Search Results - "Vandermeulen, Matthew D"
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1
Gene by Environment Interactions reveal new regulatory aspects of signaling network plasticity
Published in PLoS genetics (04-01-2022)“…Phenotypes can change during exposure to different environments through the regulation of signaling pathways that operate in integrated networks. How signaling…”
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Journal Article -
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Ecological inducers of the yeast filamentous growth pathway reveal environment-dependent roles for pathway components
Published in mSphere (24-10-2023)“…Signaling modules, such as mitogen-activated protein kinase (MAPK) pathways, are evolutionarily conserved drivers of cell differentiation and stress responses…”
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Journal Article -
3
Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability
Published in eLife (02-06-2023)“…Degradation of most yeast mRNAs involves decapping by Dcp1/Dcp2. DEAD-box protein Dhh1 has been implicated as an activator of decapping, in coupling codon…”
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4
Conserved signaling modules regulate filamentous growth in fungi: a model for eukaryotic cell differentiation
Published in Genetics (Austin) (07-10-2024)“…Eukaryotic organisms are composed of different cell types with defined shapes and functions. Specific cell types are produced by the process of cell…”
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New Aspects of Invasive Growth Regulation Identified by Functional Profiling of MAPK Pathway Targets in Saccharomyces cerevisiae
Published in Genetics (Austin) (01-09-2020)“…Abstract MAPK pathways are universal regulators of morphogenesis and stress responses in eukaryotes. In this study, Vandermeulen and Cullen identified the…”
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Journal Article -
6
Turnover and Bypass of p21-Activated Kinase During Cdc42-Dependent MAPK Signaling in Yeast
Published in The Journal of biological chemistry (01-11-2023)“…Mitogen-activated protein kinase (MAPK) pathways regulate multiple cellular behaviors, including the response to stress and cell differentiation, and are…”
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Journal Article -
7
The Caenorhabditis elegans innexin INX-20 regulates nociceptive behavioral sensitivity
Published in Genetics (Austin) (06-04-2023)“…Abstract Organisms rely on chemical cues in their environment to indicate the presence or absence of food, reproductive partners, predators, or other harmful…”
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Journal Article -
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Gain- and loss-of-function alleles within signaling pathways lead to phenotypic diversity among individuals
Published in iScience (18-10-2024)“…Understanding how phenotypic diversity is generated is an important question in biology. We explored phenotypic diversity among wild yeast isolates…”
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Journal Article -
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New Aspects of Invasive Growth Regulation Identified by Functional Profiling of MAPK Pathway Targets in Saccharomyces cerevisiae
Published in Genetics (Austin) (01-09-2020)“…MAPK pathways are universal regulators of morphogenesis and stress responses in eukaryotes. In this study, Vandermeulen and Cullen identified the function of…”
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Journal Article -
10
The Examination of Signaling Pathway Gene by Environment Interactions in the Regulation of Filamentous Growth
Published 01-01-2022“…The major focus of this dissertation was to understand how exposing signaling pathways to different growth conditions (i.e. environments) can improve the way…”
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Dissertation