Search Results - "Vane, JR"

Selectivity of Nonsteroidal Antiinflammatory Drugs as Inhibitors of Constitutive and Inducible Cyclooxygenase by Mitchell, Jane A., Akarasereenont, Pravit, Thiemermann, Christoph, Flower, Roderick J., Vane, John R.

“…Constitutive cyclooxygenase (COX-1; prostaglandin-endoperoxide synthase, EC 1.14.99.1) is present in cells under physiological conditions, whereas COX-2 is…”
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Nomenclature for COX-2 Inhibitors by Vane, JR, Warner, TD

“…Patrignani and colleagues' human in-vitro wholeblood assay5 has become an accepted and reproducible standard for measuring the effects of anti-inflammatory…”
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NSAIDs, Cox-2 inhibitors, and the gut by Vane, J R

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The Croonian Lecture, 1993: The Endothelium: Maestro of the Blood Circulation by Vane, J. R.

“…The vascular endothelium plays a vital role in the control of the circulation. It metabolizes various vasoactive substances, coverts angiotensin I to…”
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Lipocortin 1 Mediates the Inhibition by Dexamethasone of the Induction by Endotoxin of Nitric Oxide Synthase in the Rat by Wu, Chin-Chen, Croxtall, Jamie D., Perretti, Mauro, Bryant, Clare E., Thiemermann, Christoph, Flower, Roderick J., Vane, John R.

“…Administration of Escherichia coli lipopolysaccharide (LPS; 10 mg/kg i.v.) to male Wistar rats caused within 240 min (i) a sustained fall (≈30 mmHg) in mean…”
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Platelet-Activating Factor Contributes to the Induction of Nitric Oxide Synthase by Bacterial Lipopolysaccharide by Szabó, Csaba, Wu, Chin-Chen, Mitchell, Jane A, Gross, Steven S, Thiemermann, Christoph, Vane, John R

“…This study investigates the role of endogenous platelet-activating factor (PAF) in the production of nitric oxide (NO) by constitutive and inducible isoforms…”
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Mediators Produced by the Endothelial Cell by GRYGLEWSKI, RYSZARD J, BOTTING, REGINA M, VANE, JOHN R

“…This review discusses the role of three mediators, synthesized by vascular endotheiial cells, that help to keep the surface of the normal endotheliuin…”
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A sensitive method for the assay of 5‐hydroxytryptamine by Vane, J.R., Vane, J.R.

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The use of isolated organs for detecting active substances in the circulating blood by Vane, J.R.

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Prostaglandins and the mechanism of analgesia produced by aspirin‐like drugs by Ferreira, S.H., Moncada, S., Vane, J.R.

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Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat by Ruetten, H, Thiemermann, C, Vane, JR

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Some recent advances in leukotriene research by Samuelsson, B

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Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat: Br J Pharmacol 1996; 118/1: 198–204 by Ruetten, H, Thiemermann, C, Vane, JR

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The technique of superfusion by Gaddum, J.H., Vane, J.R.

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PROSTACYCLIN (PGI2) INHIBITS THE FORMATION OF PLATELET THROMBI IN ARTERIOLES AND VENULES OF THE HAMSTER CHEEK POUCH by HIGGS, E.A., HIGGS, G.A., MONCADA, S., VANE, J.R.

“…1 Isolated rings of hamster aorta produced an unstable substance which inhibited platelet aggregation in vitro and had the same characteristics as…”
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Prostacyclin (PGI2) inhibits the formation of platelet thrombi in arterioles and venules of the hamster cheek pouch by Higgs, E.A., Higgs, G.A., Moncada, S., Vane, J.R.

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Avenoleic acid: a new oxylipin from oat seeds by Hamberg, M

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Human beta-trace in normal and pathological CNS tissues, genital organs and body fluids by Olsson, J E

“…The function of BTP is still unknown. In CNS, the high amount of BTP in the white CNS matter and the glial cells as well as in genital organs of the stroma of…”
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Prolongation of fibrinolytic activity of tissue plasminogen activator by nitrovasodilators by Korbut, R, Lidbury, P S, Vane, J R

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Catalytic and spectroscopic properties of linoleate diol synthase of the fungus Gaümannomyces graminis by Oliw, E H, Su, C

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