Search Results - "Vaneev, Alexander N"
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Recent Advances in Nanopore Technology for Copper Detection and Their Potential Applications
Published in Nanomaterials (Basel, Switzerland) (08-05-2023)“…Recently, nanopore technology has emerged as a promising technique for the rapid, sensitive, and selective detection of various analytes. In particular, the…”
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Nano- and Microsensors for In Vivo Real-Time Electrochemical Analysis: Present and Future Perspectives
Published in Nanomaterials (Basel, Switzerland) (25-10-2022)“…Electrochemical nano- and microsensors have been a useful tool for measuring different analytes because of their small size, sensitivity, and favorable…”
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Sensing Cells-Peptide Hydrogel Interaction In Situ via Scanning Ion Conductance Microscopy
Published in Cells (Basel, Switzerland) (19-12-2022)“…Peptide-based hydrogels were shown to serve as good matrices for 3D cell culture and to be applied in the field of regenerative medicine. The study of the…”
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ROS Production by a Single Neutrophil Cell and Neutrophil Population upon Bacterial Stimulation
Published in Biomedicines (04-05-2023)“…The reactive oxygen species (ROS) production by a single neutrophil after stimulation with and was estimated by an electrochemical amperometric method with a…”
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Superoxide Dismutase 1 Nanoparticles (Nano-SOD1) as a Potential Drug for the Treatment of Inflammatory Eye Diseases
Published in Biomedicines (07-04-2021)“…Inflammatory eye diseases remain the most common clinical problem in ophthalmology. The secondary processes associated with inflammation, such as…”
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In Vitro and In Vivo Electrochemical Measurement of Reactive Oxygen Species After Treatment with Anticancer Drugs
Published in Analytical chemistry (Washington) (16-06-2020)“…monitoring of reactive oxygen species (ROS) in tumors during treatment with anticancer therapy is important for understanding the mechanism of action and in…”
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Electrochemical Nanopipette Sensor for In Vitro/In Vivo Detection of Cu2+ Ions
Published in Analytical chemistry (Washington) (09-01-2024)“…In vitro/in vivo detection of copper ions is a challenging task but one which is important in the development of new approaches to the diagnosis and treatment…”
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In Vitro/In Vivo Electrochemical Detection of Pt(II) Species
Published in Analytical chemistry (Washington) (29-03-2022)“…The biodistribution of chemotherapy compounds within tumor tissue is one of the main challenges in the development of antineoplastic drugs, and techniques for…”
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Electrochemical Detection of a Novel Pt(IV) Prodrug with the Metronidazole Axial Ligand in the Hypoxic Area
Published in Inorganic chemistry (19-09-2022)“…We report herein a Pt(IV) prodrug with metronidazole in axial positions Pt-Mnz. The nitroaromatic axial ligand was conjugated with a cisplatin scaffold to…”
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Electrochemical Nanopipette Sensor for In Vitro/In Vivo Detection of Cu 2+ Ions
Published in Analytical chemistry (Washington) (09-01-2024)“…In vitro/in vivo detection of copper ions is a challenging task but one which is important in the development of new approaches to the diagnosis and treatment…”
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Photoinduced Reduction of Novel Dual-Action Riboplatin Pt(IV) Prodrug
Published in ACS applied materials & interfaces (15-03-2023)“…Controlled photoreduction of Pt(IV) prodrugs is a challenging task due to the possibility of targeted light-controlled activation of anticancer agents without…”
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Changes in ROS/RNS Levels in Endothelial Cells in Experimental Bacteremia
Published in Chembiochem : a European journal of chemical biology (16-09-2024)“…A high‐precision system was developed for the quantification of biological analytes in single cells (reactive oxygen species (ROS) and reactive nitrogen…”
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PSMA-targeted small-molecule docetaxel conjugate: Synthesis and preclinical evaluation
Published in European journal of medicinal chemistry (05-01-2022)“…Prostate cancer is one of the most commonly diagnosed men's cancers and remains one of the leading causes of cancer death. The development of approaches to the…”
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Variation in tumor pH affects pH-triggered delivery of peptide-modified magnetic nanoparticles
Published in Nanomedicine (01-02-2021)“…Acidification of the extracellular matrix, an intrinsic characteristic of many solid tumors, is widely exploited for physiologically triggered delivery of…”
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New Small-Molecule Glycoconjugates of Docetaxel and GalNAc for Targeted Delivery to Hepatocellular Carcinoma
Published in Molecular pharmaceutics (04-01-2021)“…In this work, we have developed covalent and low molecular weight docetaxel delivery systems based on conjugation with -acetyl-d-galactosamine and studied…”
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Discovery of Bivalent GalNAc-Conjugated Betulin as a Potent ASGPR-Directed Agent against Hepatocellular Carcinoma
Published in Bioconjugate chemistry (21-04-2021)“…Herein, we describe the design, synthesis, and biological evaluation of novel betulin and N-acetyl-d-galactosamine (GalNAc) glycoconjugates and suggest them as…”
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Synthesis and Preclinical Evaluation of Small-Molecule Prostate-Specific Membrane Antigen-Targeted Abiraterone Conjugate
Published in Molecules (Basel, Switzerland) (01-12-2022)“…Prostate cancer is the second most common type of cancer among men. The main method of its treatment is androgen deprivation therapy, which has a wide range of…”
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In vitro/In vivo oxygen electrochemical nanosensor for bioanalysis
Published in Journal of electroanalytical chemistry (Lausanne, Switzerland) (15-12-2024)“…[Display omitted] •Pt nanoelectrodes allow rapid detection of O2 in multicellular MCF-7 spheroids and rat brain in vivo.•Oxygen profiles in MCF-7 spheroids…”
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Pt(IV) Prodrugs with Non-Steroidal Anti-inflammatory Drugs in the Axial Position
Published in Journal of medicinal chemistry (23-06-2022)“…We report herein the design, synthesis, and biological investigation of a series of novel Pt(IV) prodrugs with non-steroidal anti-inflammatory drugs naproxen,…”
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Novel Copper-Containing Cytotoxic Agents Based on 2‑Thioxoimidazolones
Published in Journal of medicinal chemistry (12-11-2020)“…A series of 73 ligands and 73 of their Cu+2 and Cu+1 copper complexes with different geometries, oxidation states of the metal, and redox activities were…”
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