Search Results - "Vang Ørom, Ulf Andersson"

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  1. 1

    Predicting nuclear G-quadruplex RNA-binding proteins with roles in transcription and phase separation by Luige, Johanna, Armaos, Alexandros, Tartaglia, Gian Gaetano, Ørom, Ulf Andersson Vang

    Published in Nature communications (22-03-2024)
    “…RNA-binding proteins are central for many biological processes and their characterization has demonstrated a broad range of functions as well as a wide…”
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    Journal Article
  2. 2

    Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin by Ntini, Evgenia, Louloupi, Annita, Liz, Julia, Muino, Jose M., Marsico, Annalisa, Ørom, Ulf Andersson Vang

    Published in Nature communications (24-04-2018)
    “…Long ncRNAs are often enriched in the nucleus and at chromatin, but whether their dissociation from chromatin is important for their role in transcription…”
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  3. 3
  4. 4

    N4-acetylcytidine (ac4C) promotes mRNA localization to stress granules by Kudrin, Pavel, Singh, Ankita, Meierhofer, David, Kuśnierczyk, Anna, Ørom, Ulf Andersson Vang

    Published in EMBO reports (12-04-2024)
    “…Stress granules are an integral part of the stress response that are formed from non-translating mRNAs aggregated with proteins. While much is known about…”
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  5. 5

    Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington’s disease mice by Pupak, Anika, Singh, Ankita, Sancho-Balsells, Anna, Alcalá-Vida, Rafael, Espina, Marc, Giralt, Albert, Martí, Eulàlia, Ørom, Ulf Andersson Vang, Ginés, Silvia, Brito, Verónica

    “…N6-methyladenosine (m6A) regulates many aspects of RNA metabolism and is involved in learning and memory processes. Yet, the impact of a dysregulation of…”
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  6. 6

    m6A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts by Pupak, Anika, Rodríguez-Navarro, Irene, Sathasivam, Kirupa, Singh, Ankita, Essmann, Amelie, del Toro, Daniel, Ginés, Silvia, Mouro Pinto, Ricardo, Bates, Gillian P, Vang Ørom, Ulf Andersson, Martí, Eulàlia, Brito, Verónica

    Published in EMBO reports (11-10-2024)
    “…In Huntington’s disease (HD), aberrant processing of huntingtin ( HTT ) mRNA produces HTT1a transcripts that encode the pathogenic HTT exon 1 protein. The…”
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    Journal Article
  7. 7

    Inhibiting Pri-miRNA Processing with Target Site Blockers by Louloupi, Annita, Ørom, Ulf Andersson Vang

    “…The pri-miRNA processing is important for the final regulatory role of miRNAs on the expression of their target transcripts. The processing variability between…”
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  8. 8

    Metabolic Pulse-Chase RNA Labeling for pri-miRNA Processing Dynamics by Louloupi, Annita, Ørom, Ulf Andersson Vang

    “…miRNA biogenesis is a multistep process starting with the cleavage of the primary miRNA transcript in the nucleus by the microprocessor complex. The pri-miRNA…”
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  9. 9

    Recent progress in miRNA biogenesis and decay by Bofill-De Ros, Xavier, Vang Ørom, Ulf Andersson

    Published in RNA biology (2024)
    “…MicroRNAs are a class of small regulatory RNAs that mediate regulation of protein synthesis by recognizing sequence elements in mRNAs. MicroRNAs are processed…”
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  10. 10

    Transient N-6-Methyladenosine Transcriptome Sequencing Reveals a Regulatory Role of m6A in Splicing Efficiency by Louloupi, Annita, Ntini, Evgenia, Conrad, Thomas, Ørom, Ulf Andersson Vang

    Published in Cell reports (Cambridge) (19-06-2018)
    “…Splicing efficiency varies among transcripts, and tight control of splicing kinetics is crucial for coordinated gene expression. N-6-methyladenosine (m6A) is…”
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  11. 11

    Targeting Polyadenylation for Retention of RNA at Chromatin by Ntini, Evgenia, Vang Ørom, Ulf Andersson

    “…The various steps of RNA polymerase II transcription, including transcription initiation, splicing, and termination, are interlinked and tightly coordinated…”
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  12. 12

    m 6 A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts by Pupak, Anika, Rodríguez-Navarro, Irene, Sathasivam, Kirupa, Singh, Ankita, Essmann, Amelie, Del Toro, Daniel, Ginés, Silvia, Mouro Pinto, Ricardo, Bates, Gillian P, Vang Ørom, Ulf Andersson, Martí, Eulàlia, Brito, Verónica

    Published in EMBO reports (11-10-2024)
    “…In Huntington's disease (HD), aberrant processing of huntingtin (HTT) mRNA produces HTT1a transcripts that encode the pathogenic HTT exon 1 protein. The…”
    Get full text
    Journal Article