Get full text
Journal Article -
5
Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington’s disease mice
Published in Cellular and molecular life sciences : CMLS (01-08-2022)“…N6-methyladenosine (m6A) regulates many aspects of RNA metabolism and is involved in learning and memory processes. Yet, the impact of a dysregulation of…”
Get full text
Journal Article -
6
m6A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts
Published in EMBO reports (11-10-2024)“…In Huntington’s disease (HD), aberrant processing of huntingtin ( HTT ) mRNA produces HTT1a transcripts that encode the pathogenic HTT exon 1 protein. The…”
Get full text
Journal Article -
7
Inhibiting Pri-miRNA Processing with Target Site Blockers
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2018)“…The pri-miRNA processing is important for the final regulatory role of miRNAs on the expression of their target transcripts. The processing variability between…”
Get more information
Journal Article -
8
Metabolic Pulse-Chase RNA Labeling for pri-miRNA Processing Dynamics
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2018)“…miRNA biogenesis is a multistep process starting with the cleavage of the primary miRNA transcript in the nucleus by the microprocessor complex. The pri-miRNA…”
Get more information
Journal Article -
9
Recent progress in miRNA biogenesis and decay
Published in RNA biology (2024)“…MicroRNAs are a class of small regulatory RNAs that mediate regulation of protein synthesis by recognizing sequence elements in mRNAs. MicroRNAs are processed…”
Get full text
Journal Article -
10
Transient N-6-Methyladenosine Transcriptome Sequencing Reveals a Regulatory Role of m6A in Splicing Efficiency
Published in Cell reports (Cambridge) (19-06-2018)“…Splicing efficiency varies among transcripts, and tight control of splicing kinetics is crucial for coordinated gene expression. N-6-methyladenosine (m6A) is…”
Get full text
Journal Article -
11
Targeting Polyadenylation for Retention of RNA at Chromatin
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…The various steps of RNA polymerase II transcription, including transcription initiation, splicing, and termination, are interlinked and tightly coordinated…”
Get more information
Journal Article -
12
m 6 A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts
Published in EMBO reports (11-10-2024)“…In Huntington's disease (HD), aberrant processing of huntingtin (HTT) mRNA produces HTT1a transcripts that encode the pathogenic HTT exon 1 protein. The…”
Get full text
Journal Article