Search Results - "Vandervoort, K"

Early combined immunosuppression for the management of Crohn's disease (REACT): a cluster randomised controlled trial by Khanna, Reena, MD, Bressler, Brian, Prof, Levesque, Barrett G, MD, Zou, Guangyong, Prof, Stitt, Larry W, MSc, Greenberg, Gordon R, Prof, Panaccione, Remo, Prof, Bitton, Alain, Prof, Paré, Pierre, Prof, Vermeire, Séverine, Prof, D'Haens, Geert, Prof, MacIntosh, Donald, Prof, Sandborn, William J, Prof, Donner, Allan, Prof, Vandervoort, Margaret K, MSc, Morris, Joan C, MHSc, Feagan, Brian G, Prof

“…Summary Background Conventional management of Crohn's disease features incremental use of therapies. However, early combined immunosuppression (ECI), with a…”
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Development of interim patient‐reported outcome measures for the assessment of ulcerative colitis disease activity in clinical trials by Jairath, V., Khanna, R., Zou, G. Y., Stitt, L., Mosli, M., Vandervoort, M. K., D'Haens, G., Sandborn, W. J., Feagan, B. G., Levesque, B. G.

“…Summary Background Patient‐reported outcomes (PROs) have an increasingly important role in the evaluation of new therapies for inflammatory bowel disease. The…”
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A retrospective analysis: the development of patient reported outcome measures for the assessment of Crohn's disease activity by Khanna, R., Zou, G., D'Haens, G., Feagan, B. G., Sandborn, W. J., Vandervoort, M. K., Rolleri, R. L., Bortey, E., Paterson, C., Forbes, W. P., Levesque, B. G.

“…Summary Background The Crohn's Disease Activity Index (CDAI) is a measure of disease activity based on symptoms, signs and a laboratory test. The US Food and…”
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A Randomized, Double-Blind, Sham-Controlled Study of Granulocyte/Monocyte Apheresis for Active Ulcerative Colitis by Sands, Bruce E, Sandborn, William J, Feagan, Brian, Löfberg, Robert, Hibi, Toshifumi, Wang, Tao, Gustofson, Lisa–Marie, Wong, Cindy J, Vandervoort, Margaret K, Hanauer, Stephen

“…Background & Aims: Activated granulocytes and monocytes/macrophages are implicated in the pathogenesis of ulcerative colitis. Open-label studies and clinical…”
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Reproducibility of histological assessments of disease activity in UC by Mosli, Mahmoud H, Feagan, Brian G, Zou, Guangyong, Sandborn, William J, D'Haens, Geert, Khanna, Reena, Behling, Cynthia, Kaplan, Keith, Driman, David K, Shackelton, Lisa M, Baker, Kenneth A, MacDonald, John K, Vandervoort, Margaret K, Samaan, Mark A, Geboes, Karel, Valasek, Mark A, Pai, Rish, Langner, Cord, Riddell, Robert, Harpaz, Noam, Sewitch, Maida, Peterson, Michael, Stitt, Larry W, Levesque, Barrett G

“…Histopathology is potentially an important outcome measure in UC. Multiple histological disease activity (HA) indices, including the Geboes score (GS) and…”
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Methotrexate in Combination With Infliximab Is No More Effective Than Infliximab Alone in Patients With Crohn's Disease by Feagan, Brian G, McDonald, John W.D, Panaccione, Remo, Enns, Robert A, Bernstein, Charles N, Ponich, Terry P, Bourdages, Raymond, MacIntosh, Donald G, Dallaire, Chrystian, Cohen, Albert, Fedorak, Richard N, Paré, Pierre, Bitton, Alain, Saibil, Fred, Anderson, Frank, Donner, Allan, Wong, Cindy J, Zou, Guangyong, Vandervoort, Margaret K, Hopkins, Marybeth, Greenberg, Gordon R

“…Background & Aims Methotrexate and infliximab are effective therapies for Crohn's disease (CD). In the combination of maintenance methotrexate-infliximab…”
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A Controlled Trial of a Critical Pathway for Treatment of Community-Acquired Pneumonia by Marrie, Thomas J, Lau, Catherine Y, Wheeler, Susan L, Wong, Cindy J, Vandervoort, Margaret K, Feagan, Brian G, for the CAPITAL Study Investigators

“…CONTEXT Large variations exist among hospitals in the use of treatment resources for community-acquired pneumonia (CAP). Lack of a common approach to the…”
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Plasma-exchange therapy in chronic inflammatory demyelinating polyneuropathy : A double-blind, sham-controlled, cross-over study by HAHN, A. F, BOLTON, C. F, PILLAY, N, CHALK, C, BENSTEAD, T, BRIL, V, SHUMAK, K, VANDERVOORT, M. K, FEASBY, T. E

“…Eighteen patients with definite, untreated chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) of chronic progressive (nine patients) or relapsing…”
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Development and validation of a histological index for UC by Mosli, Mahmoud H, Feagan, Brian G, Zou, Guangyong, Sandborn, William J, D'Haens, Geert, Khanna, Reena, Shackelton, Lisa M, Walker, Christopher W, Nelson, Sigrid, Vandervoort, Margaret K, Frisbie, Valerie, Samaan, Mark A, Jairath, Vipul, Driman, David K, Geboes, Karel, Valasek, Mark A, Pai, Rish K, Lauwers, Gregory Y, Riddell, Robert, Stitt, Larry W, Levesque, Barrett G

“…Although the Geboes score (GS) and modified Riley score (MRS) are commonly used to evaluate histological disease activity in UC, their operating properties are…”
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Reliability among central readers in the evaluation of endoscopic findings from patients with Crohn's disease by Khanna, Reena, Zou, Guangyong, D'Haens, Geert, Rutgeerts, Paul, McDonald, J W D, Daperno, Marco, Feagan, Brian G, Sandborn, William J, Dubcenco, Elena, Stitt, Larry, Vandervoort, Margaret K, Donner, Allan, Luo, Allison, Levesque, Barrett G

“…The Crohn's Disease Endoscopic Index of Severity (CDEIS) and Simple Endoscopic Score for Crohn's Disease (SES-CD) are commonly used to assess Crohn's disease…”
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Histologic evaluation of ulcerative colitis: a systematic review of disease activity indices by Mosli, Mahmoud H, Feagan, Brian G, Sandborn, William J, Dʼhaens, Geert, Behling, Cynthia, Kaplan, Keith, Driman, David K, Shackelton, Lisa M, Baker, Kenneth A, Macdonald, John K, Vandervoort, Margaret K, Geboes, Karel, Levesque, Barrett G

“…Ulcerative colitis (UC) is an idiopathic inflammatory disorder. Currently, the main goals of treatment are to induce and maintain clinical and/or endoscopic…”
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Treatment of Ulcerative Colitis with a Humanized Antibody to the α4β7 Integrin by Feagan, Brian G, Greenberg, Gordon R, Wild, Gary, Fedorak, Richard N, Paré, Pierre, McDonald, John W.D, Dubé, Rejean, Cohen, Albert, Steinhart, A. Hillary, Landau, Steven, Aguzzi, Rasha A, Fox, Irving H, Vandervoort, Margaret K

“…In this six-week randomized trial of MLN02 — a humanized antibody to the α 4 β 7 integrin — in patients with ulcerative colitis, MLN02 was associated with…”
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A Simplified Approach to the Treatment of Uncomplicated Hypertension: A Cluster Randomized, Controlled Trial by Feldman, Ross D, Zou, Guang Y, Vandervoort, Margaret K, Wong, Cindy J, Nelson, Sigrid A.E, Feagan, Brian G

“…Notwithstanding the availability of antihypertensive drugs and practice guidelines, blood pressure control remains suboptimal. The complexity of current…”
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The development of a magnetic resonance imaging index for fistulising Crohn's disease by Samaan, M. A., Puylaert, C. A. J., Levesque, B. G., Zou, G. Y., Stitt, L., Taylor, S. A., Shackelton, L. M., Vandervoort, M. K., Khanna, R., Santillan, C., Rimola, J., Hindryckx, P., Nio, C. Y., Sandborn, W. J., D'Haens, G., Feagan, B. G., Jairath, V., Stoker, J.

“…Summary Background Magnetic resonance imaging (MRI) is the gold standard for assessment of perianal fistulising Crohn's disease (CD). The Van Assche index is…”
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Treatment of Active Crohn's Disease With MLN0002, a Humanized Antibody to the α4β7 Integrin by Feagan, Brian G, Greenberg, Gordon R, Wild, Gary, Fedorak, Richard N, Paré, Pierre, McDonald, John W.D, Cohen, Albert, Bitton, Alain, Baker, Jeffrey, Dubé, Réjean, Landau, Steven B, Vandervoort, Margaret K, Parikh, Asit

“…Background & Aims Selective blockade of lymphocyte–vascular endothelium interactions in the gastrointestinal tract is a promising therapeutic strategy for…”
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Treatment and outcomes of community-acquired pneumonia at Canadian hospitals by Feagan, B G, Marrie, T J, Lau, C Y, Wheeler, S L, Wong, C J, Vandervoort, M K

“…Community-acquired pneumonia is a common disease with a large economic burden. We assessed clinical practices and outcomes among patients with…”
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A new ambient-pressure organic superconductor, .kappa.-(ET)2Cu[N(CN)2]Br, with the highest transition temperature yet observed (inductive onset Tc = 11.6 K, resistive onset = 12.5 K) by Kini, Aravinda M, Geiser, Urs, Wang, Hau H, Carlson, K. Douglas, Williams, Jack M, Kwok, W. K, Vandervoort, K. G, Thompson, James E, Stupka, Daniel L

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X-ray reflectivity and scanning-tunneling-microscope study of kinetic roughening of sputter-deposited gold films during growth by YOU, H, CHIARELLO, R. P, KIM, H. K, VANDERVOORT, K. G

“…An [ital in] [ital situ] x-ray reflectivity study of the dynamic evolution of a growing interface was carried out for gold sputter-deposited onto a polished…”
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Omega-3 Free Fatty Acids for the Maintenance of Remission in Crohn Disease: The EPIC Randomized Controlled Trials by Feagan, Brian G, Sandborn, William J, Mittmann, Ulrich, Bar-Meir, Simon, D’Haens, Geert, Bradette, Marc, Cohen, Albert, Dallaire, Chrystian, Ponich, Terry P, McDonald, John W. D, Hébuterne, Xavier, Paré, Pierre, Klvana, Pavel, Niv, Yaron, Ardizzone, Sandro, Alexeeva, Olga, Rostom, Alaa, Kiudelis, Gediminas, Spleiss, Johannes, Gilgen, Denise, Vandervoort, Margaret K, Wong, Cindy J, Zou, Guang Yong, Donner, Allan, Rutgeerts, Paul

“…CONTEXT Maintenance therapy for Crohn disease features the use of immunosuppressive drugs, which are associated with an increased risk of infection…”
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Randomised non‐inferiority trial: 1600 mg versus 400 mg tablets of mesalazine for the treatment of mild‐to‐moderate ulcerative colitis by D'Haens, G. R., Sandborn, W. J., Zou, G., Stitt, L. W., Rutgeerts, P. J., Gilgen, D., Jairath, V., Hindryckx, P., Shackelton, L. M., Vandervoort, M. K., Parker, C. E., Muller, C., Pai, R. K., Levchenko, O., Marakhouski, Y., Horynski, M., Mikhailova, E., Kharchenko, N., Pimanov, S., Feagan, B. G.

“…Summary Background High concentration mesalazine formulations are more convenient than conventional low concentration formulations for the treatment of…”
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