Search Results - "Vandenberghe, Wim"

Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila by Cornelissen, Tom, Vilain, Sven, Vints, Katlijn, Gounko, Natalia, Verstreken, Patrik, Vandenberghe, Wim

“…Mutations in the genes for PINK1 and parkin cause Parkinson's disease. PINK1 and parkin cooperate in the selective autophagic degradation of damaged…”
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LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10 by Wauters, Fieke, Cornelissen, Tom, Imberechts, Dorien, Martin, Shaun, Koentjoro, Brianada, Sue, Carolyn, Vangheluwe, Peter, Vandenberghe, Wim

“…Parkinson disease (PD) is a disabling, incurable disorder with increasing prevalence in the western world. In rare cases PD is caused by mutations in the genes…”
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Contrast-associated acute kidney injury: does it really exist, and if so, what to do about it? [version 1; peer review: 2 approved] by Vandenberghe, Wim, Hoste, Eric

“…For decades, when contrast agents are administrated, physicians have been concerned because of the risk of inducing acute kidney injury (AKI). Recent…”
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Freezing of gait in Parkinson's disease: The impact of dual-tasking and turning by Spildooren, Joke, Vercruysse, Sarah, Desloovere, Kaat, Vandenberghe, Wim, Kerckhofs, Eric, Nieuwboer, Alice

“…Background: Turning is the most important trigger for freezing of gait (FOG) in Parkinson's disease (PD), and dual‐tasking has been suggested to influence FOG…”
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Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes by CARVAJAL-GONZALEZ, Alexander, LEITE, M. Isabel, PRESS, Raomand, LUNN, Michael P, MING LIM, MADDISON, Paul, MEINCK, H.-M, VANDENBERGHE, Wim, VINCENT, Angela, WATERS, Patrick, WOODHALL, Mark, COUTINHO, Ester, BALINT, Bettina, BETHAN LANG, PETTINGILL, Philippa, CARR, Aisling, SHEERIN, Una-Marie

“…The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and…”
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Training dual tasks together or apart in Parkinson's disease: Results from the DUALITY trial by Strouwen, Carolien, Molenaar, Esther A. L. M., Münks, Liesbeth, Keus, Samyra H. J., Zijlmans, Jan C. M., Vandenberghe, Wim, Bloem, Bastiaan R., Nieuwboer, Alice

“…ABSTRACT Background and Objectives: Many controversies surround the usefulness of dual‐task training in Parkinson's disease (PD). This study (1) compared the…”
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Beta burst coupling across the motor circuit in Parkinson's disease by Tinkhauser, Gerd, Torrecillos, Flavie, Duclos, Yann, Tan, Huiling, Pogosyan, Alek, Fischer, Petra, Carron, Romain, Welter, Marie-Laure, Karachi, Carine, Vandenberghe, Wim, Nuttin, Bart, Witjas, Tatiana, Régis, Jean, Azulay, Jean-Philippe, Eusebio, Alexandre, Brown, Peter

“…Exaggerated activity in the beta band (13–35 Hz) is a hallmark of basal ganglia signals in patients with Parkinson's disease (PD). Beta activity however is not…”
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CHCHD2 harboring Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2 by Cornelissen, Tom, Spinazzi, Marco, Martin, Shaun, Imberechts, Dorien, Vangheluwe, Peter, Bird, Matthew, De Strooper, Bart, Vandenberghe, Wim

“…The T61I mutation in coiled-coil-helix-coiled-coil-helix domain containing 2 (CHCHD2), a protein residing in the mitochondrial intermembrane space (IMS),…”
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Acute kidney injury in critical COVID-19: a multicenter cohort analysis in seven large hospitals in Belgium by Schaubroeck, Hannah, Vandenberghe, Wim, Boer, Willem, Boonen, Eva, Dewulf, Bram, Bourgeois, Camille, Dubois, Jasperina, Dumoulin, Alexander, Fivez, Tom, Gunst, Jan, Hermans, Greet, Lormans, Piet, Meersseman, Philippe, Mesotten, Dieter, Stessel, Björn, Vanhoof, Marc, De Vlieger, Greet, Hoste, Eric

“…Acute kidney injury (AKI) has been reported as a frequent complication of critical COVID-19. We aimed to evaluate the occurrence of AKI and use of kidney…”
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Testing of symmetric biphasic stimulation in Vim-DBS ET patients: a randomized-controlled pilot study by Boogers, Alexandra, Peeters, Jana, Van Bogaert, Tine, De Vloo, Philippe, Vandenberghe, Wim P, Nuttin, Bart, Mc Laughlin, Myles

“…Symmetric biphasic pulses have been shown to increase the therapeutic window compared to standard cathodic pulses in ET Vim-DBS patients. Furthermore, three…”
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Mutated ATP10B increases Parkinson’s disease risk by compromising lysosomal glucosylceramide export by Martin, Shaun, Smolders, Stefanie, Van den Haute, Chris, Heeman, Bavo, van Veen, Sarah, Crosiers, David, Beletchi, Igor, Verstraeten, Aline, Gossye, Helena, Gelders, Géraldine, Pals, Philippe, Hamouda, Norin Nabil, Engelborghs, Sebastiaan, Martin, Jean-Jacques, Eggermont, Jan, De Deyn, Peter Paul, Cras, Patrick, Baekelandt, Veerle, Vangheluwe, Peter, Van Broeckhoven, Christine

“…Parkinson’s disease (PD) is a progressive neurodegenerative brain disease presenting with a variety of motor and non-motor symptoms, loss of midbrain…”
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Functional connectivity alterations in the motor and fronto-parietal network relate to behavioral heterogeneity in Parkinson’s disease by Vervoort, Griet, Alaerts, Kaat, Bengevoord, Aniek, Nackaerts, Evelien, Heremans, Elke, Vandenberghe, Wim, Nieuwboer, Alice

“…Abstract Background Insight into the neural mechanisms of postural instability and gait disorder (PIGD) and tremor dominant (TD) subtypes in Parkinson’s…”
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On the disease and location specificity of evoked resonant neural activity by Van Bogaert, Tine, Boogers, Alexandra, Peeters, Jana, Vandenberghe, Wim, De Vloo, Philippe, Nuttin, Bart, Mc Laughlin, Myles

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Live calcium and mitochondrial imaging in the enteric nervous system of Parkinson patients and controls by Desmet, An-Sofie, Cirillo, Carla, Tack, Jan, Vandenberghe, Wim, Vanden Berghe, Pieter

“…Parkinson's disease (PD) is a neurodegenerative disease with motor and non-motor symptoms, including constipation. Therefore, several studies have investigated…”
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Open fracture of deep brain stimulation leads with normal electrical impedances by De Vloo, Philippe, Vermeulen, Lynn, Vandenberghe, Wim, Nuttin, Bart

“…•Normal-range electrical impedances can be measured from fractured DBS electrodes.•Only combining impedance measurements and imaging can rule out electrode…”
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Synaptic density in healthy human aging is not influenced by age or sex: a 11C-UCB-J PET study by Michiels, Laura, Delva, Aline, van Aalst, June, Ceccarini, Jenny, Vandenberghe, Wim, Vandenbulcke, Mathieu, Koole, Michel, Lemmens, Robin, Laere, Koen Van

“…•Cortical synaptic density is not influenced by aging over the adult life span up to 85 years.•The caudate nucleus may have a small age-dependent decrease of…”
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Structural Brain Alterations in Motor Subtypes of Parkinson's Disease: Evidence from Probabilistic Tractography and Shape Analysis by Vervoort, Griet, Leunissen, Inge, Firbank, Michael, Heremans, Elke, Nackaerts, Evelien, Vandenberghe, Wim, Nieuwboer, Alice

“…The postural instability and gait disorder (PIGD) and tremor dominant (TD) subtypes of Parkinson's disease (PD) show different patterns of alterations in…”
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Deep brain stimulation with short versus conventional pulse width in Parkinson's disease and essential tremor: A systematic review and meta-analysis by Smeets, Sara, Boogers, Alexandra, Van Bogaert, Tine, Peeters, Jana, McLaughlin, Myles, Nuttin, Bart, Theys, Tom, Vandenberghe, Wim, De Vloo, Philippe

“…To maximize clinical benefit and minimize stimulation-induced side effects, optimising deep brain stimulation (DBS) parameters is paramount. Recent literature…”
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The AKI care bundle: all bundle components are created equal—are they? by von Groote, Thilo C., Ostermann, Marlies, Forni, Lui G., Meersch-Dini, Melanie, Zarbock, Alexander

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Anodic and symmetric biphasic pulses enlarge the therapeutic window in deep brain stimulation for essential tremor by Boogers, Alexandra, Peeters, Jana, Van Bogaert, Tine, Asamoah, Boateng, De Vloo, Philippe, Vandenberghe, Wim, Nuttin, Bart, Mc Laughlin, Myles

“…Since the inception of DBS, cathodic pulses have been used. To investigate the effect of anodic and symmetric biphasic pulses on the therapeutic window (TW) in…”
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