Search Results - "VandenBurg, M"

A 24-Week Dose-Titration Study of the Angiotensin-Converting Enzyme Inhibitor Imidapril in the Treatment of Mild-to-Moderate Essential Hypertension in the Elderly by Dews, I, VandenBurg, M

“…This multicentre, randomized, double-blind study compared the anti-hypertensive efficacy and safety of oral once-daily imidapril 5–20 mg and…”
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A comparative study of a new wireless continuous cardiorespiratory monitor for the diagnosis and management of patients with congestive heart failure at home by Andrews, D, Gouda, M S, Higgins, S, Johnson, P, Williams, A, Vandenburg, M

“…Congestive heart failure (CHF) is a major and increasing chronic disease in Western society, with a high mortality, morbidity and cost for unplanned hospital…”
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Dose finding studies with imidapril—a new ACE inhibitor by Vandenburg, MJ, Mackay, EM, Dews, I, Pullan, T, Brugier, S

“…1. We describe an approach involving a smaller, shorter study, leading onto a longer, larger study in which the antihypertensive effects of ascending doses of…”
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Sustained-release verapamil and nifedipine in exercise-induced angina pectoris by Foale, R A, Vandenburg, M J

“…In a randomised, double-blind, crossover study of oral sustained-release verapamil 360 mg o.d. ('SR-verapamil') and oral nifedipine 20 mg t.d.s. in 19 patients…”
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A large scale comparative study in general practice with nitroglycerin spray and tablet formulations in elderly patients with angina pectoris by WIGHT, L. J, VANDENBURG, M. J, POTTER, C. E, FREETH, C. J

“…In an 8-week comparative study, 410 patients were treated with nitroglycerin spray and 387 with conventional 500 mcg sublingual tablets. Data were analysed to…”
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Good clinical practice: rules, regulations and their impact on the investigator by Allen, ME, Vandenburg, MJ

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Digoxin pharmacokinetics and perindopril in heart failure patients by Vandenburg, M J, Stephens, J D, Resplandy, G, Dews, I M, Robinson, J, Desche, P

“…The influence of chronic perindopril treatment on digoxin pharmacokinetics was investigated in 10 patients with mild chronic heart failure under stable…”
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The pharmacokinetics of perindopril and its effects on serum angiotensin converting enzyme activity in hypertensive patients with chronic renal failure by Sennesael, J, Ali, A, Sweny, P, Vandenburg, M, Slovic, D, Dratwa, M, Resplandy, G, Genissel, P, Desche, P

“…1. Perindopril, an orally active angiotensin converting enzyme inhibitor, was given to 23 hypertensive patients with stable chronic renal failure for 15 days…”
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Postmarketing surveillance Is not used to promote products by Vandenburg, M

“…EDITOR, - Simon Voss and Fiona Harris's concerns about postmarketing surveillance need to be challenged. 1 Without producing any evidence the authors imply…”
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Pharmacokinetics of enalapril in normal subjects and patients with renal impairment by Kelly, JG, Doyle, G, Donohue, J, Laher, M, Vandenburg, MJ, Currie, WJ, Cooper, WD

“…The pharmacokinetics of enalaprilat were studied after administration of single and multiple doses of enalapril maleate to people with normal and impaired…”
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Effects of dilevalol (R,R‐labetalol) compared with nifedipine on heart rate, blood pressure and muscle blood flow at rest and on exercise in hypertensive patients by Walley, T, Tsao, Y, Scott, A, Mackay, E, Vandenburg, M, Breckenridge, A

“…1. Dilevalol (R,R‐labetalol) is a non‐selective beta‐adrenoceptor antagonist with beta 2‐adrenoceptor agonist activity. Its effects after 1 month's…”
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Cardiac arrhythmias following acute myocardial infarction: associations with the serum potassium level and prior diuretic therapy by Cooper, W D, Kuan, P, Reuben, S R, VandenBurg, M J

“…The relationship between the initial serum potassium level and the incidence of cardiac arrhythmias following myocardial infarction has been reviewed in a…”
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Enalapril in moderate to severe hypertension: a comparison with atenolol by Webster, J, Petrie, JC, Robb, OJ, Trafford, J, Burgess, J, Richardson, PJ, Davidson, C, Fairhurst, G, Vandenburg, MJ, Cooper, WD, et al

“…Patients with moderate to severe essential hypertension (mean untreated supine blood pressure 190/112 mm Hg) received once daily enalapril 20‐ 40 mg or…”
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A study of the potential pharmacokinetic interaction of lisinopril and digoxin in normal volunteers by Vandenburg, M J, Morris, F, Marks, C, Kelly, J G, Dews, I M, Stephens, J D

“…1. The pharmacokinetics of single oral doses of 20 mg lisinopril and 0.25 mg digoxin, given alone and together, have been studied in 12 normal young male…”
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A randomized crossover study of the blood pressure effects of tobacco and non-tobacco cigarettes by Dews, I M, VandenBurg, M J, Pullan, T R

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Financial ties as part of informed consent to postmarketing research. Attitudes of American doctors and patients by La Puma, J, Stocking, C B, Rhoades, W D, Darling, C M, Ferner, R E, Neuberger, J, VandenBurg, M, Dews, I, Tobias, J S

“…Postmarketing research, often called phase IV trials, is intended to familiarise doctors and patients with newly approved drugs. La Puma and colleagues, in…”
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Good clinical practice—a question of balance [letter; comment] by Vandenburg, MJ, Allen, ME

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Preventing fraud by Dews, I M, Vandenburg, M J

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Norfloxacin, amoxycillin, cotrimoxazole and nalidixic acid. A summary of 3-day and 7-day therapy studies in the treatment of urinary tract infections by Vogel, R, Deaney, N B, Round, E M, VandenBurg, M J, Currie, W J

“…The results of clinical trials in which norfloxacin was used for 7 days compared with amoxycillin or cotrimoxazole, or for 3 days compared with citrated…”
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Good clinical practice: a way to better drugs by Vandenburg, M J, Gerlis, L, Nutley, P

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