Search Results - "Vandenboom, Rene"

Potentiation of force by extracellular potassium and posttetanic potentiation are additive in mouse fast-twitch muscle in vitro by Overgaard, Kristian, Gittings, William, Vandenboom, Rene

“…The influence of moderately elevated extracellular potassium concentration ([K + ]) on muscle force has marked similarities to that of posttetanic potentiation…”
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Myosin phosphorylation potentiates steady-state work output without altering contractile economy of mouse fast skeletal muscles by Gittings, William, Bunda, Jordan, Vandenboom, Rene

“…Skeletal myosin light chain kinase (skMLCK)-catalyzed phosphorylation of the myosin regulatory light chain (RLC) increases (i.e. potentiates) mechanical work…”
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Myosin phosphorylation improves contractile economy of mouse fast skeletal muscle during staircase potentiation by Bunda, Jordan, Gittings, William, Vandenboom, Rene

“…Phosphorylation of the myosin regulatory light chain (RLC) by skeletal myosin light chain kinase (skMLCK) potentiates rodent fast twitch muscle but is an…”
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Posttetanic potentiation improves neuromuscular efficiency of mouse muscle in vitro by Laidlaw, Ryan, Vandenboom, Rene

“…Neuromuscular efficiency is defined as the ratio of work output to stimulation rate. The purpose of these experiments was to test the hypothesis that…”
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Myosin light chain kinase and the role of myosin light chain phosphorylation in skeletal muscle by Stull, James T., Kamm, Kristine E., Vandenboom, Rene

“…► Ca 2+/calmodulin-dependent skMLCK phosphorylates RLC of sarcomeric myosin. ► SkMLCK is expressed specifically in skeletal muscle fibers. ► Combined…”
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Modulation of Skeletal Muscle Contraction by Myosin Phosphorylation by Vandenboom, Rene

“…The striated muscle sarcomere is a highly organized and complex enzymatic and structural organelle. Evolutionary pressures have played a vital role in…”
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Contraction-induced enhancement of relaxation during high force contractions of mouse lumbrical muscle at 37°C by Smith, Ian C, Vandenboom, Rene, Tupling, A Russell

“…Repeated stimulation of unfatigued rodent fast-twitch skeletal muscle accelerates the kinetics of tension relaxation through an unknown mechanism. This effect…”
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Myosin phosphorylation potentiated steady state work output without altering contractile economy of mouse fast skeletal muscles by Gittings, William, Bunda, Jordan, Vandenboom, Rene

“…Skeletal myosin light chain kinase (skMLCK) catalyzed phosphorylation of the myosin regulatory light chain (RLC) increases (i.e. potentiates) mechanical work…”
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GSK3 inhibition with low dose lithium supplementation augments murine muscle fatigue resistance and specific force production by Whitley, Kennedy C., Hamstra, Sophie I., Baranowski, Ryan W., Watson, Colton J. F., MacPherson, Rebecca E. K., MacNeil, Adam J., Roy, Brian D., Vandenboom, Rene, Fajardo, Val A.

“…Calcineurin is a Ca2+‐dependent serine/threonine phosphatase that dephosphorylates nuclear factor of activated T cells (NFAT), allowing for NFAT entry into the…”
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Tetanic force potentiation of mouse fast muscle is shortening speed dependent by Gittings, William, Huang, Jian, Vandenboom, Rene

“…The activity dependent potentiation of peak isometric force associated with phosphorylation of the myosin regulatory light chain (RLC) is generally restricted…”
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Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target by Baranowski, Ryan W., Braun, Jessica L., Hockey, Briana L., Yumol, Jenalyn L., Geromella, Mia S., Watson, Colton J.F., Kurgan, Nigel, Messner, Holt N., Whitley, Kennedy C., MacNeil, Adam J., Gauquelin-Koch, Guillemette, Bertile, Fabrice, Gittings, William, Vandenboom, Rene, Ward, Wendy E., Fajardo, Val A.

“…We examined the effects of ∼30 days of spaceflight on glycogen synthase kinase 3 (GSK3) content and inhibitory serine phosphorylation in murine muscle and bone…”
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effect of skeletal myosin light chain kinase gene ablation on the fatigability of mouse fast muscle by Gittings, William, Huang, Jiang, Smith, Ian C, Quadrilatero, Joe, Vandenboom, Rene

“…Contraction-induced activation of a skeletal muscle specific Ca²⁺ and calmodulin dependent myosin light chain kinase (skMLCK) catalyzes phosphorylation of the…”
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PDH activation during in vitro muscle contractions in PDH kinase 2 knockout mice: effect of PDH kinase 1 compensation by Dunford, Emily C, Herbst, Eric A, Jeoung, Nam Ho, Gittings, William, Inglis, J Greig, Vandenboom, Rene, LeBlanc, Paul J, Harris, Robert A, Peters, Sandra J

“…Pyruvate dehydrogenase (PDH) plays an important role in regulating carbohydrate oxidation in skeletal muscle. PDH is deactivated by a set of PDH kinases (PDK1,…”
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The effect of muscle length on post-tetanic potentiation of C57BL/6 and skMLCK−/− mouse EDL muscles by Angelidis, Angelos, Vandenboom, Rene

“…Post-tetanic potentiation of fast-twitch skeletal muscle is dependent on muscle length, with greater potentiation observed at shorter compared to longer…”
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Mechanisms of Estrogen Influence on Skeletal Muscle: Mass, Regeneration, and Mitochondrial Function by Pellegrino, Andrea, Tiidus, Peter M., Vandenboom, Rene

“…Human menopause is widely associated with impaired skeletal muscle quality and significant metabolic dysfunction. These observations pose significant…”
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Potentiation of force by extracellular potassium is not dependent on muscle length in mouse EDL muscle by Angelidis, Angelos, Overgaard, Kristian, Vandenboom, Rene

“…Increases in myofiber extracellular potassium with prolonged contractile activity can potentiate twitch force. Activity-dependent potentiation, another…”
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K+-induced Potentiation And Post-tetanic Potentiation Act Via Independent Mechanisms In Mouse Fast-twitch Muscle: 1616 by Overgaard, Kristian, Gittings, William, Vandenboom, Rene

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K+-induced Potentiation And Post-tetanic Potentiation Act Via Independent Mechanisms In Mouse Fast-twitch Muscle: 1616 by Overgaard, Kristian, Gittings, William, Vandenboom, Rene

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Voluntary wheel running and lithium supplementation improves muscle force production without altering SERCA function in the D2 mdx mouse by Geromella, Mia, Marcella, Bianca, Hockey, Briana, Vandenboom, Rene, Fajardo, Val

“…Abstract only Background: Duchenne muscular dystrophy (DMD) is an X-linked recessive muscle wasting disease that, with no cure, leads to early mortality (30-40…”
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Post-activation potentiation and potentiated motor unit firing patterns in boys and men by McKiel, Andrew, Woods, Stacey, Gabriel, David A, Vandenboom, Rene, Falk, Bareket

“…Background Post-activation potentiation (PAP) describes the enhancement of twitch torque following a conditioning contraction (CC) in skeletal muscle. In…”
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