Search Results - "Vanderschuren, Louk J.M.J"
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Putting a spin on the dorsal–ventral divide of the striatum
Published in Trends in neurosciences (Regular ed.) (01-08-2004)“…Since its conception three decades ago, the idea that the striatum consists of a dorsal sensorimotor part and a ventral portion processing limbic information…”
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Cannabinoid and opioid modulation of social play behavior in adolescent rats: Differential behavioral mechanisms
Published in European neuropsychopharmacology (01-07-2008)“…Abstract We have recently shown that the pharmacological mechanisms through which cannabinoid and opioid drugs influence social play behavior in adolescent…”
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Conditioned place preference induced by social play behavior: Parametrics, extinction, reinstatement and disruption by methylphenidate
Published in European neuropsychopharmacology (01-09-2009)“…Abstract In this study, we investigated behavioral factors underlying conditioned place preference (CPP) induced by social interaction in adolescent rats. We…”
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A cannabinoid mechanism in relapse to cocaine seeking
Published in Nature medicine (01-10-2001)“…Treatment of cocaine addiction is hampered by high rates of relapse even after prolonged drug abstinence. This relapse to compulsive cocaine use can be…”
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5
Glucocorticoid receptor antagonism disrupts the reconsolidation of social reward-related memories in rats
Published in Behavioural pharmacology (01-06-2014)“…Reconsolidation is the process whereby consolidated memories are destabilized upon retrieval and restabilized to persist for later use. Although the…”
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The neurobiology of social play and its rewarding value in rats
Published in Neuroscience and biobehavioral reviews (01-11-2016)“…•Social play behaviour is a highly rewarding social activity abundant in young animals.•Social play behaviour facilitates the development of brain and…”
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7
The neuropharmacology of impulsive behaviour
Published in Trends in pharmacological sciences (Regular ed.) (01-04-2008)“…Impulsivity is a heterogenous phenomenon encompassing several behavioural phenomena that can be dissociated neuroanatomically as well as pharmacologically…”
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The pleasures of play: pharmacological insights into social reward mechanisms
Published in Trends in pharmacological sciences (Regular ed.) (01-10-2010)“…Like human children, most young mammals devote a significant amount of time and energy playing together, and social play is fun. Although social play is very…”
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Modeling autism-relevant behavioral phenotypes in rats and mice: Do ‘autistic’ rodents exist?
Published in Behavioural pharmacology (01-09-2015)“…Autism spectrum disorders (ASD) are among the most severe developmental psychiatric disorders known today, characterized by impairments in communication and…”
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Evaluating the rewarding nature of social interactions in laboratory animals
Published in Developmental cognitive neuroscience (01-10-2011)“…Positive social interactions are essential for emotional well-being, healthy development, establishment and maintenance of adequate social structures and…”
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CaMKIIa+ neurons in the bed nucleus of the stria terminalis modulate pace of natural reward seeking depending on internal state
Published in Psychopharmacology (01-06-2024)“…This study aims to investigate the underlying neurobiological mechanisms that regulate natural reward seeking behaviors, specifically in the context of sexual…”
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Dissociable effects of monoamine reuptake inhibitors on distinct forms of impulsive behavior in rats
Published in Psychopharmacology (01-01-2012)“…Rationale High levels of impulsivity are a core symptom of psychiatric disorders such as ADHD, mania, personality disorders and drug addiction. The…”
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Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats
Published in The Journal of neuroscience (24-10-2012)“…The brain endocannabinoid system plays a crucial role in emotional processes. We have previously identified an important role for endocannabinoids in social…”
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14
Social play behavior, ultrasonic vocalizations and their modulation by morphine and amphetamine in Wistar and Sprague-Dawley rats
Published in Psychopharmacology (01-04-2014)“…Rationale Social play behavior is the most characteristic social behavior in young mammals. It is highly rewarding and crucial for proper neurobehavioral…”
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Distinct roles of the endocannabinoids anandamide and 2-arachidonoylglycerol in social behavior and emotionality at different developmental ages in rats
Published in European neuropsychopharmacology (01-08-2015)“…Abstract To date, our understanding of the relative contribution and potential overlapping roles of the endocannabinoids anandamide (AEA) and…”
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Simultaneous blockade of dopamine and noradrenaline reuptake promotes disadvantageous decision making in a rat gambling task
Published in Psychopharmacology (01-02-2013)“…Rationale The inability to make profitable long-term decisions has been implicated in several psychiatric disorders. There is emerging evidence to support a…”
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17
Drug Seeking Becomes Compulsive after Prolonged Cocaine Self-Administration
Published in Science (American Association for the Advancement of Science) (13-08-2004)“…Compulsive drug use in the face of adverse consequences is a hallmark feature of addiction, yet there is little preclinical evidence demonstrating the actual…”
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Strain- and context-dependent effects of the anandamide hydrolysis inhibitor URB597 on social behavior in rats
Published in European neuropsychopharmacology (01-08-2014)“…Abstract Genetic and environmental factors play an important role in the cannabinoid modulation of motivation and emotion. Therefore, the aim of the present…”
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Disrupted social development enhances the motivation for cocaine in rats
Published in Psychopharmacology (01-04-2014)“…Rationale Early social experiences are of major importance for behavioural development. In particular, social play behaviour during post-weaning development is…”
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Critical Involvement of Dopaminergic Neurotransmission in Impulsive Decision Making
Published in Biological psychiatry (1969) (01-07-2006)“…Impulsive decision making, apparent as intolerance for reinforcement delay, is prominent in attention-deficit/hyperactivity disorder. Commonly prescribed for…”
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