Search Results - "Vandenberghe, Michel E."

Relevance of deep learning to facilitate the diagnosis of HER2 status in breast cancer by Vandenberghe, Michel E., Scott, Marietta L. J., Scorer, Paul W., Söderberg, Magnus, Balcerzak, Denis, Barker, Craig

“…Tissue biomarker scoring by pathologists is central to defining the appropriate therapy for patients with cancer. Yet, inter-pathologist variability in the…”
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High-throughput 3D whole-brain quantitative histopathology in rodents by Vandenberghe, Michel E., Hérard, Anne-Sophie, Souedet, Nicolas, Sadouni, Elmahdi, Santin, Mathieu D., Briet, Dominique, Carré, Denis, Schulz, Jocelyne, Hantraye, Philippe, Chabrier, Pierre-Etienne, Rooney, Thomas, Debeir, Thomas, Blanchard, Véronique, Pradier, Laurent, Dhenain, Marc, Delzescaux, Thierry

“…Histology is the gold standard to unveil microscopic brain structures and pathological alterations in humans and animal models of disease. However, due to…”
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Voxel-Based Statistical Analysis of 3D Immunostained Tissue Imaging by Vandenberghe, Michel E, Souedet, Nicolas, Hérard, Anne-Sophie, Ayral, Anne-Marie, Letronne, Florent, Balbastre, Yaël, Sadouni, Elmahdi, Hantraye, Philippe, Dhenain, Marc, Frouin, Frédérique, Lambert, Jean-Charles, Delzescaux, Thierry

“…Recently developed techniques to visualize immunostained tissues in 3D and in large samples have expanded the scope of microscopic investigations at the level…”
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In Vivo Detection of Amyloid Plaques by Gadolinium-Stained MRI Can Be Used to Demonstrate the Efficacy of an Anti-amyloid Immunotherapy by Santin, Mathieu D, Vandenberghe, Michel E, Herard, Anne-Sophie, Pradier, Laurent, Cohen, Caroline, Debeir, Thomas, Delzescaux, Thierry, Rooney, Thomas, Dhenain, Marc

“…Extracellular deposition of β amyloid plaques is an early event associated to Alzheimer's disease. Here, we have used in vivo gadolinium-stained high…”
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A validation dataset for Macaque brain MRI segmentation by Balbastre, Yaël, Rivière, Denis, Souedet, Nicolas, Fischer, Clara, Hérard, Anne-Sophie, Williams, Susannah, Vandenberghe, Michel E., Flament, Julien, Aron-Badin, Romina, Hantraye, Philippe, Mangin, Jean-François, Delzescaux, Thierry

“…Validation data for segmentation algorithms dedicated to preclinical images is fiercely lacking, especially when compared to the large number of databases of…”
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Impact of Decalcification, Cold Ischemia, and Deglycosylation on Performance of Programmed Cell Death Ligand-1 Antibodies With Different Binding Epitopes: Comparison of 7 Clones by Lawson, Nicola L., Scorer, Paul W., Williams, Gareth H., Vandenberghe, Michel E., Ratcliffe, Marianne J., Barker, Craig

“…Programmed cell death ligand-1 (PD-L1) expression levels in patients’ tumors have demonstrated clinical utility across many cancer types and are used to…”
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Primatologist: A modular segmentation pipeline for macaque brain morphometry by Balbastre, Yaël, Rivière, Denis, Souedet, Nicolas, Fischer, Clara, Hérard, Anne-Sophie, Williams, Susannah, Vandenberghe, Michel E., Flament, Julien, Aron-Badin, Romina, Hantraye, Philippe, Mangin, Jean-François, Delzescaux, Thierry

“…Because they bridge the genetic gap between rodents and humans, non-human primates (NHPs) play a major role in therapy development and evaluation for…”
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ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease by Letronne, Florent, Laumet, Geoffroy, Ayral, Anne-Marie, Chapuis, Julien, Demiautte, Florie, Laga, Mathias, Vandenberghe, Michel E., Malmanche, Nicolas, Leroux, Florence, Eysert, Fanny, Sottejeau, Yoann, Chami, Linda, Flaig, Amandine, Bauer, Charlotte, Dourlen, Pierre, Lesaffre, Marie, Delay, Charlotte, Huot, Ludovic, Dumont, Julie, Werkmeister, Elisabeth, Lafont, Franck, Mendes, Tiago, Hansmannel, Franck, Dermaut, Bart, Deprez, Benoit, Hérard, Anne-Sophie, Dhenain, Marc, Souedet, Nicolas, Pasquier, Florence, Tulasne, David, Berr, Claudine, Hauw, Jean-Jacques, Lemoine, Yves, Amouyel, Philippe, Mann, David, Déprez, Rebecca, Checler, Frédéric, Hot, David, Delzescaux, Thierry, Gevaert, Kris, Lambert, Jean-Charles

“…Although several ADAMs (A disintegrin-like and metalloproteases) have been shown to contribute to the amyloid precursor protein (APP) metabolism, the full…”
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Robust supervised segmentation of neuropathology whole-slide microscopy images by Vandenberghe, Michel E., Balbastre, Yael, Souedet, Nicolas, Herard, Anne-Sophie, Dhenain, Marc, Frouin, Frederique, Delzescaux, Thierry

“…Alzheimer's disease is characterized by brain pathological aggregates such as Aβ plaques and neurofibrillary tangles which trigger neuroinflammation and…”
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Automated cell individualization and counting in cerebral microscopic images by Zhenzhen You, Vandenberghe, Michel E., Balbastre, Yael, Souedet, Nicolas, Hantraye, Philippe, Jan, Caroline, Herard, Anne-Sophie, Delzescaux, Thierry

“…In biomedical research, cell counting is important to assess physiological and pathophysiological information. However, the automated analysis of microscopic…”
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