Search Results - "Vandermeers, Andre"
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Development of high affinity selective VIP1 receptor agonists
Published in Peptides (New York, N.Y. : 1980) (1997)“…The biological effects of VIP are mediated by at least two VIP receptors: the VIP1 and the VIP2 receptors that were cloned in rat, human and mice. As the mRNA…”
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Fragments of pituitary adenylate cyclase activating polypeptide discriminate between type I and II recombinant receptors
Published in European journal of pharmacology (04-12-1995)“…Pituitary adenylate cyclase activating polypeptide (PACAP) analogues were tested for their ability to occupy the recombinant selective PACAP receptors (PACAP…”
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The long-acting vasoactive intestinal polypeptide agonist RO 25-1553 is highly selective of the VIP2 receptor subclass
Published in Peptides (New York, N.Y. : 1980) (1997)“…RO 25-1553 is a synthetic VIP analogue that induced a long-lasting relaxation of tracheal and bronchial smooth muscles as well as a reduction of edema and…”
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Properties and distribution of receptors for pituitary adenylate cyclase activating peptide (PACAP) in rat brain and spinal cord
Published in Regulatory peptides (13-08-1991)“…A high density (in the pmol/mg protein range) of specific functional receptors for PACAP (pituitary adenylate cyclase activating polypeptide) was observed in…”
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Adenylate cyclase activation by VIP and PACAP in the retina and choroid: effects of antagonists
Published in Annals of the New York Academy of Sciences (26-12-1996)Get more information
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Calmodulin Activation of Adenylate Cyclase in Pancreatic Islets
Published in Science (American Association for the Advancement of Science) (12-10-1979)“…Pancreatic islets contain calmodulin. The protein binds to a particulate fraction derived from the islets and stimulates adenylate cyclase activity in this…”
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C-Terminally shortened pituitary adenylate cyclase-activating peptides (PACAP) discriminate PACAP I, PACAP II-VIP1 and PACAP II-VIP2 recombinant receptors
Published in Regulatory peptides (23-04-1996)“…Pituitary adenylate cyclase-activating polypeptide (PACAP) analogues were tested for their ability to occupy the recombinant selective PACAP receptors (PACAP…”
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The C-terminus ends of secretin and VIP interact with the N-terminal domains of their receptors
Published in Peptides (New York, N.Y. : 1980) (1996)“…C-terminally truncated secretin and VIP molecules were synthesized, and their ability to oocupy the recombinant secretin and VIP 1 receptors stably expressed…”
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Isolation and primary structure of rat secretin
Published in Biochemical and biophysical research communications (28-04-1989)“…A major form of rat secretin was purified to homogeneity from small intestine, being detected with a porcine secretin radioimmunoassay throughout 7…”
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Purification and amino acid sequence of motilin from cat small intestine
Published in Regulatory peptides (19-11-1993)“…Motilin was isolated from cat small intestine by a series of chromatographic steps. Using a radioreceptor assay, based upon binding of iodinated porcine…”
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Primary structure of helodermin, a VIP-secretin-like peptide isolated from Gila monster venom
Published in FEBS letters (10-12-1984)“…The complete amino acid sequence of helodermin isolated from the venom of Gila monster was elucidated. The peptide was shown to be a basic…”
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Variable distribution of three molecular forms of peptide histidine isoleucinamide in rat tissues: identification of the large molecular form as peptide histidine valine-(1-42)
Published in Endocrinology (Philadelphia) (01-11-1989)“…We previously isolated three forms of peptide histidine isoleucinamide (PHI) from rat small intestine by chromatography on Fractogel. Rat PHI-(1-27)-NH2 and…”
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Addition of the (28-38) peptide sequence of PACAP to the VIP sequence modifies peptide selectivity and efficacy
Published in International journal of peptide and protein research (01-10-1996)“…Chimeric peptides were synthesized by adding the C-terminal extension 28-38 of the pituitary adenylate cyclase activating polypeptide (PACAP) to the sequences…”
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Antagonistic properties are shifted back to agonistic properties by further N‐terminal shortening of pituitary adenylate‐cyclase‐activating peptides in human neuroblastoma NB‐OK‐1 cell membranes
Published in European journal of biochemistry (15-09-1992)“…N‐terminally shortened analogs of the 27‐amino‐acid and 38‐amino‐acid forms of the pituitaryadenylate‐cyclase‐activating neuropeptide, PACAP(1–27) and…”
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Development of High Affinity Selective VIP 1 Receptor Agonists
Published in Peptides (New York, N.Y. : 1980) (1997)“…Gourlet, P., A. Vandermeers, P. Vertongen, J. Rathe, P. De Neef, J. Cnudde, M. Waelbroeck and P. Robberecht. Development of high affinity selective VIP 1…”
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C-Terminally shortened pituitary adenylate cyclase-activating peptides (PACAP) discriminate PACAP I, PACAP II-VIP 1 and PACAP II-VIP 2 recombinant receptors
Published in Regulatory peptides (1996)“…Pituitary adenylate cyclase-activating polypeptide (PACAP) analogues were tested for their ability to occupy the recombinant selective PACAP receptors (PACAP…”
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Differences in primary structure among five phospholipases A2 from Heloderma suspectum
Published in European journal of biochemistry (28-03-1991)“…Five increasingly anionic phospholipases A2 (Pa1– Pa5) exist in the venom of the lizard Heloderma suspectum. We recently elucidated the sequence of Pa5, the…”
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Structural requirements for the occupancy of pituitary adenylate‐cyclase‐activating‐peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB‐OK‐1 cell membranes
Published in European journal of biochemistry (01-07-1992)“…In these structure activity studies, the 46 analogs of the 27‐amino‐acid form of the pituitary‐adenylate‐cyclase‐activating peptide, PACAP(1–27), and the…”
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Carica papaya latex is a rich source of a class II chitinase
Published in Phytochemistry (Oxford) (01-12-1997)“…This enzyme, purified to homogeneity, was classified on the basis of its N-terminal amino acid sequence, activity and free thiol functions content. Some…”
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