Search Results - "Vandergrift, William A."
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Deep learning applied to whole‐brain connectome to determine seizure control after epilepsy surgery
Published in Epilepsia (Copenhagen) (01-09-2018)“…Summary Objective We evaluated whether deep learning applied to whole‐brain presurgical structural connectomes could be used to predict postoperative seizure…”
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Intracranial Angiomatoid Fibrous Histiocytoma: a Case report and literature review
Published in World neurosurgery (01-12-2016)“…Abstract Background Angiomatoid fibrous histiocytoma (AFH) is a rare and low-grade soft tissue lesion that typically arises from subcutaneous and deep dermal…”
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3
Drug Resistance in Glioblastoma: A Mini Review
Published in Neurochemical research (01-06-2012)“…Glioblastoma multiforme (GBM) is recognized as the most common and lethal form of central nervous system cancer. Currently used surgical techniques,…”
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Cost-effectiveness of the endoscopic versus microscopic approach for pituitary adenoma resection
Published in The Laryngoscope (01-01-2015)“…Objectives/Hypothesis To evaluate the cost‐effectiveness of an endoscopic versus microscopic approach to pituitary adenoma resection. Study Design Markov…”
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In Vitro Effect of Dovitinib (TKI258), a Multi-Target Angiokinase Inhibitor on Aggressive Meningioma Cells
Published in Cancer investigation (02-07-2020)“…Background: Meningiomas represent ∼30% of primary central nervous system (CNS) tumors. Although advances in surgery and radiotherapy have significantly…”
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Preconditioning with INC280 and LDK378 drugs sensitizes MGMT-unmethylated glioblastoma to temozolomide: Pre-clinical assessment
Published in Journal of the neurological sciences (15-11-2020)“…Temozolomide (TMZ) therapy is the standard of care for patients with glioblastoma (GBM). Clinical studies have shown that elevated levels of DNA repair protein…”
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Mechanisms and clinical significance of histone deacetylase inhibitors: epigenetic glioblastoma therapy
Published in Anticancer research (01-02-2015)“…Glioblastoma is the most common and deadliest of malignant primary brain tumors (Grade IV astrocytoma) in adults. Current standard treatments have been…”
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Oncolytic myxoma virus synergizes with standard of care for treatment of glioblastoma multiforme
Published in Oncolytic virotherapy (01-01-2018)“…Glioblastoma multiforme (GBM) is an aggressive form of brain cancer which is associated with poor prognosis. A variety of oncolytic viruses have previously…”
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Single agent efficacy of the HDAC inhibitor DATS in preclinical models of glioblastoma
Published in Cancer chemotherapy and pharmacology (01-12-2018)“…Purpose/introduction Glioblastoma (GB) remains incurable despite aggressive chemotherapy, radiotherapy, and surgical interventions; immunotherapies remain…”
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A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway
Published in Tumor biology (01-09-2015)“…Recurrent meningiomas constitute an uncommon but significant problem after standard (surgery and radiation) therapy failure. Current chemotherapies…”
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Trigeminal Neuralgia Secondary to Meckel's Cave Meningoencephaloceles: A Systematic Review and Illustrative Case
Published in Neurology India (01-05-2022)“…Background: The culprit of trigeminal neuralgia (TGN) may occur at any point between the nerve's root entry zone (REZ) and Meckel's cave. Meckel's cave…”
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RIP1 and RIP3 complex regulates radiation-induced programmed necrosis in glioblastoma
Published in Tumor biology (01-06-2016)“…Radiation-induced necrosis (RN) is a relatively common side effect of radiation therapy for glioblastoma. However, the molecular mechanisms involved and the…”
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13
Temporal Lobe Epilepsy Surgical Outcomes Can Be Inferred Based on Structural Connectome Hubs: A Machine Learning Study
Published in Annals of neurology (01-11-2020)“…Objective Medial temporal lobe epilepsy (TLE) is the most common form of medication‐resistant focal epilepsy in adults. Despite removal of medial temporal…”
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Quantifying hubness to predict surgical outcomes in epilepsy: Assessing resection‐hub alignment in interictal intracranial EEG networks
Published in Epilepsia (Copenhagen) (01-11-2024)“…Objective Intracranial EEG can identify epilepsy‐related networks in patients with focal epilepsy; however, the association between network organization and…”
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Accounting for repeat intervention costs in the economic comparison of laser interstitial thermal therapy and anterior temporal lobectomy for treatment of refractory temporal lobe epilepsy
Published in Epilepsy & behavior (01-07-2024)“…•Failure to account for ATL following LITT provides an underestimate of costs.•LITT costs more if the ratio of subsequent ATLs exceeds the cost reduction of…”
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Metastatic Hepatocellular Carcinoma With Associated Spinal Cord Compression
Published in The American journal of the medical sciences (01-02-2011)“…Abstract Metastatic hepatocellular carcinoma is a rare occurrence in the United States. The prognosis is poor, with a survival time of months from the time of…”
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Vagus nerve stimulation paired with rehabilitation for stroke: Implantation experience from the VNS-REHAB trial
Published in Journal of clinical neuroscience (01-11-2022)“…•Vagus nerve stimulation (VNS) paired with rehabilitation has been demonstrated to be beneficial in a population of stroke patients.•Stroke patients have…”
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Malignant sarcomatous transformation of calvarial fibrous dysplasia: illustrative case
Published in Journal of neurosurgery. Case lessons (11-11-2024)“…BACKGROUND Fibrous dysplasia (FD) is a nonheritable genetic disorder characterized by abnormal osteogenesis, resulting in benign bone lesions in one or…”
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Vasospasm secondary to responsive neurostimulator placement: a previously unreported complication. Illustrative case
Published in Journal of neurosurgery. Case lessons (29-05-2023)“…The Responsive Neurostimulation (RNS) system is an implantable device for patients with drug-resistant epilepsy who are not candidates for resection of a…”
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Percutaneous ethanol embolization and cement augmentation of aggressive vertebral hemangiomas at two adjacent vertebral levels
Published in Journal of neuroradiology (01-10-2014)“…Summary This report describes a case of successful percutaneous direct-puncture ethanol embolization, followed by vertebroplasty, of an aggressive vertebral…”
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