Search Results - "Vanecková, Manuela"

Neurofilament levels are associated with blood–brain barrier integrity, lymphocyte extravasation, and risk factors following the first demyelinating event in multiple sclerosis by Uher, Tomas, McComb, Mason, Galkin, Shery, Srpova, Barbora, Oechtering, Johanna, Barro, Christian, Tyblova, Michaela, Bergsland, Niels, Krasensky, Jan, Dwyer, Michael, Havrdova, Eva Kubala, Posova, Helena, Vaneckova, Manuela, Zivadinov, Robert, Horakova, Dana, Kuhle, Jens, Ramanathan, Murali

“…Background: Increased blood brain barrier (BBB) permeability, CNS inflammation and neuroaxonal damage are pathological hallmarks in early multiple sclerosis…”
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Volumetric MRI markers and predictors of disease activity in early multiple sclerosis: a longitudinal cohort study by Kalincik, Tomas, Vaneckova, Manuela, Tyblova, Michaela, Krasensky, Jan, Seidl, Zdenek, Havrdova, Eva, Horakova, Dana

“…To compare clinical and MRI parameters between patients with clinically isolated syndrome and those converting to clinically definite multiple sclerosis within…”
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Serum lipid profile changes predict neurodegeneration in interferon-β1a-treated multiple sclerosis patients by Uher, Tomas, Fellows, Kelly, Horakova, Dana, Zivadinov, Robert, Vaneckova, Manuela, Sobisek, Lukas, Tyblova, Michaela, Seidl, Zdenek, Krasensky, Jan, Bergsland, Niels, Weinstock-Guttman, Bianca, Havrdova, Eva, Ramanathan, Murali

“…The purpose of this work was to determine whether changes in cholesterol profiles after interferon-β (IFN-β)1a treatment initiation following the first…”
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Serum neurofilament light chain reflects inflammation-driven neurodegeneration and predicts delayed brain volume loss in early stage of multiple sclerosis by Srpova, Barbora, Uher, Tomas, Hrnciarova, Tereza, Barro, Christian, Andelova, Michaela, Michalak, Zuzanna, Vaneckova, Manuela, Krasensky, Jan, Noskova, Libuse, Havrdova, Eva Kubala, Kuhle, Jens, Horakova, Dana

“…Background: Serum neurofilament light chain (sNfL) is a marker of neuroaxonal injury. There is a lack of studies investigating the dynamics of relationships…”
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Pontocerebellar atrophy is the hallmark neuroradiological finding in late-onset Tay-Sachs disease by Májovská, Jitka, Hennig, Anita, Nestrasil, Igor, Schneider, Susanne A., Jahnová, Helena, Vaněčková, Manuela, Magner, Martin, Dušek, Petr

“…Purpose Late-onset Tay-Sachs disease (LOTS) is a form of GM2 gangliosidosis, an autosomal recessive neurodegenerative disorder characterized by slowly…”
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Measurement of neurofilaments improves stratification of future disease activity in early multiple sclerosis by Uher, Tomas, Havrdova, Eva Kubala, Benkert, Pascal, Bergsland, Niels, Krasensky, Jan, Srpova, Barbora, Dwyer, Michael, Tyblova, Michaela, Meier, Stephanie, Vaneckova, Manuela, Horakova, Dana, Zivadinov, Robert, Leppert, David, Kalincik, Tomas, Kuhle, Jens

“…Background: The added value of neurofilament light chain levels in serum (sNfL) to the concept of no evidence of disease activity-3 (NEDA-3) has not yet been…”
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Anterior hippocampus volume loss in narcolepsy with cataplexy by Křečková, Martina, Kemlink, David, Šonka, Karel, Krásenský, Jan, Bušková, Jitka, Vaněčková, Manuela, Němcová, Veronika

“…Narcolepsy with cataplexy is a lifelong disease resulting from the loss of hypocretin neurons in the hypothalamus; structural changes are not, however, limited…”
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Pathological cut-offs of global and regional brain volume loss in multiple sclerosis by Uher, Tomas, Vaneckova, Manuela, Krasensky, Jan, Sobisek, Lukas, Tyblova, Michaela, Volna, Jana, Seidl, Zdenek, Bergsland, Niels, Dwyer, Michael G, Zivadinov, Robert, De Stefano, Nicola, Sormani, Maria Pia, Havrdova, Eva Kubala, Horakova, Dana

“…Background: Volumetric MRI surrogate markers of disease progression are lacking. Objective: To establish cut-off values of brain volume loss able to…”
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CSF Markers of Oxidative Stress Are Associated with Brain Atrophy and Iron Accumulation in a 2-Year Longitudinal Cohort of Early MS by Burgetova, Andrea, Dusek, Petr, Uher, Tomas, Vaneckova, Manuela, Vejrazka, Martin, Burgetova, Romana, Horakova, Dana, Srpova, Barbora, Kalousova, Marta, Noskova, Libuse, Levova, Katerina, Krasensky, Jan, Lambert, Lukas

“…In this prospective longitudinal study, we quantified regional brain volume and susceptibility changes during the first two years after the diagnosis of…”
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The clinical and paraclinical correlates of employment status in multiple sclerosis by Srpova, Barbora, Sobisek, Lukas, Novotna, Klara, Uher, Tomas, Friedova, Lucie, Vaneckova, Manuela, Krasensky, Jan, Kubala Havrdova, Eva, Horakova, Dana

“…Purpose To identify the clinical and paraclinical markers of employment status in multiple sclerosis (MS). Methods This was a cross-sectional sub-study…”
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Acute Methanol Poisoning: Prevalence and Predisposing Factors of Haemorrhagic and Non‐Haemorrhagic Brain Lesions by Zakharov, Sergey, Kotikova, Katerina, Vaneckova, Manuela, Seidl, Zdenek, Nurieva, Olga, Navratil, Tomas, Caganova, Blazena, Pelclova, Daniela

“…The purpose was to study the prevalence and predisposing factors of brain lesions in survivors of acute methanol poisoning. Clinical data on 106 patients with…”
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Diagnostic delay of multiple sclerosis: prevalence, determinants and consequences by Uher, Tomas, Adzima, Adrian, Srpova, Barbora, Noskova, Libuse, Maréchal, Bénédicte, Maceski, Aleksandra Maleska, Krasensky, Jan, Stastna, Dominika, Andelova, Michaela, Novotna, Klara, Vodehnalova, Karolina, Motyl, Jiri, Friedova, Lucie, Lindner, Jiri, Ravano, Veronica, Burgetova, Andrea, Dusek, Petr, Fialova, Lenka, Havrdova, Eva Kubala, Horakova, Dana, Kober, Tobias, Kuhle, Jens, Vaneckova, Manuela

“…Background: Early diagnosis and treatment of patients with multiple sclerosis (MS) are associated with better outcomes; however, diagnostic delays remain a…”
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Protective associations of HDL with blood-brain barrier injury in multiple sclerosis patients by Fellows, Kelly, Uher, Tomas, Browne, Richard W., Weinstock-Guttman, Bianca, Horakova, Dana, Posova, Helena, Vaneckova, Manuela, Seidl, Zdenek, Krasensky, Jan, Tyblova, Michaela, Havrdova, Eva, Zivadinov, Robert, Ramanathan, Murali

“…The purpose of this work was to investigate the associations of serum cholesterol and apolipoproteins with measures of blood-brain barrier (BBB) permeability…”
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Multisystem mitochondrial diseases due to mutations in mtDNA-encoded subunits of complex I by Danhelovska, Tereza, Kolarova, Hana, Zeman, Jiri, Hansikova, Hana, Vaneckova, Manuela, Lambert, Lukas, Kucerova-Vidrova, Vendula, Berankova, Kamila, Honzik, Tomas, Tesarova, Marketa

“…Maternally inherited complex I deficiencies due to mutations in MT-ND genes represent a heterogeneous group of multisystem mitochondrial disorders (MD) with a…”
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Gray matter atrophy patterns in multiple sclerosis: A 10-year source-based morphometry study by Bergsland, Niels, Horakova, Dana, Dwyer, Michael G., Uher, Tomas, Vaneckova, Manuela, Tyblova, Michaela, Seidl, Zdenek, Krasensky, Jan, Havrdova, Eva, Zivadinov, Robert

“…To investigate spatial patterns of gray matter (GM) atrophy and their association with disability progression in patients with early relapsing-remitting…”
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Neurological software tool for reliable atrophy measurement (NeuroSTREAM) of the lateral ventricles on clinical-quality T2-FLAIR MRI scans in multiple sclerosis by Dwyer, Michael G, Silva, Diego, Bergsland, Niels, Horakova, Dana, Ramasamy, Deepa, Durfee, Jaqueline, Vaneckova, Manuela, Havrdova, Eva, Zivadinov, Robert

“…There is a need for a brain volume measure applicable to the clinical routine scans. Nearly every multiple sclerosis (MS) protocol includes low-resolution 2D…”
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Periventricular gradient of T1 tissue alterations in multiple sclerosis by Vaneckova, Manuela, Piredda, Gian Franco, Andelova, Michaela, Krasensky, Jan, Uher, Tomas, Srpova, Barbora, Havrdova, Eva Kubala, Vodehnalova, Karolina, Horakova, Dana, Hilbert, Tom, Maréchal, Bénédicte, Fartaria, Mário João, Ravano, Veronica, Kober, Tobias

“…[Display omitted] •T1 relaxation times alterations were assessed based on a study-specific atlas.•T1 alterations depend on distance from lateral ventricles…”
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Lipid measures are associated with cognitive functioning in multiple sclerosis patients by Lőrincz, Balázs, Motýl, Jiří, Friedová, Lucie, Hrych, Daniel, Kubala Havrdová, Eva, Krásenský, Jan, Urban, Tadeáš, Kober, Tobias, Maréchal, Bénédicte, Vaněčková, Manuela, Horákova, Dana, Vrablik, Michal, Uher, Tomáš

“…•Growing evidence links dyslipidemia to cognitive outcomes in MS patients.•Study analyzed 211 MS patients with 361 timepoints over 15 years.•Elevated LDL-C…”
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Environmental factors associated with disease progression after the first demyelinating event: results from the multi-center SET study by Horakova, Dana, Zivadinov, Robert, Weinstock-Guttman, Bianca, Havrdova, Eva, Qu, Jun, Tamaño-Blanco, Miriam, Badgett, Darlene, Tyblova, Michaela, Bergsland, Niels, Hussein, Sara, Willis, Laura, Krasensky, Jan, Vaneckova, Manuela, Seidl, Zdenek, Lelkova, Petra, Dwyer, Michael G, Zhang, Ming, Yu, Haoying, Duan, Xiaotao, Kalincik, Tomas, Ramanathan, Murali

“…To investigate the associations of environmental MS risk factors with clinical and MRI measures of progression in high-risk clinically isolated syndromes (CIS)…”
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Gait and Balance Impairment after Acute Methanol Poisoning by Peterová, Kamila, Brožová, Hana, Klempíř, Jiří, Lišková, Irena, Bezdicek, Ondřej, Ridzoň, Petr, Vaněčková, Manuela, Zakharov, Sergej, Pelclová, Daniela, Miovský, Michal, Růžička, Evžen

“…Neurological sequelae including gait impairment were reported in survivors after methanol intoxication; however, no systematic study has been published so far…”
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